Abstract: Contemplated compositions, devices, and methods are drawn to various antigens from the pathogen M. tuberculosis and their use in vaccines, therapeutic agents, and various diagnostic tests. In particularly preferred aspects, the antigens are immunodominant and have quantified and known relative reactivities with respect to sera of a population infected with the pathogen, and/or have a known association with a disease parameter.
Type:
Grant
Filed:
February 14, 2012
Date of Patent:
December 11, 2012
Assignee:
ImmportTherapeutics, Inc.
Inventors:
Philip Felgner, Xiaowu Liang, Maria Laura Gennaro