Patents Assigned to Immerge Biotherapeutics, Inc.
  • Method to enrich for ?(1,3)-galactosyltransferase null pig cells
    Patent number: 7547522
    Abstract: The invention relates to the genetic manipulation of non-human animals. More particularly, the invention relates to genetic manipulation of non-human animals to be used for xenotransplantation. The invention provides a method of selecting GGTA 1 null cells, a viable GGTA 1 null swine, methods for making such swine, and methods of using cells, tissues and organs of such swine for xenotransplantation.
    Type: Grant
    Filed: August 13, 2003
    Date of Patent: June 16, 2009
    Assignee: Immerge Biotherapeutics, Inc.
    Inventor: Robert J. Hawley
  • ?(1,3)-galactosyltransferase knockout swine, tissues and organs
    Patent number: 7547816
    Abstract: The invention relates to the genetic manipulation of non-human animals. More particularly, the invention relates to genetic manipulation of non-human animals to be used for xenotransplantation. The invention provides viable gene knockout swine including swine in which the ?(1,3)-galactosyltransferase gene has been disrupted, methods for making such swine, and methods of using the tissues and organs of such swine for xenotransplantation.
    Type: Grant
    Filed: December 23, 2002
    Date of Patent: June 16, 2009
    Assignees: The Curators of the University of Missouri, Immerge Biotherapeutics, Inc.
    Inventors: Billy N. Day, Robert J. Hawley, Randall S. Prather
  • Gamma herpesvirus DNA and methods of use
    Patent number: 6942863
    Abstract: Isolated polynucleotides and polypeptides derived from the genome of swine gamma-herpesviruses are disclosed, including recombinant cells and vectors encoding such polypeptides and expressing such polynucleotides. Use of the novel polynucleotides as probes of the swine genome is also described. Assay methods employing antibodies against the isolated polypeptides are also disclosed.
    Type: Grant
    Filed: January 23, 2002
    Date of Patent: September 13, 2005
    Assignee: Immerge Biotherapeutics, Inc.
    Inventor: Clive Patience