Patents Assigned to IDEA SEED, LLC
  • BRCA2-mediated purification of recombinase protein
    Patent number: 11208444
    Abstract: The invention is the products and methods associated with purifying overexpressed recombinant recombinases from a host cell line resulting in an un-tagged protein of interest without any additional, non-native amino acids. The invention employs at least one DNA vector that co-expresses a tagged fusion protein and the recombinase protein with the recombinase protein having an affinity for binding to the tagged fusion protein. Isolation methods of the recombinase protein include the targeting of the tagged fusion protein.
    Type: Grant
    Filed: February 28, 2020
    Date of Patent: December 28, 2021
    Assignee: Idea Seed, LLC.
    Inventor: Michael Longo
  • Recombinase Purification
    Publication number: 20200291080
    Abstract: The invention is the products and methods associated with purifying overexpressed recombinant recombinases from a host cell line resulting in an un-tagged protein of interest without any additional, non-native amino acids. The invention employs at least one DNA vector that co-expresses a tagged fusion protein and the recomibinase protein with the recombinase protein having an affinity for binding to the the tagged fusion protein. Isolation methods of the recominbase protein include the targeting of the tagged fusion protein.
    Type: Application
    Filed: February 28, 2020
    Publication date: September 17, 2020
    Applicant: Idea Seed, LLC
    Inventor: Michael Longo
  • BRCA2 mediated protein purification recombinase
    Patent number: 10604778
    Abstract: The invention is the products and methods associated with purifying overexpressed recombinant recombinases from a host cell line resulting in an un-tagged protein of interest without any additional, non-native amino acids. The invention employs at least one DNA vector that co-expresses a tagged fusion protein and the recombinase protein with the recombinase protein having an affinity for binding to the the tagged fusion protein. Isolation methods of the recombinase protein include the targeting of the tagged fusion protein.
    Type: Grant
    Filed: March 7, 2016
    Date of Patent: March 31, 2020
    Assignee: IDEA SEED, LLC
    Inventor: Michael Longo