Patents Assigned to Igenomix S.L.
  • Stem cell therapy in endometrial pathologies
    Patent number: 11129851
    Abstract: The invention generally relates to the ability of autologous CD133+ bone marrow stem cells (BMDSC) to induce endometrial regeneration and treat endometrial pathologies such as Asherman's syndrome and endometrial atrophy. Methods to induce endometrial regeneration are provided, which comprises administering an effective amount of autologous CD133+ bone marrow derived stem cells (BMDSC) into uterine arteries of a subject in need thereof to induce endometrial regeneration.
    Type: Grant
    Filed: June 5, 2015
    Date of Patent: September 28, 2021
    Assignee: IGENOMIX S.L.
    Inventors: Carlos Simón, Xavier Santamaria, Irene Cervelló, Antonio Pellicer
  • METHODS AND DEVICES FOR DETECTING BIOMARKERS ASSOCIATED WITH PREECLAMPSIA
    Publication number: 20200271660
    Abstract: Provided herein, in some embodiments, are methods and compositions for detecting differentially expressed genes in a sample obtained from a subject having or at risk for preeclampsia.
    Type: Application
    Filed: September 5, 2018
    Publication date: August 27, 2020
    Applicant: IGENOMIX S.L.
    Inventors: Carlos Simon, Susan Fisher, Tamara Garrido
  • GENE EXPRESSION PROFILE AS AN ENDOMETRIAL RECEPTIVITY MARKER
    Publication number: 20190276890
    Abstract: The present invention relates to determining the receptivity of human endometrium from a gene expression profile. More specifically, the invention consists of developing a specific expression microarray of endometrial receptivity (Endometrial Receptivity Array or ERA) which allows evaluating the receptive state of a human endometrium, as well as assessing said state for diagnostic and therapeutic purposes.
    Type: Application
    Filed: September 24, 2018
    Publication date: September 12, 2019
    Applicant: IGENOMIX S.L.
    Inventors: Carlos Simón Vallés, José Horcajadas Almansa, Patricia Diaz Gimeno, Antonio Pellicer Martínez
  • Gene expression profile as an endometrial receptivity marker
    Patent number: 10081840
    Abstract: The present invention relates to determining the receptivity of human endometrium from a gene expression profile. More specifically, the invention consists of developing a specific expression microarray of endometrial receptivity (Endometrial Receptivity Array or ERA) which allows evaluating the receptive state of a human endometrium, as well as assessing said state for diagnostic and therapeutic purposes.
    Type: Grant
    Filed: July 22, 2009
    Date of Patent: September 25, 2018
    Assignee: Igenomix S.L.
    Inventors: Carlos Simón Vallés, José Antonio Horcajadas Almansa, Patricia Díaz Gimeno, Antonio Pellicer Martínez
  • STEM CELL THERAPY IN ENDOMETRIAL PATHOLOGIES
    Publication number: 20170128492
    Abstract: The invention generally relates to the ability of autologous CD133+ bone marrow stem cells (BMDSC) to induce endometrial regeneration and treat endometrial pathologies such as Asherman's syndrome and endometrial atrophy. Methods to induce endometrial regeneration are provided, which comprises administering an effective amount of autologous CD133+ bone marrow derived stem cells (BMDSC) into uterine arteries of a subject in need thereof to induce endometrial regeneration.
    Type: Application
    Filed: June 5, 2015
    Publication date: May 11, 2017
    Applicant: Igenomix S.L.
    Inventors: Carlos Simón, Xavier Santamaria, Irene Cervelló, Antonio Pellicer
  • EARLY DETECTION OF PREECLAMPSIA
    Publication number: 20170097358
    Abstract: The invention provides non-invasive assays to reliably identify women who have or are predisposed to developing preeclampsia (PE). The method comprises measuring a level of annexin A2 (ANXA2) in a test sample obtained of a subject; and identifying the subject as having preeclampsia or at an increased risk of developing preeclampsia when the level of ANXA2 in the test sample is decreased in relation to a control sample. Methods to treat subject identified as having PE or at an increased risk of developing preeclampsia are also provided.
    Type: Application
    Filed: March 19, 2015
    Publication date: April 6, 2017
    Applicant: Igenomix S.L.
    Inventors: Carlos Simón, Tamara Garrido, Antonio Pellicer