Abstract: An external patch containing diclofenac hydroxyethylpyrrolidine prepared by laminating an adhesive layer on a backing, wherein said adhesive layer is characterized by comprising 5-50% by weight of styrene•isoprene•styrene block copolymer, 20-50% by weight of a tackifier resin, 5-70% by weight of a softening agent, and 0.5-20% by weight of one or more solubilizers selected from N-methyl-2-pyrrolidone, propylene glycol and dimethyl sulfoxide as essential ingredients, and 0.5-20% by weight of diclofenac hydroxyethylpyrrolidine as an active ingredient. The patch has excellent transdermal absorption, less skin-irritation and excellent stability of the drug.

Abstract: An improved dropper bottle, and in particular a dropper body able to be joined to a container body and closed by a cap, are described. The dropper body comprises a first droplet delivery end and an open base, the open base of the dropper body comprising a first projection able to engage with the internal surface of a mouth of the container body, and a second projection able to engage with the external surface of the mouth of the container body. Locking toothing is provided between the dropper body and the container body.

Abstract: An improved dropper bottle, and in particular a dropper body able to be joined to a container body and closed by a cap, are described. The dropper body comprises a first droplet delivery end and an open base, the open base of the dropper body comprising a first projection able to engage with the internal surface of a mouth of the container body, and a second projection able to engage with the external surface of the mouth of the container body. Locking toothing is provided between the dropper body and the container body.