Patents Assigned to IEP
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Patent number: 10291017Abstract: There is provided an integration of the leakage current functions of an RCD and the voltage sensing functions of other prior art protection devices. By integrating the two capabilities into one decision making system/algorithm, and considering the circuits performance in terms of leakage current as it correlated with elevated protective earth voltages (and vice versa), an embodiment is created which is able to “look into” a protected electrical system and make much more precise and discerning decisions on electrical status and probability of unsafe events. The resultant technology attends to the outstanding issues with the prior art technologies as they stand, and provides a protection solution that covers the entire range of electrical power wiring configurations and the practical complexities of modern electrical works.Type: GrantFiled: June 10, 2014Date of Patent: May 14, 2019Assignee: IEP2 RESEARCH PTY LIMITEDInventors: Richard Harris, Geoffrey Rubython
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Publication number: 20160134105Abstract: There is provided an integration of the leakage current functions of an RCD and the voltage sensing functions of other prior art protection devices. By integrating the two capabilities into one decision making system/algorithm, and considering the circuits performance in terms of leakage current as it correlated with elevated protective earth voltages (and vice versa), an embodiment is created which is able to “look into” a protected electrical system and make much more precise and discerning decisions on electrical status and probability of unsafe events. The resultant technology attends to the outstanding issues with the prior art technologies as they stand, and provides a protection solution that covers the entire range of electrical power wiring configurations and the practical complexities of modern electrical works.Type: ApplicationFiled: June 10, 2014Publication date: May 12, 2016Applicant: IEP2 RESEARCH PTY LIMITEDInventors: Richard HARRIS, Geoffrey RUBYTHON
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Patent number: 9228214Abstract: In a process for the enantioselective enzymatic reduction of a hydroxy ketone of general formula I wherein R1?C1-C6 alkyl and R2?—Cl, —CN, —OH, —H or C1-C6 alkyl, into a chiral diol of general formula II wherein R1 and R2 have the same meaning as in formula I, the hydroxy ketone is reduced with an oxidoreductase in the presence of NADH or NADPH as a cofactor, wherein a) the hydroxy ketone is provided in the reaction at a concentration of ?50 g/l, b) the oxidized cofactor NAD or NADP having formed is regenerated continuously by oxidation of a secondary alcohol of general formula RXRYCHOH, wherein RX, RY independently represent hydrogen, branched or unbranched C1-C8-alkyl and Ctotal?3, and c) the reduction of the hydroxy ketone and the oxidation of the secondary alcohol are catalyzed by the same oxidoreductase.Type: GrantFiled: February 4, 2015Date of Patent: January 5, 2016Assignee: CAMBREX IEP GMBHInventors: Antje Gupta, Maria Dupont, Anke Tschentscher
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Publication number: 20150152451Abstract: In a process for the enantioselective enzymatic reduction of a hydroxy ketone of general formula I wherein R1=C1-C6 alkyl and R2?—Cl, —CN, —OH, —H or C1-C6 alkyl, into a chiral diol of general formula II wherein R1 and R2 have the same meaning as in formula I, the hydroxy ketone is reduced with an oxidoreductase in the presence of NADH or NADPH as a cofactor, wherein a) the hydroxy ketone is provided in the reaction at a concentration of ?50 g/l, b) the oxidized cofactor NAD or NADP having formed is regenerated continuously by oxidation of a secondary alcohol of general formula RXRYCHOH, wherein RX, RY independently represent hydrogen, branched or unbranched C1-C8-alkyl and Ctotal?3, and c) the reduction of the hydroxy ketone and the oxidation of the secondary alcohol are catalyzed by the same oxidoreductase.Type: ApplicationFiled: February 4, 2015Publication date: June 4, 2015Applicant: CAMBREX IEP GMBHInventors: Antje GUPTA, Maria DUPONT, Anke TSCHENTSCHER
