Patents Assigned to ICELL GENE THERAPEUTICS LLC
  • Chimeric antigen receptor (CAR) targeting multiple antigens, compositions and methods of use thereof
    Patent number: 11173179
    Abstract: The present disclosure relates to compositions and methods relating to chimeric antigen receptor (CAR) polypeptides and methods relating thereto. In one embodiment, the present disclosure relates to engineered cells having chimeric antigen receptor polypeptides directed to at least two targets. In another embodiment, the present disclosure relates to engineered cells having chimeric antigen receptor polypeptides and an enhancer moiety.
    Type: Grant
    Filed: February 10, 2018
    Date of Patent: November 16, 2021
    Assignee: ICELL GENE THERAPEUTICS LLC
    Inventors: Yupo Ma, Kevin Pinz, Xun Jiang, Masayuki Wada, Kevin Chen
  • Chimeric antigen receptors (CARs), targeting hematologic malignancies, compositions and methods of use thereof
    Patent number: 10273280
    Abstract: The present disclosure provides chimeric antigen receptor polypeptides having antigen recognition domains for CD2, CD3, CD4, CD5, CD7, CD8, and CD52 antigens, and polynucleotides encoding for the same. The present disclosure also provides for engineered cells expressing the polynucleotide or polypeptides. In some embodiments, the disclosure provides methods for treating diseases associated with CD2, CD3, CD4, CD5, CD7, CD8, and CD52 antigens.
    Type: Grant
    Filed: February 26, 2016
    Date of Patent: April 30, 2019
    Assignee: ICELL GENE THERAPEUTICS LLC
    Inventors: Yupo Ma, Kevin Pinz, Xun Jiang, Masayuki Wada, Kevin Chen