Abstract: The present invention relates to a process for preparing methoxy polyethylene glycol ethylmaleimide (abbreviated to as “mPEG-ethylmaleimide”) and derivatives thereof with high purity. methoxypolyethyleneglycol ethylmaleimide therefrom.
Type:
Application
Filed:
March 18, 2008
Publication date:
December 9, 2010
Applicant:
ID BIOCHEM, INC.
Inventors:
Pyeong-Uk Park, Seong-Nyun Kim, Su-Chan Kim, Jung-Oh Kwon
Abstract: The present invention relates to a preparing method of methoxypolyethyleneglycol (mPEG) with high purity and derivatives thereof. More precisely, the method of the present invention to prepare high purity mPEG with at least 99% of purity, up to 1.05 of molecular weight distribution and 350˜100,000 of molecular weight includes the process of reacting commercial mPEG having low purity to give highly purified intermediates, mPEG-acetic acid of formula 1 and mPEG-phthalate of formula 2.
Type:
Grant
Filed:
August 3, 2006
Date of Patent:
August 24, 2010
Assignee:
ID Biochem, Inc.
Inventors:
Pyeong-Uk Park, Seong-Neon Kim, Chong-Gu Lee, Ju-Sung Lee
Abstract: The present invention relates to a preparing method of methoxypolyethyleneglycol (mPEG) with high purity and derivatives thereof. More precisely, the method of the present invention to prepare high purity mPEG with at least 99% of purity, up to 1.05 of molecular weight distribution and 350˜100,000 of molecular weight includes the process of reacting commercial mPEG having low purity to give highly purified intermediates, mPEG-acetic acid of formula 1 and mPEG-phthalate of formula 2.
Type:
Application
Filed:
August 3, 2006
Publication date:
April 17, 2008
Applicant:
ID BIOCHEM INC.
Inventors:
Pyeong-Uk Park, Seong-Neon Kim, Chong-Gu Lee, Ju-Sung Lee