Abstract: The invention refers to a method for culturing cells in a substrate in which a chamber having at least one side wall, a bottom, and a top is formed, comprising introduction of cells into the chamber, tilting of the substrate such that the cells accumulate on a side wall of the chamber, and holding the substrate in the tilted orientation such that the cells form a three-dimensional cell aggregate.

Abstract: The invention refers to a method for culturing cells. The cells are cultured in a substrate, wherein in the substrate a fluid channel system is formed, comprising a culturing channel having a culturing access to the outside, a storage channel having a storage access to the outside, and a transfer channel having a transfer access to the outside, wherein the culturing channel and the storage channel are fluidically connected to each other via the transfer channel.

Abstract: The present invention relates to a cover device for a sample carrier, comprising a sticky surface area for connection to the sample carrier, wherein the sticky surface area is configured such that the sample carrier is covered in liquid-tight fashion after connection of the cover device to the sample carrier in the sticky surface area.

Abstract: The application relates to an apparatus for providing a gas for the introduction thereof into an incubation chamber, comprising an inlet port (1) for introducing a gas, an outlet port (2) for discharging a gas, a first gas path (3) connecting the inlet port (1) to the outlet port (2), a second gas path (4) branching off from the first gas path (3) and running back into the first gas path (3); a distributing element (5), configured to allow a portion of the gas introduced through the inlet port (1) to be conducted via the second gas path (4), and an enriching element (6) arranged in the second gas path for enriching the gas flow with a liquid.

Abstract: The invention relates to a sample chamber for testing samples, comprising a bottom plate and a cover plate connected thereto, a sample reservoir for receiving a liquid and/or a sample to be tested, and a contact electrode which is arranged entirely in the bottom plate, in the cover plate or between the bottom plate and the cover plate and which is electrically conductively connected to a conductor element or semiconductor element disposed in and/or on the sample chamber, wherein the bottom plate and/or the cover plate are designed in such a way that an electrical contact with the contact electrode can be established from the outside in such a way that an electrically conductive connection to the conductor element or to the semiconductor element can be established from the outside through the bottom plate or through the cover plate via the contact electrode.

Abstract: The invention relates to a method of positioning an organic, biological and/or medical specimen in a desired partial region of a specimen carrier, comprising the steps arrangement of a gel in a partial region of the specimen carrier, polymerization or gelification of the gel, by means of which a polymerized gel is obtained, whereby the polymerized gel at least partially, in particular horizontally, delimits the desired partial region and introduction of the specimen into the specimen carrier, in particular into the desired partial region of the specimen carrier.

Abstract: A microfluid device for producing diffusively built gradients comprising a bottom plate and a cover plate, wherein the cover plate has recesses and is connected to the bottom plate in a liquid-tight manner so that the recesses form at least two reservoirs and one observation chamber, which connects the reservoir, a reservoir can be filled particularly through an inlet/outlet through the cover plate, and the cross-sectional surface of the observation chamber is at least 5 times, preferably at least 200 times smaller at the aperture of the observation chamber into one of the reservoirs than the maximum cross-sectional surface of the reservoir in parallel to this cross-sectional surface of the observation chamber.

Abstract: The invention relates to polymer substrates which are provided with fluorescence features and in which photochemical fluorescence features, i.e. fluorescent structures, are produced by UV irradiation. Thus, fluorophores can be produced in polymer substrates with a low inherent fluorescence by means of suitable UV radiation, which fluorophores display a marked and detectable emission upon being excited with light of a suitable wavelength. If such an irradiation is implemented in a structured manner, emission patterns can be produced in this way in polymer substrates, which emission patterns can be applied for example as recovery grids in fluorescence microscopy. A further application field relates to product authentication which is made possible by the polymer substrates according to the invention provided with fluorescence features.

Abstract: The invention comprises a sample chamber for microscopic examinations, comprising a reservoir for receiving a sample, the reservoir being defined by a bottom plate and a side wall, and a parting plate disposed in the reservoir and being parallel to the bottom plate, the parting plate in the reservoir being disposed at a height which is lower than the minimum height of the side wall, so that it divides the reservoir into an upper and a lower partial reservoirs, the lower partial reservoir and the upper partial reservoir being laterally completely bordered by the side wall, and the upper and the lower partial reservoirs being connected by at least one inlet/outlet.

Abstract: The invention comprises a method of manufacturing a sample chamber, comprising the steps of: providing a first (20) and a second (30) component, the first component (20) comprising an elastomer; treating the elastomer in the region of a contact surface of the first component (20) and/or treating a contact surface of the second component (30) with a plasma, with plasma waste gas, and/or with a reactive gas; and connecting the contact surface of the first component (20) with the contact surface of the second component (30).

