Patents Assigned to Imedex
  • Patent number: 5654290
    Abstract: Drug compositions comprised of therapeutically effective amounts of at least one compound selected from the group consisting of:DHA esterified in the form of lysophosphatidyl-choline (lyso-PCDHA) in position sn-2;DHA-phosphatidylcholines (PCDHAs) in which DHA is esterified in position sn-2 and which have an acyl group of [very short length] 2 to 6 carbon atoms in position sn-1;and triglycerides in which DHA is esterified in position sn-2 and which have acyl groups of [very short length] 2 to 6 carbon atoms in positions sn-1 and sn-3.
    Type: Grant
    Filed: September 21, 1994
    Date of Patent: August 5, 1997
    Assignees: Institut National de la Sante et de la Recherche Medicale, Imedex
    Inventors: Yves Bayon, Martine Croset, Michel Lagarde, Jean Lecerf, Frank Thies, Jean-Louis Tayot, Veronique Chirouze
  • Patent number: 5618551
    Abstract: The invention relates to a biocompatible, bioresorbable and non-toxic adhesive composition for surgical use, for the bonding, in particular, of biological tissues to one another or in an implanted biomaterial, characterized in that it comprises a reactive acidic solution of non-crosslinked and potentially crosslinkable collagen or gelatin modified by oxidative cleavage, at a concentration which is preferably between approximately 5 and 30 by weight. It also relates to reactive acidic solutions and powders based on non-crosslinked collagen or gelatin modified by oxidative cleavage which are used as intermediate products in the preparation of the above-mentioned composition, and to the process for their preparation. It also relates to adhesive kits which comprise, on the one hand, the above-mentioned reactive acidic solution and, on the other hand, a neutralizing solution and which are intended for extemporaneous mixing.
    Type: Grant
    Filed: January 20, 1995
    Date of Patent: April 8, 1997
    Assignee: Imedex
    Inventors: Michel Tardy, J er ome Tiollier, Jean-Louis Tayot
  • Patent number: 5496872
    Abstract: The invention relates to an adhesive, biocompatible, biodegradable and non-toxic composition for surgical use, in particular for binding tissues, which composition is of the following general formula: ##STR1## in which: R is a hydrocarbon chain containing from 1 to 50 carbon atoms,R.sub.1 and R.sub.2 are identical or different and are chosen from the following groups: ##STR2## R.sub.3, R.sub.4, R.sub.5, R.sub.6 and R.sub.
    Type: Grant
    Filed: July 19, 1994
    Date of Patent: March 5, 1996
    Assignee: Imedex
    Inventors: Alain Constancis, Ge/ rard Soula, Jean-Louis Tayot, Je/ ro/ me Tiollier
  • Patent number: 5436135
    Abstract: Human or animal placenta is subjected to moderate enzymatic digestion, in particular with pepsin at an acid pH, then, after separation of the residual tissue the impurities are separated at a moderately acid pH, the collagen is precipitated at a neutral pH, redissolved and the residual impurities precipitated at an acid pH. The collagen obtained can be brought back to a neutral pH and dried in the form of fibres. Completely transparent, physiological and hemocompatible gels and solutions can be prepared. Applications for the fabrication of contact lenses and implants.
    Type: Grant
    Filed: January 7, 1991
    Date of Patent: July 25, 1995
    Assignees: Pasteur Merieux Serums et Vaccins, Imedex
    Inventors: Jean-Louis Tayot, Michel Tardy
  • Patent number: 5201745
    Abstract: A patch for visceral surgery is made from a biomaterial consisting of two layers of collagen superimposed and closely combined, namely a porous adhesive layer of fibrous collagen and a film of collagen and/or gelatin.
    Type: Grant
    Filed: August 15, 1991
    Date of Patent: April 13, 1993
    Assignee: Imedex
    Inventors: Jean-Louis Tayot, Jacques Marescaux, Henri Dumas, Michel Tardy
  • Patent number: 5108908
    Abstract: A process for pigments such as the treatment of proteinic solutions containing heminic groups or chlorophylls in view of their decolorization, and products thus obtained.The proteinic solution is subjected in a first step, to a slight enzymatic hydrolysis, preferably with acid pH pepsin, and the partially hydrolyzed solution is then brought to a temperature above 60.degree. C., at an acid pH between 2 and 4.
    Type: Grant
    Filed: September 14, 1990
    Date of Patent: April 28, 1992
    Assignees: Imedex, Dibevial
    Inventors: Jacques Coves, Jean-Louis Tayot
  • Patent number: 4931546
    Abstract: Collagen is submitted to a controlled oxidation by treatment with a solution of periodic acid or of a periodate, notably of sodium. Application to gels, implants, lenses, films, spheres, etc., of collagen.
    Type: Grant
    Filed: July 13, 1987
    Date of Patent: June 5, 1990
    Assignees: Imedex, Institut Merieux
    Inventors: Michel Tardy, Jean-Louis Tayot