Patents Assigned to IMBA—INSIIIUT FÜR MOLEKULARE BIOTECHNOLOGIE GMBH
  • Nucleic acid modification and identification method
    Patent number: 11299779
    Abstract: A method of identifying a polynucleic acid (PNA) is presented, including the steps of providing a PNA; modifying one or more nucleobases of the PNA by addition or removal of a hydrogen bonding partner, thereby altering the base pairing capacity of the one or more nucleobases; base pairing a complementary nucleic acid to the PNA, including base pairing to at least one modified nucleobase; identifying the sequence of the complementary nucleic acid at least at the position that is complementary to at least one modified nucleobase.
    Type: Grant
    Filed: April 13, 2018
    Date of Patent: April 12, 2022
    Assignee: IMBA—INSIIIUT FÜR MOLEKULARE BIOTECHNOLOGIE GMBH
    Inventors: Stefan L. Ameres, Brian Reichholf, Veronika A. Herzog, Johannes Zuber, Matthias Muhar