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Patent number: 9045780Abstract: In a process for the stereoselective, in particular enantioselective enzymatic reduction of keto compounds to the corresponding chiral hydroxy compounds, wherein the keto compounds are reduced with an enantioselective, NADH-specific oxidoreductase, a polypeptide is used for reducing the keto compounds, which polypeptide exhibits an R-ADH-signature H-[P; A]-[I; A; Q; V; L]-[G; K]-R at positions 204-208 and the following further structural features in their entirety: (i) an N-terminal Rossmann-Fold GxxxGxG, (ii) an NAG-motif at position 87, (iii) a catalytic triad consisting of S 139, Y 152 and K 156, (iv) a negatively charged amino acid moiety at position 37, (v) two C-terminal motifs in the dimerization domain [A; S]-S-F and [V; I]-DG-[G; A]-Y-[T; C; L]-[A; T; S]-[Q; V; R; L; P], (vi) Val or Leu at position 159 (4 positions downstream of K 156), (vii) Asn at position 178, and (viii) a proline moiety at position 188.Type: GrantFiled: March 3, 2010Date of Patent: June 2, 2015Assignee: IEP GMBHInventors: Antje Gupta, Maria Bobkova, Anke Tschentscher
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Patent number: 9040265Abstract: The invention relates to a process for the enantioselective enzymatic reduction of a keto compound to the corresponding chiral hydroxy compound, wherein the keto compound is reduced with an oxidoreductase in the presence of a cofactor, and is characterized in that an oxidoreductase is used which has an amino acid sequence in which (a) at least 70% of the amino acids are identical to the amino acids of one of the amino acid sequences SEQ ID No 1, SEQ ID No 6 and SEQ ID No 8, or (b) at least 55% of the amino acids are identical to the amino acids of the amino acid sequence SEQ ID No 2, or (c) at least 65% of the amino acids are identical to the amino acids of the amino acid sequence SEQ ID No 3, or (d) at least 75% of the amino acids are identical to the amino acids of the amino acid sequence SEQ ID No 4, or (e) at least 65% of the amino acids are identical to the amino acids of the amino acid sequence SEQ ID No 5, or (0 at least 50% of the amino acids are identical to the amino acids of the amino acid sequenceType: GrantFiled: October 25, 2011Date of Patent: May 26, 2015Assignee: IEP GMBHInventors: Anke Tschentscher, Antje Gupta, Maria Bobkova
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Patent number: 8980592Abstract: In a process for the enantioselective enzymatic reduction of a hydroxy ketone of general formula I wherein R1=C1-C6 alkyl and R2=—Cl, —CN, —OH, —H or C1-C6 alkyl, into a chiral diol of general formula II wherein R1 and R2 have the same meaning as in formula I, the hydroxy ketone is reduced with an oxidoreductase in the presence of NADH or NADPH as a cofactor, wherein a) the hydroxy ketone is provided in the reaction at a concentration of ?50 g/l, b) the oxidized cofactor NAD or NADP having formed is regenerated continuously by oxidation of a secondary alcohol of general formula RXRYCHOH, wherein RX, RY independently represent hydrogen, branched or unbranched C1-C8-alkyl and Ctotal?3, and c) the reduction of the hydroxy ketone and the oxidation of the secondary alcohol are catalyzed by the same oxidoreductase.Type: GrantFiled: December 14, 2006Date of Patent: March 17, 2015Assignee: Cambrex IEP GmbHInventors: Antje Gupta, Maria Bobkova, Anke Tschentscher
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Patent number: 8953288Abstract: A protection system for an IT electrical distribution system (EDS) has a floating reference conductor and two electrical conductors in the form of an active conductor and a neutral conductor. System includes two input terminals for electrically connecting to an MEN electrical power source that is upstream of system. Two output terminals are electrically connected to an electrical load in the form of an electrical motor for a compressor of an upright freezer display. A motor protection device, in the form of an MCB, electrically connects terminals to allow a supply of electrical power to a motor. The MCB is responsive to a fault signal at a port for selectively electrically disconnecting at least one of the terminals. A sentinel unit selectively generates the fault signal at port in response to the current in conductor being greater than a predetermined threshold.Type: GrantFiled: December 21, 2009Date of Patent: February 10, 2015Assignee: IEP2 Research Pty LimitedInventors: David Paul Jankowski, Geoffrey Rubython, Wayne Callen, Walter Henry Berryman
