Patents Assigned to Ikaria Development Subsidiary One LLC
  • Process for Manufacturing Partially Cross-Linked Alginate Solution
    Publication number: 20130165403
    Abstract: Described is a microfluidic process for manufacturing partially cross-linked alginate solution, wherein the alginate solution is a homogenous liquid which exhibits an elastic response (G?) which is equal to or greater than its viscous response (G?). In particular, the process may comprise microfluidic mixing of sodium alginate and calcium gluconate solutions to provide an injectable partially cross-linked alginate solution.
    Type: Application
    Filed: December 21, 2012
    Publication date: June 27, 2013
    Applicant: Ikaria Development Subsidiary One LLC
    Inventor: Ikaria Development Subsidiary One LLC
  • Labeled Alginate Conjugates for Molecular Imaging Applications
    Publication number: 20130149242
    Abstract: Described are bifunctional NOTA-based derivatives capable of conjugating with alginate and with metal ions, as well as NOTA-alginate conjugates which can be labeled with stable or radioactive metal ions. Also described are conjugation methods of the bifunctional NOTA-based linker with alginate, and methods of using radiometal-labeled NOTA-alginate conjugates or other radio-labeled alginate conjugates as imaging reagents.
    Type: Application
    Filed: December 7, 2012
    Publication date: June 13, 2013
    Applicant: Ikaria Development Subsidiary One LLC
    Inventor: Ikaria Development Subsidiary One LLC