Patents Assigned to IDIENCE CO., LTD.
  • METHODS OF TREATING DISORDERS WITH PHTHALAZINONE DERIVATIVES
    Publication number: 20250312342
    Abstract: The present invention relates to methods of treating disorders (e.g. breast cancer, ovarian cancer, or pancreatic cancer) with a derivatives having poly (ADP-ribose) polymerase inhibitors or pharmaceutical compositions thereof.
    Type: Application
    Filed: June 2, 2022
    Publication date: October 9, 2025
    Applicant: IDIENCE CO., LTD.
    Inventors: Won Sik LEE, Eun-Jihn ROH, Myongjae LEE, Minju HONG, Seunghee SONG
  • PHARMACEUTICAL COMPOSITION INCLUDING PHTHALAZINONE DERIVATIVE FOR CO-ADMINISTRATION WITH ANTICANCER DRUG
    Publication number: 20250120970
    Abstract: A combination of pharmaceutical compositions for co-administration is disclosed. The combination includes (i) a first pharmaceutical composition containing a phthalazinone derivative and (ii) a second pharmaceutical composition containing at least one anticancer drug. The combination exhibits an excellent synergistic effect compared to the conventional administration of an anticancer drug alone. The first and the second pharmaceutical compositions can be in a form of a mixture, or are each formulated and administered simultaneously or sequentially.
    Type: Application
    Filed: January 25, 2023
    Publication date: April 17, 2025
    Applicant: IDIENCE CO., LTD.
    Inventors: Won Sik LEE, Kyoung Soo HA, Eun-Jihn ROH, Myongjae LEE, Minju HONG, Sungyeon CHOI, Jeong Eun KIM, In-Gyu JE, Yeongran YOO, Jong-Ha LIM
  • Pharmaceutical composition comprising phthalazinone derivatives
    Patent number: 12059419
    Abstract: The present invention relates to stable pharmaceutical composition comprising phthalazinone derivatives having good activity as poly (ADP-ribose) polymerase inhibitors.
    Type: Grant
    Filed: October 16, 2020
    Date of Patent: August 13, 2024
    Assignee: IDIENCE CO., LTD.
    Inventors: Daeun Jeon, Jeongeun Lee, Jinhyuk Jeong, Kyuho Jeong
  • Process for preparing a phthalazinone derivative and intermediates thereof
    Patent number: 12060345
    Abstract: The present application provides a method of preparing 4-[3-(3-[(cyclopropylamino)methyl]azetidine-1-carbonyl)-4-fluorobenzyl]phthalazin-1(2H)-one, or a pharmaceutically acceptable salt thereof, intermediates in the preparation thereof, methods of preparing the intermediates, and compositions and products comprising 4-[3-(3-[(cyclopropylamino)methyl]azetidine-1-carbonyl)-4-fluorobenzyl]phthalazin-1(2H)-one made from the methods that result in high purity and yield.
    Type: Grant
    Filed: April 24, 2020
    Date of Patent: August 13, 2024
    Assignee: IDIENCE CO., LTD.
    Inventors: Keuncheol Ryu, Seoktaek Lee, Hanna Seo, Hyeran Yang, Wonje Seong, Jinyoung Yoon
  • Crystalline forms of phthalazinone compound
    Patent number: 11390608
    Abstract: The present specification provides crystalline forms of 4-[3-(3-[(cyclopropylamino)methyl]azetidine-1-carbonyl)-4-fluorobenzyl]phthalazin-1(2H)-one hydrochloride, methods of preparing the same, and pharmaceutical compositions comprising the same.
    Type: Grant
    Filed: April 24, 2020
    Date of Patent: July 19, 2022
    Assignee: IDIENCE CO., LTD.
    Inventors: Kunhee Lee, Seoktaek Lee, Keuncheol Ryu, Hanna Seo, Hyeran Yang, Wonje Seong, Jinyoung Yoon
  • Phthalazinone derivatives and manufacturing process thereof
    Patent number: RE49338
    Abstract: The present invention relates to phthalazinone derivatives, including pharmaceutical compositions and for the preparation of phthalazinone derivatives. And more particularly the present invention provided a pharmaceutical composition of phthalazinone derivatives for inhibiting activity of the Poly(ADP-riboside) polymerase enzyme.
    Type: Grant
    Filed: June 20, 2019
    Date of Patent: December 20, 2022
    Assignee: IDIENCE CO., LTD.
    Inventors: Jae-Hoon Kang, Hong-Sub Lee, Yoon-Suk Lee, Joon-Tae Park, Kyung-Mi An, Jin-Ah Jeong, Kyung-Sun Kim, Jeong-Geun Kim, Chang-Hee Hong, Sun-Young Park, Dong-Keun Song, Yong-Don Yun