Patents Assigned to ImaginAb, Inc.
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Patent number: 11266745Abstract: Provided herein are diabodies that comprise extension sequences and antigen binding constructs that comprise extension sequences.Type: GrantFiled: January 10, 2018Date of Patent: March 8, 2022Assignee: ImaginAb, Inc.Inventors: Jean Marie Gudas, Daulet Kadyl Satpayev, Tove Olafsen, Alessandro Mascioni, Michael Yuri Torgov
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Patent number: 11254744Abstract: Antigen binding constructs that bind to desired targets are disclosed, for example antibodies, including antibody fragments (such as scFv and minibodies) that bind to a target molecule, and have one or more of the disclosed hinges are described herein. Methods of use are described herein.Type: GrantFiled: August 4, 2016Date of Patent: February 22, 2022Assignee: IMAGINAB, INC.Inventors: Chio Mui Chan, Jean Gudas, Tove Olafsen, Daulet Kadyl Satpayev, Michael Yuri Torgov
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Patent number: 11203639Abstract: Antigen binding constructs that bind to desired targets are disclosed, for example antibodies, including antibody fragments (such as scFv and minibodies) that bind to a target molecule, and have one or more of the disclosed hinges are described herein. Methods of use are described herein.Type: GrantFiled: August 4, 2016Date of Patent: December 21, 2021Assignee: IMAGINAB, INC.Inventors: Chio Mui Chan, Jean Gudas, Tove Olafsen, Daulet Kadyl Satpayev, Michael Yuri Torgov
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Patent number: 11180570Abstract: In one embodiment, a minibody monomer that binds PSMA is provided. The minibody monomer is encoded by a nucleotide sequence comprising, from N-terminus to C-terminus, an scFv sequence that can bind PSMA, an artificial hinge sequence, and a human IgG CH3 sequence. In another embodiment, a CysDB monomer that binds PSMA is provided. The CysDB monomer may be encoded by a nucleotide sequence comprising, from N-terminus to C-terminus, an scFv sequence that can bind PSMA and a cysteine tail. In other embodiments, methods for diagnosing or treating a cancer associated with PSMA expression in a subject are provided.Type: GrantFiled: February 12, 2019Date of Patent: November 23, 2021Assignee: ImaginAb, Inc.Inventors: David T. Ho, Tove Olafsen, Arye Lipman
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Patent number: 10882909Abstract: Antigen binding constructs that bind to CD3, for example antibodies, including antibody fragments (such as minibodies and cys-diabodies) that bind to CD3, are described herein. Methods of use are described herein.Type: GrantFiled: April 25, 2019Date of Patent: January 5, 2021Assignee: ImaginAb, Inc.Inventors: David T. Ho, Tove Olafsen, Jason Romero, Christian P. Behrenbruch
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Patent number: 10414820Abstract: Antigen binding constructs that bind to CD8, for example antibodies, including antibody fragments (such as scFv, minibodies, and cys-diabodies) that bind to CD8, are described herein. Methods of use are described herein.Type: GrantFiled: March 10, 2014Date of Patent: September 17, 2019Assignee: IMAGINAB, INC.Inventors: David T. Ho, Tove Olafsen, Giti Agahi, Christian P. Behrenbruch
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Patent number: 10377826Abstract: Antigen binding constructs that bind to CD8, for example antibodies, including antibody fragments (such as scFv, minibodies, and cys-diabodies) that bind to CD8, are described herein. Methods of use are described herein.Type: GrantFiled: August 5, 2016Date of Patent: August 13, 2019Assignee: IMAGINAB, INC.Inventors: David T. Ho, Tove Olafsen, Giti Agahi, Christian P. Behrenbruch
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Patent number: 10301389Abstract: Antigen binding constructs that bind to CD3, for example antibodies, including antibody fragments (such as minibodies and cys-diabodies) that bind to CD3, are described herein. Methods of use are described herein.Type: GrantFiled: June 13, 2013Date of Patent: May 28, 2019Assignee: IMAGINAB, INC.Inventors: David T. Ho, Tove Olafsen, Jason Romero, Christian P. Behrenbruch
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Patent number: 10072080Abstract: Antigen binding constructs that bind to CD8, for example antibodies, including antibody fragments (such as scFv, minibodies, and cys-diabodies) that bind to CD8, are described herein. Methods of use are described herein.Type: GrantFiled: August 5, 2016Date of Patent: September 11, 2018Assignee: ImaginAB, Inc.Inventors: David T. Ho, Tove Olafsen, Giti Agahi, Christian P. Behrenbruch
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Publication number: 20140271462Abstract: Antigen binding constructs that bind to CD8, for example antibodies, including antibody fragments (such as scFv, minibodies, and cys-diabodies) that bind to CD8, are described herein. Methods of use are described herein.Type: ApplicationFiled: March 10, 2014Publication date: September 18, 2014Applicant: IMAGINAB, INC.Inventors: David T. Ho, Tove Olafsen, Giti Agahi, Christian P. Behrenbruch
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Publication number: 20140234215Abstract: In one embodiment, a minibody monomer that binds PSMA is provided. The minibody monomer is encoded by a nucleotide sequence comprising, from N-terminus to C-terminus, an scFv sequence that can bind PSMA, an artificial hinge sequence, and a human IgG CH3 sequence. In another embodiment, a CysDB monomer that binds PSMA is provided. The CysDB monomer may be encoded by a nucleotide sequence comprising, from N-terminus to C-terminus, an scFv sequence that can bind PSMA and a cysteine tail. In other embodiments, methods for diagnosing or treating a cancer associated with PSMA expression in a subject are provided.Type: ApplicationFiled: April 30, 2014Publication date: August 21, 2014Applicant: ImaginAb, Inc.Inventors: David T. Ho, Tove Olafsen, Arye Lipman
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Patent number: 8772459Abstract: In one embodiment, a minibody monomer that binds PSMA is provided. The minibody monomer is encoded by a nucleotide sequence comprising, from N-terminus to C-terminus, an scFv sequence that can bind PSMA, an artificial hinge sequence, and a human IgG CH3 sequence. In another embodiment, a CysDB monomer that binds PSMA is provided. The CysDB monomer may be encoded by a nucleotide sequence comprising, from N-terminus to C-terminus, an scFv sequence that can bind PSMA and a cysteine tail. In other embodiments, methods for diagnosing or treating a cancer associated with PSMA expression in a subject are provided.Type: GrantFiled: December 2, 2010Date of Patent: July 8, 2014Assignee: ImaginAb, Inc.Inventors: David Ho, Tove Olafsen, Arye Lipman