Patents Assigned to IEP
  • Patent number: 10291017
    Abstract: There is provided an integration of the leakage current functions of an RCD and the voltage sensing functions of other prior art protection devices. By integrating the two capabilities into one decision making system/algorithm, and considering the circuits performance in terms of leakage current as it correlated with elevated protective earth voltages (and vice versa), an embodiment is created which is able to “look into” a protected electrical system and make much more precise and discerning decisions on electrical status and probability of unsafe events. The resultant technology attends to the outstanding issues with the prior art technologies as they stand, and provides a protection solution that covers the entire range of electrical power wiring configurations and the practical complexities of modern electrical works.
    Type: Grant
    Filed: June 10, 2014
    Date of Patent: May 14, 2019
    Assignee: IEP2 RESEARCH PTY LIMITED
    Inventors: Richard Harris, Geoffrey Rubython
  • Publication number: 20160134105
    Abstract: There is provided an integration of the leakage current functions of an RCD and the voltage sensing functions of other prior art protection devices. By integrating the two capabilities into one decision making system/algorithm, and considering the circuits performance in terms of leakage current as it correlated with elevated protective earth voltages (and vice versa), an embodiment is created which is able to “look into” a protected electrical system and make much more precise and discerning decisions on electrical status and probability of unsafe events. The resultant technology attends to the outstanding issues with the prior art technologies as they stand, and provides a protection solution that covers the entire range of electrical power wiring configurations and the practical complexities of modern electrical works.
    Type: Application
    Filed: June 10, 2014
    Publication date: May 12, 2016
    Applicant: IEP2 RESEARCH PTY LIMITED
    Inventors: Richard HARRIS, Geoffrey RUBYTHON
  • Patent number: 9228214
    Abstract: In a process for the enantioselective enzymatic reduction of a hydroxy ketone of general formula I wherein R1?C1-C6 alkyl and R2?—Cl, —CN, —OH, —H or C1-C6 alkyl, into a chiral diol of general formula II wherein R1 and R2 have the same meaning as in formula I, the hydroxy ketone is reduced with an oxidoreductase in the presence of NADH or NADPH as a cofactor, wherein a) the hydroxy ketone is provided in the reaction at a concentration of ?50 g/l, b) the oxidized cofactor NAD or NADP having formed is regenerated continuously by oxidation of a secondary alcohol of general formula RXRYCHOH, wherein RX, RY independently represent hydrogen, branched or unbranched C1-C8-alkyl and Ctotal?3, and c) the reduction of the hydroxy ketone and the oxidation of the secondary alcohol are catalyzed by the same oxidoreductase.
    Type: Grant
    Filed: February 4, 2015
    Date of Patent: January 5, 2016
    Assignee: CAMBREX IEP GMBH
    Inventors: Antje Gupta, Maria Dupont, Anke Tschentscher
  • Publication number: 20150152451
    Abstract: In a process for the enantioselective enzymatic reduction of a hydroxy ketone of general formula I wherein R1=C1-C6 alkyl and R2?—Cl, —CN, —OH, —H or C1-C6 alkyl, into a chiral diol of general formula II wherein R1 and R2 have the same meaning as in formula I, the hydroxy ketone is reduced with an oxidoreductase in the presence of NADH or NADPH as a cofactor, wherein a) the hydroxy ketone is provided in the reaction at a concentration of ?50 g/l, b) the oxidized cofactor NAD or NADP having formed is regenerated continuously by oxidation of a secondary alcohol of general formula RXRYCHOH, wherein RX, RY independently represent hydrogen, branched or unbranched C1-C8-alkyl and Ctotal?3, and c) the reduction of the hydroxy ketone and the oxidation of the secondary alcohol are catalyzed by the same oxidoreductase.
