Patents Assigned to Iketon Farmaceutici, S.r.l.
  • Supersulfated heparins
    Patent number: 5164378
    Abstract: A process for the depolymerization and supersulfation of heparin and the so obtained supersulfated heparins are disclosed. The process comprises treating heparin with oleum containing from 2 to 6% free sulfuric anhydride at a temperature from -10.degree. to +20.degree. C. The obtained heparins have molecular weights from 2000 to 5000 and a sulfation degree from 3.4 to 4.3. All of them are endowed with a remarkable antithrombotic activity.
    Type: Grant
    Filed: November 26, 1990
    Date of Patent: November 17, 1992
    Assignee: Iketon Farmaceutici, S.r.l.
    Inventors: Renato Conti, Paolo Casati, Maria B. Gorini, Antonio Maggi