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Patent number: 8953295Abstract: A protection system for an IT electrical distribution system (EDS) has a floating reference conductor and two electrical conductors in the form of an active conductor and a neutral conductor. System includes two input terminals for electrically connecting to an MEN electrical power source that is upstream of system. Two output terminals are electrically connected to an electrical load in the form of an electrical motor for a compressor of an upright freezer display. Motor is downstream of the system. A protection device, in the form of an MCB, electrically connects terminals to allow a supply of electrical power from source to motor. MCB is responsive to a fault signal at a port for selectively electrically disconnecting at least one of terminals to prevent the supply of electrical power. A sentinel unit selectively generates the fault signal at port in response to the current in conductor being greater than a predetermined threshold.Type: GrantFiled: December 21, 2009Date of Patent: February 10, 2015Assignee: IEP2 Research Pty LimitedInventors: David Paul Jankowski, Geoffrey Rubython, Wayne Callen, Walter Henry Berryman
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Patent number: 8932835Abstract: A process for the enantioselective enzymatic reduction of a keto compound of general formula I wherein R may represent any protective group for amino functions (tert. butyloxycarbonyl group (BOC), benzyloxycarbonyl group, 9-fluorenylmethoxycarbonyl group) and X?—Cl, —CN, —OH, Br, F.Type: GrantFiled: September 22, 2008Date of Patent: January 13, 2015Assignee: IEP GmbHInventors: Antje Gupta, Maria Bobkova, Anke Tschentscher
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Publication number: 20140175334Abstract: The invention concerns a capture mass for capturing heavy metals in a liquid or gaseous effluent, comprising a porous solid support, copper sulphide and at least one second metal sulphide the metal of which is selected from the group constituted by chromium, manganese, iron, cobalt and nickel, and in which the ratio of the percentage by weight of the metal or metals other than copper to the percentage by weight of copper is in the range 0.01 to 2. The invention also concerns a process for preparing said capture mass and a process for capturing heavy metals in a gaseous or liquid effluent, in which said effluent is brought into contact with said capture mass.Type: ApplicationFiled: December 17, 2013Publication date: June 26, 2014Applicant: IEP Energies nouvellesInventors: Fabien PORCHERON, Arnaud BAUDOT, Karin BARTHELET
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Patent number: 8361765Abstract: The invention relates to an enzymatic method for the enantioselective reduction of organic keto compounds to the corresponding chiral hydroxy compounds, an alcohol dehydrogenase from Lactobacillus minor and a method for the enantioselective production of (S)-hydroxy compounds from a racemate.Type: GrantFiled: June 19, 2007Date of Patent: January 29, 2013Assignee: IEP GmbHInventors: Antje Gupta, Klaus Breese, Gert Bange, Peter Neubauer
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Patent number: 8323936Abstract: The invention relates to a process for the enantioselective enzymatic reduction of secodione derivatives. The secodione derivative is reduced with an oxidoreductase/dehydrogenase in the presence of NADH or NADPH as a cofactor. The secodione derivative is used in the reaction batch at a concentration of ?10 g/l and the oxidized cofactor NAD or NADP formed by the oxidoreductase/dehydrogenase is regenerated continuously.Type: GrantFiled: September 7, 2011Date of Patent: December 4, 2012Assignee: IEP GmbHInventors: Antje Gupta, Anke Tschentscher, Maria Bobkova
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Patent number: 8227208Abstract: A process for the enantioselective reduction of compounds having a steroid structure (ABCD) including one or several heteroatoms, one or several double bonds and/or aromatic components in the ring structure and having at least one oxo group at positions 3, 7, 11, 12 or 17 in the steroid ring system or in the a-position of any carbon moiety of the steroid structure: comprising providing the oxosteroid compound in the reaction at a concentration of ?50 g/L, a reduced cofactor NADH or NADPH, a hydroxysteroid dehydrogenase and a secondary alcohol or cycloalknaol to effect the enantioselective reduction.Type: GrantFiled: April 11, 2007Date of Patent: July 24, 2012Assignee: IEP GmbHInventors: Antje Gupta, Anke Tschentscher, Maria Bobkova
