Patents Assigned to ImmPACT-Bio Ltd.
  • Universal platform for preparing an inhibitory chimeric antigen receptor (iCAR)
    Patent number: 11660315
    Abstract: The present invention provides a method of identifying a target for preparing an inhibitory chimeric antigen receptor (iCAR) or a protective chimeric antigen receptor (pCAR) capable of preventing or attenuating undesired activation of an effector immune cell. Also provided are a list of iCAR targets, as well as vectors and transduced effector immune cells comprising the nucleic acid molecule and methods for treatment of cancer comprising administering the transduced effector immune cells are further provided.
    Type: Grant
    Filed: September 28, 2018
    Date of Patent: May 30, 2023
    Assignees: ImmPACT-Bio Ltd., Gavish-Galilee Bio Applications Ltd.
    Inventors: Gideon Gross, Will Gibson, Dvir Dahary, Merav Beiman