Abstract: The application relates to an apparatus for providing a gas for the introduction thereof into an incubation chamber, comprising an inlet port (1) for introducing a gas, an outlet port (2) for discharging a gas, a first gas path (3) connecting the inlet port (1) to the outlet port (2), a second gas path (4) branching off from the first gas path (3) and running back into the first gas path (3); a distributing element (5), configured to allow a portion of the gas introduced through the inlet port (1) to be conducted via the second gas path (4), and an enriching element (6) arranged in the second gas path for enriching the gas flow with a liquid.

Abstract: A microfluid device for producing diffusively built gradients comprising a bottom plate and a cover plate, wherein the cover plate has recesses and is connected to the bottom plate in a liquid-tight manner so that the recesses form at least two reservoirs and one observation chamber, which connects the reservoir, a reservoir can be filled particularly through an inlet/outlet through the cover plate, and the cross-sectional surface of the observation chamber is at least 5 times, preferably at least 200 times smaller at the aperture of the observation chamber into one of the reservoirs than the maximum cross-sectional surface of the reservoir in parallel to this cross-sectional surface of the observation chamber.

Abstract: A microfluid device for producing diffusively built gradients comprising a bottom plate and a cover plate, wherein the cover plate has recesses and is connected to the bottom plate in a liquid-tight manner so that the recesses form at least two reservoirs and one observation chamber, which connects the reservoir, a reservoir can be filled particularly through an inlet/outlet through the cover plate, and the cross-sectional surface of the observation chamber is at least 5 times, preferably at least 200 times smaller at the aperture of the observation chamber into one of the reservoirs than the maximum cross-sectional surface of the reservoir in parallel to this cross-sectional surface of the observation chamber.

Abstract: A method of positioning an organic, biological and/or medical specimen in a desired surface region of a specimen carrier, whereby a magnet device is provided, including joining the specimen with one or a plurality of magnetic, in particular paramagnetic particles, arrangement of the magnet device relative to the specimen carrier so that a desired magnetic field arrangement is provided in a predetermined region of the specimen carrier, introduction of the specimen into the specimen carrier and arrangement of the specimen in the desired surface region with the aid of the magnet device.

Abstract: The invention comprises a sample chamber for microscopic examinations, comprising a reservoir for receiving a sample, the reservoir being defined by a bottom plate and a side wall, and a parting plate disposed in the reservoir and being parallel to the bottom plate, the parting plate in the reservoir being disposed at a height which is lower than the minimum height of the side wall, so that it divides the reservoir into an upper and a lower partial reservoirs, the lower partial reservoir and the upper partial reservoir being laterally completely bordered by the side wall, and the upper and the lower partial reservoirs being connected by at least one inlet/outlet.

Abstract: The invention relates to a sample chamber with a cover plate and a bottom plate which is joined thereto in a fixed manner, wherein a recess is provided in the cover plate so that a reservoir is formed by the bottom plate, wherein a planar element with holes is provided in the reservoir, wherein the holes have a predetermined arrangement and/or size.

Abstract: The invention relates to a specimen carrier for the study of cell growth, comprising a substrate with a reservoir with a bottom, wherein the reservoir is filled up to a predetermined height of the side wall, which is smaller than the complete height of the reservoir, with a carrier material for cell growth and the side wall of the reservoir is formed such that a predetermined contact angle of the carrier material can be adjusted with respect to the side wall.

Abstract: A microfluid system includes at least one flow-through volume, and at least one connector connected to the flow-through volume. The microfluid system includes a structured surface having at least one elevation. Each elevation is a tapered elevation. Each connector is formed in a respective elevation and is configured as a tapered recess.

Abstract: A sample chamber of plastics has at least one receiving area for receiving a liquid, and includes an oleophobic layer in a predetermined surface area. The sample chamber includes a base plate and a cover plate firmly connected thereto. The oleophobic layer is disposed on a side of the base plate and the cover plate facing away from the receiving areas, and/or the sample chamber consists of a plastic body and the oleophobic layer is disposed on a side of the plastic body facing away from the receiving areas.

Abstract: The present invention relates to a valve unit for a microfluid system comprising a first and a second fluid reservoir, a flow chamber, a fluid channel array and a conveying means, said first fluid reservoir being, via the flow chamber, in fluidic communication with the second fluid reservoir through the fluid channel array, wherein the valve unit can be brought from a first state to a second state so that, in said first state, a fluid can be conveyed by the conveying means from said first fluid reservoir through the flow chamber in a predetermined direction of flow into the second fluid reservoir, and so that, in said second state, a fluid can be conveyed by the conveying means from said second fluid reservoir through the flow chamber in a predetermined direction of flow into the first fluid reservoir.