    Type: Application
    Filed: February 4, 2015
    Publication date: June 4, 2015
    Applicant: CAMBREX IEP GMBH
    Inventors: Antje GUPTA, Maria DUPONT, Anke TSCHENTSCHER
  • Patent number: 9045780
    Abstract: In a process for the stereoselective, in particular enantioselective enzymatic reduction of keto compounds to the corresponding chiral hydroxy compounds, wherein the keto compounds are reduced with an enantioselective, NADH-specific oxidoreductase, a polypeptide is used for reducing the keto compounds, which polypeptide exhibits an R-ADH-signature H-[P; A]-[I; A; Q; V; L]-[G; K]-R at positions 204-208 and the following further structural features in their entirety: (i) an N-terminal Rossmann-Fold GxxxGxG, (ii) an NAG-motif at position 87, (iii) a catalytic triad consisting of S 139, Y 152 and K 156, (iv) a negatively charged amino acid moiety at position 37, (v) two C-terminal motifs in the dimerization domain [A; S]-S-F and [V; I]-DG-[G; A]-Y-[T; C; L]-[A; T; S]-[Q; V; R; L; P], (vi) Val or Leu at position 159 (4 positions downstream of K 156), (vii) Asn at position 178, and (viii) a proline moiety at position 188.
    Type: Grant
    Filed: March 3, 2010
    Date of Patent: June 2, 2015
    Assignee: IEP GMBH
    Inventors: Antje Gupta, Maria Bobkova, Anke Tschentscher
  • Patent number: 9040265
    Abstract: The invention relates to a process for the enantioselective enzymatic reduction of a keto compound to the corresponding chiral hydroxy compound, wherein the keto compound is reduced with an oxidoreductase in the presence of a cofactor, and is characterized in that an oxidoreductase is used which has an amino acid sequence in which (a) at least 70% of the amino acids are identical to the amino acids of one of the amino acid sequences SEQ ID No 1, SEQ ID No 6 and SEQ ID No 8, or (b) at least 55% of the amino acids are identical to the amino acids of the amino acid sequence SEQ ID No 2, or (c) at least 65% of the amino acids are identical to the amino acids of the amino acid sequence SEQ ID No 3, or (d) at least 75% of the amino acids are identical to the amino acids of the amino acid sequence SEQ ID No 4, or (e) at least 65% of the amino acids are identical to the amino acids of the amino acid sequence SEQ ID No 5, or (0 at least 50% of the amino acids are identical to the amino acids of the amino acid sequence
    Type: Grant
    Filed: October 25, 2011
    Date of Patent: May 26, 2015
    Assignee: IEP GMBH
    Inventors: Anke Tschentscher, Antje Gupta, Maria Bobkova
  • Patent number: 8980592
    Abstract: In a process for the enantioselective enzymatic reduction of a hydroxy ketone of general formula I wherein R1=C1-C6 alkyl and R2=—Cl, —CN, —OH, —H or C1-C6 alkyl, into a chiral diol of general formula II wherein R1 and R2 have the same meaning as in formula I, the hydroxy ketone is reduced with an oxidoreductase in the presence of NADH or NADPH as a cofactor, wherein a) the hydroxy ketone is provided in the reaction at a concentration of ?50 g/l, b) the oxidized cofactor NAD or NADP having formed is regenerated continuously by oxidation of a secondary alcohol of general formula RXRYCHOH, wherein RX, RY independently represent hydrogen, branched or unbranched C1-C8-alkyl and Ctotal?3, and c) the reduction of the hydroxy ketone and the oxidation of the secondary alcohol are catalyzed by the same oxidoreductase.
    Type: Grant
    Filed: December 14, 2006
    Date of Patent: March 17, 2015
    Assignee: Cambrex IEP GmbH
    Inventors: Antje Gupta, Maria Bobkova, Anke Tschentscher
  • Patent number: 8953288
    Abstract: A protection system for an IT electrical distribution system (EDS) has a floating reference conductor and two electrical conductors in the form of an active conductor and a neutral conductor. System includes two input terminals for electrically connecting to an MEN electrical power source that is upstream of system. Two output terminals are electrically connected to an electrical load in the form of an electrical motor for a compressor of an upright freezer display. A motor protection device, in the form of an MCB, electrically connects terminals to allow a supply of electrical power to a motor. The MCB is responsive to a fault signal at a port for selectively electrically disconnecting at least one of the terminals. A sentinel unit selectively generates the fault signal at port in response to the current in conductor being greater than a predetermined threshold.
