Abstract: A method for automated microscopic analysis wherein the test protocol is obtained from interrogatable data affixed to each microscope slide. The method further comprises the algorithms that implement the test protocol.
Type:
Application
Filed:
July 29, 2014
Publication date:
January 28, 2016
Applicant:
Ikonisys, Inc.
Inventors:
Youngmin Kim, Yanning ZHU, Yash AGARWAL, Xiuzhong WANG, Aaron ARMSTRONG, Robert BORGERDING, Andrew MACGINITIE, Antti SEPPO, Ilia JCHETOVKIN, Michael KILPATRICK, Petros TSIPOURAS, Triantafyllos P. TAFAS
Abstract: An improved filter wheel is disclosed, through embodiments, that comprises a plurality of reflector support structures formed as a unitized structure with a circular base member. In some embodiments, the filter wheel further comprises a plurality of light sources mounted on the filter wheel.
Abstract: A system for automated microscopic analysis of a plurality of data-encoded microscope slides that provides that data written to or read from the slides may include images, analysis protocols, analytic results and other pertinent data. The system may also encompass a magazine that contains a plurality of data encoded slides.
Abstract: A method for automated microscopic analysis wherein the test protocol is obtained from interrogatable data affixed to each microscope slide. The method further comprises the algorithms that implement the test protocol.
Type:
Grant
Filed:
August 3, 2007
Date of Patent:
July 29, 2014
Assignee:
Ikonisys, Inc.
Inventors:
Young Min Kim, Yanning Zhu, Yash Agarwal, Xiuzhong Wang, Aaron Armstrong, Robert Borgerding, Andrew Macginitie, Antti Seppo, Ilia Ichetovkin, Michael Kilpatrick, Petros Tsipouras, Triantafyllos P. Tafas
Abstract: An improved filter wheel is disclosed, through embodiments, that comprises a plurality of reflector support structures formed as a unitized structure with a circular base member. In some embodiments, the filter wheel further comprises a plurality of light sources mounted on the filter wheel.
Abstract: An filter, apparatus and method for preparing microscope slides is presented. After filtration of the specimen is performed, the filter containing the filtrand is configured to be microscopically examined. The filter may either be affixed to a microscope slide or, in an embodiment, the filter may be incorporated into a microscope slide.
Type:
Grant
Filed:
July 9, 2010
Date of Patent:
May 6, 2014
Assignee:
Ikonisys, Inc.
Inventors:
Michael Thomas, Charles Climer, Richard Schlueter, Triantafyllos P. Tafas, Michael Kilpatrick, Antti Seppo
Abstract: An improved filter wheel is disclosed, through embodiments, that comprises a plurality of reflector support structures formed as a unitized structure with a circular base member. In some embodiments, the filter wheel further comprises a plurality of light sources mounted on the filter wheel.
Abstract: A method for providing quantitative information regarding the extent of infection of host cells by an infectious agent. A microscope image of a specimen of a bodily fluid is analyzed using image processing techniques to quantify the percentage of the area of the specimen that is infected.
Type:
Application
Filed:
February 22, 2013
Publication date:
June 27, 2013
Applicant:
Ikonisys, Inc.
Inventors:
Triantafyllos P. Tafas, Michael Kilpatrick, Petros Tsipouras
Abstract: An automated, highly sensitive, specific and potentially quantitative detection method using an automated microscope for identifying and enumerating rare cancer cells in blood and other fluids.
Type:
Grant
Filed:
December 27, 2011
Date of Patent:
May 21, 2013
Assignee:
Ikonisys, Inc.
Inventors:
Sir Walter Bodmer, Triantafyllos P. Tafas, Michael Kilpatrick, Petros Tsipouras, Xiuzhong Wang, Youngmin Kim, Michael Thomas, Antti Seppo, Triantafyllia Ntouroupi, Changhua Yu, Charles Climer
Abstract: A method for detecting and quantitating multiple and unique fluorescent signals from a cell sample is provided. The method combines immunohistochemistry and a fluorescent-labeled in situ hybridization techniques. The method is useful for identifying specific subcellular components of cells such as chromosomes and proteins.
Type:
Application
Filed:
November 15, 2012
Publication date:
March 28, 2013
Applicant:
Ikonisys, Inc.
