Abstract: The present invention relies on the affinity of stressed or apoptotic cells for exogenously administered annexin V to create a multi-functional molecular probe that can be simultaneously used for imaging (localization of unstable plaque within the body) and therapy (treatment of unstable plaque).
Type:
Application
Filed:
September 6, 2002
Publication date:
August 14, 2003
Applicant:
IMETRIX, INC.
Inventors:
Francis G. Blankenberg, Jagat Narula, H. William Strauss, Vartan Ghazarossian