    Type: Grant
    Filed: December 21, 2009
    Date of Patent: February 10, 2015
    Assignee: IEP2 Research Pty Limited
    Inventors: David Paul Jankowski, Geoffrey Rubython, Wayne Callen, Walter Henry Berryman
  • Patent number: 8953295
    Abstract: A protection system for an IT electrical distribution system (EDS) has a floating reference conductor and two electrical conductors in the form of an active conductor and a neutral conductor. System includes two input terminals for electrically connecting to an MEN electrical power source that is upstream of system. Two output terminals are electrically connected to an electrical load in the form of an electrical motor for a compressor of an upright freezer display. Motor is downstream of the system. A protection device, in the form of an MCB, electrically connects terminals to allow a supply of electrical power from source to motor. MCB is responsive to a fault signal at a port for selectively electrically disconnecting at least one of terminals to prevent the supply of electrical power. A sentinel unit selectively generates the fault signal at port in response to the current in conductor being greater than a predetermined threshold.
    Type: Grant
    Filed: December 21, 2009
    Date of Patent: February 10, 2015
    Assignee: IEP2 Research Pty Limited
    Inventors: David Paul Jankowski, Geoffrey Rubython, Wayne Callen, Walter Henry Berryman
  • Patent number: 8932835
    Abstract: A process for the enantioselective enzymatic reduction of a keto compound of general formula I wherein R may represent any protective group for amino functions (tert. butyloxycarbonyl group (BOC), benzyloxycarbonyl group, 9-fluorenylmethoxycarbonyl group) and X?—Cl, —CN, —OH, Br, F.
    Type: Grant
    Filed: September 22, 2008
    Date of Patent: January 13, 2015
    Assignee: IEP GmbH
    Inventors: Antje Gupta, Maria Bobkova, Anke Tschentscher
  • Publication number: 20140175334
    Abstract: The invention concerns a capture mass for capturing heavy metals in a liquid or gaseous effluent, comprising a porous solid support, copper sulphide and at least one second metal sulphide the metal of which is selected from the group constituted by chromium, manganese, iron, cobalt and nickel, and in which the ratio of the percentage by weight of the metal or metals other than copper to the percentage by weight of copper is in the range 0.01 to 2. The invention also concerns a process for preparing said capture mass and a process for capturing heavy metals in a gaseous or liquid effluent, in which said effluent is brought into contact with said capture mass.
    Type: Application
    Filed: December 17, 2013
    Publication date: June 26, 2014
    Applicant: IEP Energies nouvelles
    Inventors: Fabien PORCHERON, Arnaud BAUDOT, Karin BARTHELET
  • Patent number: 8361765
    Abstract: The invention relates to an enzymatic method for the enantioselective reduction of organic keto compounds to the corresponding chiral hydroxy compounds, an alcohol dehydrogenase from Lactobacillus minor and a method for the enantioselective production of (S)-hydroxy compounds from a racemate.
    Type: Grant
    Filed: June 19, 2007
    Date of Patent: January 29, 2013
    Assignee: IEP GmbH
    Inventors: Antje Gupta, Klaus Breese, Gert Bange, Peter Neubauer
  • Patent number: 8323936
    Abstract: The invention relates to a process for the enantioselective enzymatic reduction of secodione derivatives. The secodione derivative is reduced with an oxidoreductase/dehydrogenase in the presence of NADH or NADPH as a cofactor. The secodione derivative is used in the reaction batch at a concentration of ?10 g/l and the oxidized cofactor NAD or NADP formed by the oxidoreductase/dehydrogenase is regenerated continuously.
    Type: Grant
    Filed: September 7, 2011
    Date of Patent: December 4, 2012
    Assignee: IEP GmbH
    Inventors: Antje Gupta, Anke Tschentscher, Maria Bobkova
  • Patent number: 8227208
    Abstract: A process for the enantioselective reduction of compounds having a steroid structure (ABCD) including one or several heteroatoms, one or several double bonds and/or aromatic components in the ring structure and having at least one oxo group at positions 3, 7, 11, 12 or 17 in the steroid ring system or in the a-position of any carbon moiety of the steroid structure: comprising providing the oxosteroid compound in the reaction at a concentration of ?50 g/L, a reduced cofactor NADH or NADPH, a hydroxysteroid dehydrogenase and a secondary alcohol or cycloalknaol to effect the enantioselective reduction.