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Patent number: 8158406Abstract: The present invention relates to a process for the enantioselective enzymatic reduction of keto compounds, in particular of 4-halo-3-oxobutyric acid esters, to the corresponding R-alcohols or S-4-halo-3-hydroxybutyric acid esters, respectively, using an R-specific oxidoreductase in the presence of a cofactor.Type: GrantFiled: February 21, 2006Date of Patent: April 17, 2012Assignee: IEP GmbHInventors: Antje Gupta, Maria Bobkova, Anke Tschentscher
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Publication number: 20120040425Abstract: In a process for the stereoselective, in particular enantioselective enzymatic reduction of keto compounds to the corresponding chiral hydroxy compounds, wherein the keto compounds are reduced with an enantioselective, NADH-specific oxidoreductase, a polypeptide is used for reducing the keto compounds, which polypeptide exhibits an R-ADH-signature H-[P; A]-[I; A; Q; V; L]-[G; K]-R at positions 204-208 and the following further structural features in their entirety: (i) an N-terminal Rossmann-Fold GxxxGxG, (ii) an NAG-motif at position 87, (iii) a catalytic triad consisting of S 139, Y 152 and K 156, (iv) a negatively charged amino acid moiety at position 37, (v) two C-terminal motifs in the dimerization domain [A; S]-S-F and [V; I]-DG-[G; A]-Y-[T; C; L]-[A; T; S]-[Q; V; R; L; P], (vi) Val or Leu at position 159 (4 positions downstream of K 156), (vii) Asn at position 178, and (viii) a proline moiety at position 188.Type: ApplicationFiled: March 3, 2010Publication date: February 16, 2012Applicant: IEP GMBHInventors: Antje Gupta, Maria Bobkova, Anke Tschentscher
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Publication number: 20120040424Abstract: The invention relates to a process for the enantioselective enzymatic reduction of secodione derivatives. The secodione derivative is reduced with an oxidoreductase/dehydrogenase in the presence of NADH or NADPH as a cofactor. The secodione derivative is used in the reaction batch at a concentration of ?10 g/l and the oxidized cofactor NAD or NADP formed by the oxidoreductase/dehydrogenase is regenerated continuously.Type: ApplicationFiled: September 7, 2011Publication date: February 16, 2012Applicant: IEP GMBHInventors: Antje GUPTA, Anke TSCHENTSCHER, Maria BOBKOVA
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Patent number: 8021637Abstract: Described is a process for the preparation of at least one crystallized lamellar solid formed by magadiite or kenyaite consisting of implementing in a step (i) mixing of at least one silica source, at least one organic structuring agent of the formula HO—(CH2)n—OH, with 2?n?5, at least one alkali and/or alkaline earth metal M and water and then implementing in a step (ii) hydrothermal treatment of said mixture until at least said crystallized lamellar solid is formed.Type: GrantFiled: December 14, 2007Date of Patent: September 20, 2011Assignee: IEP Energies NouvellesInventors: Emmanuelle Guillon, Nicolas Bats, Antoine Fecant
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Patent number: 8002857Abstract: A process for preparation of biomass mixed with a heavy hydrocarbon fraction yields a feedstock for the purpose of supplying a gasification unit. The process comprises a first mixing stage followed by a grinding stage and makes it possible to deliver a suspension of biomass particles less than 500 microns in size that are dispersed in the heavy hydrocarbon fraction.Type: GrantFiled: June 27, 2008Date of Patent: August 23, 2011Assignee: IEP Energies NouvellesInventor: Matthieu Rolland
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Publication number: 20110020887Abstract: The invention relates to a process for the enantioselective enzymatic reduction of secodione derivatives. The secodione derivative is reduced with an oxidoreductase/dehydrogenase in the presence of NADH or NADPH as a cofactor. The secodione derivative is used in the reaction batch at a concentration of ?10 g/l and the oxidized cofactor NAD or NADP formed by the oxidoreductase/dehydrogenase is regenerated continuously.Type: ApplicationFiled: December 7, 2007Publication date: January 27, 2011Applicant: IEP GMBHInventors: Antje Gupta, Anke Tschentscher, Maria Bobkova