Inventors:
Michael Kilpatrick, Triantafyllos P. Tafas
Abstract: An improved filter wheel is disclosed, through embodiments, that comprises a plurality of reflector support structures formed as a unitized structure with a circular base member. In some embodiments, the filter wheel further comprises a plurality of light sources mounted on the filter wheel.
Abstract: A method for detecting and quantitating multiple and unique fluorescent signals from a cell sample is provided. The method combines immunohistochemistry and a fluorescent-labeled in situ hybridization techniques. The method is useful for identifying specific subcellular components of cells such as chromosomes and proteins.
Type:
Application
Filed:
March 14, 2011
Publication date:
March 29, 2012
Applicant:
Ikonisys, Inc.
Inventors:
Michael Kilpatrick, Triantafyllos Tafas
Abstract: A method for providing quantitative information regarding the extent of infection of host cells by an infectious agent. A microscope image of a specimen of a bodily fluid is analyzed using image processing techniques to quantify the percentage of the area of the specimen that is infected.
Type:
Application
Filed:
July 22, 2011
Publication date:
January 26, 2012
Applicant:
Ikonisys, Inc.
Inventors:
Triantafyllos TAFAS, Michael KILPATRICK, Petros TSIPOURAS
Abstract: An automated, highly sensitive, specific and potentially quantitative detection method using an automated microscope for identifying and enumerating rare cancer cells in blood and other fluids.
Type:
Grant
Filed:
November 13, 2008
Date of Patent:
January 3, 2012
Assignee:
Ikonisys, Inc.
Inventors:
Sir Walter Bodmer, Triantafyllos Tafas, Michael Kilpatrick, Petros Tsipouras, Xiuzhong Wang, Youngmin Kim, Michael Thomas, Antti Seppo, Triantafyllia Ntouroupi, Changhua Yu, Charles Climer
Abstract: An embodiment is disclosed for performing the image processing for analyzing the results of a fluorescence in situ hybridization (FISH) microscopic automated sample analysis to determine specific chromosomal characteristics.
Type:
Application
Filed:
July 12, 2011
Publication date:
December 29, 2011
Applicant:
IKonisys, Inc.
Inventors:
Yanning Zhu, Triantafyllos Tafas, Youngmin Kim, Xiuzhong Wang
Abstract: An improved filter wheel is disclosed, through embodiments, that comprises a plurality of reflector support structures formed as a unitized structure with a circular base member. In some embodiments, the filter wheel further comprises a plurality of light sources mounted on the filter wheel.
Abstract: A method for recognizing an object in an image is disclosed wherein a fractal map of the image is generated by estimating the fractal dimension of each pixel in the image. The fractal map may be segmented by thresholding and locations of candidate objects are determined. The pixel value of the image pixel corresponding to the same location where the candidate object is found in the fractal map may be compared to a threshold value. If the pixel value is greater than the threshold value, the candidate object is recognized as a valid object.
Type:
Grant
Filed:
February 7, 2011
Date of Patent:
August 2, 2011
Assignee:
Ikonisys Inc.
Inventors:
Triantafyllos P. Tafas, Michael Kilpatrick, Petros Tsipouras
Abstract: A method for recognizing an object in an image is disclosed wherein a fractal map of the image is generated by estimating the fractal dimension of each pixel in the image. The fractal map may be segmented by thresholding and locations of candidate objects are determined. The pixel value of the image pixel corresponding to the same location where the candidate object is found in the fractal map may be compared to a threshold value. If the pixel value is greater than the threshold value, the candidate object is recognized as a valid object.
Type:
Application
Filed:
February 7, 2011
Publication date:
June 2, 2011
Applicant:
Ikonisys, Inc.
Inventors:
Triantafyllos Tafas, Michael Kilpatrick, Petros Tsipouras
Abstract: An automated cassette and slide handling system is disclosed which organizes microscope slides in cassettes, automatically and sequentially removes individual slides from their respective cassettes, positioned each slide under the microscope as provided by the protocol, and after examination returns the slide to its proper cassette.
Type:
Grant
Filed:
August 3, 2007
Date of Patent:
May 24, 2011
Assignee:
Ikonisys, Inc.
Inventors:
Tibor Virag, Yash Agarwal, Wei Guo, Richard Eberle, Youngmin Kim, Michael Kilpatrick, Petros Tsipouras, Triantafyllos Tafas