Abstract: An improved method for detecting tumor cell invasion using diffusion times as short as two (2) msec incorporates diffusion weighing imaging techniques into a standard spin echo (SE) pulse sequence to minimize the effects of compartment boundary restrictions on diffusion values and corresponding MRI imaging data related to glioma invasion.
Type:
Application
Filed:
May 22, 2008
Publication date:
November 25, 2010
Applicant:
IMAGING BIOMETRICS, LLC
Inventors:
Kathleen Schmainda, Eric S. Paulson, Douglas E. Prah
Abstract: A magnetic resonance imaging (MRI) methodology is provided for simultaneous measurement of dynamic susceptibility contrast (DSC) MRI and dynamic contrast enhanced (DCE) MRI perfusion and permeability parameters using a combination of dual echo and spiral acquisition techniques with no contrast agent preload. T1 and T2/T2* leakage effects are eliminated, thereby permitting accurate measurement of blood volume, blood flow and vascular permeability which are used in evaluating tumor angiogenesis.
Type:
Application
Filed:
May 22, 2008
Publication date:
November 25, 2010
Applicant:
IMAGING BIOMETRICS, LLC
Inventors:
Kathleen Schmainda, Eric S. Paulson, Douglas E. Prah