Abstract: A method of assembling a protein nanostructure on a surface including selectively patterning a surface with a fixation site, bringing a protein node into contact with the surface, and allowing the protein node to bond with the fixation site, so that the position and/or orientation of the protein node is constrained, and compositions.
Abstract: Engineered proteins are used in the assembly of two-dimensional and three-dimensional nanostructure assemblies, based on systematic design and production of protein node structures that can be interconnected, for example, with streptavidin or streptavidin-incorporating struts to produce structures with defined dimensions and geometry. Nanostructure assemblies having utility as functional devices or as resists for the patterning of substrates have architectures including polygons, polyhedra, two-dimensional lattices, and three-dimensional lattices.
Type:
Grant
Filed:
September 28, 2010
Date of Patent:
August 11, 2015
Assignee:
IMIPLEX LLC
Inventors:
F. Raymond Salemme, Patricia C. Weber, Mark A. Rould
Abstract: A streptavidin macromolecular adaptor (SAMA) protein may be used for the controlled assembly of nanostructure building blocks and struts including streptavidin:SAMA complexes.
Type:
Grant
Filed:
April 23, 2010
Date of Patent:
March 31, 2015
Assignee:
Imiplex LLC
Inventors:
Francis Raymond Salemme, Patricia C. Weber
Abstract: Engineered proteins are used in the assembly of two-dimensional and three-dimensional nanostructure assemblies, based on systematic design and production of protein node structures that can be interconnected, for example, with streptavidin or streptavidin-incorporating struts to produce structures with defined dimensions and geometry. Nanostructure assemblies having utility as functional devices or as resists for the patterning of substrates have architectures including polygons, polyhedra, two-dimensional lattices, and three-dimensional lattices.
Type:
Application
Filed:
September 28, 2010
Publication date:
April 14, 2011
Applicant:
IMIPLEX LLC
Inventors:
F. Raymond Salemme, Patricia C. Weber, Mark A. Rould
Abstract: A streptavidin macromolecular adaptor (SAMA) protein may be used for the controlled assembly of nanostructure building blocks and struts including streptavidin:SAMA complexes.
Type:
Application
Filed:
April 23, 2010
Publication date:
December 30, 2010
Applicant:
IMIPLEX LLC
Inventors:
Franois Raymond Salemme, Patricia C. Weber