    Type: Grant
    Filed: April 11, 2007
    Date of Patent: July 24, 2012
    Assignee: IEP GmbH
    Inventors: Antje Gupta, Anke Tschentscher, Maria Bobkova
  • Patent number: 8158406
    Abstract: The present invention relates to a process for the enantioselective enzymatic reduction of keto compounds, in particular of 4-halo-3-oxobutyric acid esters, to the corresponding R-alcohols or S-4-halo-3-hydroxybutyric acid esters, respectively, using an R-specific oxidoreductase in the presence of a cofactor.
    Type: Grant
    Filed: February 21, 2006
    Date of Patent: April 17, 2012
    Assignee: IEP GmbH
    Inventors: Antje Gupta, Maria Bobkova, Anke Tschentscher
  • Publication number: 20120040425
    Abstract: In a process for the stereoselective, in particular enantioselective enzymatic reduction of keto compounds to the corresponding chiral hydroxy compounds, wherein the keto compounds are reduced with an enantioselective, NADH-specific oxidoreductase, a polypeptide is used for reducing the keto compounds, which polypeptide exhibits an R-ADH-signature H-[P; A]-[I; A; Q; V; L]-[G; K]-R at positions 204-208 and the following further structural features in their entirety: (i) an N-terminal Rossmann-Fold GxxxGxG, (ii) an NAG-motif at position 87, (iii) a catalytic triad consisting of S 139, Y 152 and K 156, (iv) a negatively charged amino acid moiety at position 37, (v) two C-terminal motifs in the dimerization domain [A; S]-S-F and [V; I]-DG-[G; A]-Y-[T; C; L]-[A; T; S]-[Q; V; R; L; P], (vi) Val or Leu at position 159 (4 positions downstream of K 156), (vii) Asn at position 178, and (viii) a proline moiety at position 188.
    Type: Application
    Filed: March 3, 2010
    Publication date: February 16, 2012
    Applicant: IEP GMBH
    Inventors: Antje Gupta, Maria Bobkova, Anke Tschentscher
  • Publication number: 20120040424
    Abstract: The invention relates to a process for the enantioselective enzymatic reduction of secodione derivatives. The secodione derivative is reduced with an oxidoreductase/dehydrogenase in the presence of NADH or NADPH as a cofactor. The secodione derivative is used in the reaction batch at a concentration of ?10 g/l and the oxidized cofactor NAD or NADP formed by the oxidoreductase/dehydrogenase is regenerated continuously.
    Type: Application
    Filed: September 7, 2011
    Publication date: February 16, 2012
    Applicant: IEP GMBH
    Inventors: Antje GUPTA, Anke TSCHENTSCHER, Maria BOBKOVA
  • Patent number: 8021637
    Abstract: Described is a process for the preparation of at least one crystallized lamellar solid formed by magadiite or kenyaite consisting of implementing in a step (i) mixing of at least one silica source, at least one organic structuring agent of the formula HO—(CH2)n—OH, with 2?n?5, at least one alkali and/or alkaline earth metal M and water and then implementing in a step (ii) hydrothermal treatment of said mixture until at least said crystallized lamellar solid is formed.
    Type: Grant
    Filed: December 14, 2007
    Date of Patent: September 20, 2011
    Assignee: IEP Energies Nouvelles
    Inventors: Emmanuelle Guillon, Nicolas Bats, Antoine Fecant
  • Patent number: 8002857
    Abstract: A process for preparation of biomass mixed with a heavy hydrocarbon fraction yields a feedstock for the purpose of supplying a gasification unit. The process comprises a first mixing stage followed by a grinding stage and makes it possible to deliver a suspension of biomass particles less than 500 microns in size that are dispersed in the heavy hydrocarbon fraction.
    Type: Grant
    Filed: June 27, 2008
    Date of Patent: August 23, 2011
    Assignee: IEP Energies Nouvelles
    Inventor: Matthieu Rolland
  • Publication number: 20110020887
    Abstract: The invention relates to a process for the enantioselective enzymatic reduction of secodione derivatives. The secodione derivative is reduced with an oxidoreductase/dehydrogenase in the presence of NADH or NADPH as a cofactor. The secodione derivative is used in the reaction batch at a concentration of ?10 g/l and the oxidized cofactor NAD or NADP formed by the oxidoreductase/dehydrogenase is regenerated continuously.
    Type: Application
    Filed: December 7, 2007
    Publication date: January 27, 2011
    Applicant: IEP GMBH
    Inventors: Antje Gupta, Anke Tschentscher, Maria Bobkova