Patents Assigned to ICONIC THERAPEUTICS, INC.
  • Anti-tissue factor antibodies, antibody-drug conjugates, and related methods
    Patent number: 11447566
    Abstract: Provided herein are antibodies that specifically bind to human tissue factor (TF), anti-TF antibody-drug conjugates (ADCs), and compositions comprising the antibodies or ADCs. Also provided herein are methods of making and using the antibodies or ADCs, such as therapeutic and diagnostic methods.
    Type: Grant
    Filed: August 26, 2021
    Date of Patent: September 20, 2022
    Assignee: Iconic Therapeutics, Inc.
    Inventors: Jan-Willem Theunissen, Andrew D. Avery, II, Allen G. Cai, Anthony Byron Cooper, Thi-Sau Migone
  • Homogeneous Preparations of Chimeric Protein
    Publication number: 20080193441
    Abstract: Variant forms of chimeric protein molecules comprising a Factor VII moiety and an Fe region of an IgG1 moiety provide improved properties. The variants are more resistant to proteolytic degradation. Thus preparations of the variant forms are more homogeneous and have a longer half-life. The variant forms are used for treating cancer, atherosclerosis, psoriasis, diabetic retinopathy, wet macular degeneration, and rheumatoid arthritis.
    Type: Application
    Filed: November 10, 2004
    Publication date: August 14, 2008
    Applicant: ICONIC THERAPEUTICS, INC.
    Inventors: Patrick W. Trown, Michael I. Sherman, Kirk Dornbush