Abstract: The present invention relates to the treatment of B-cell mediated immune disorders such as rheumatoid arthritis, systemic lupus erythromatomus, diabetes mellitus, and multiple sclerosis. In particular, the present invention relates to the treatment of B-cell mediated immune disorders using antibodies which bind to membrane-bound free light chain expressed on the surface of plasma cell precursors.
Type:
Application
Filed:
April 7, 2010
Publication date:
May 10, 2012
Applicant:
IMMUNE SYSTEM THERAPEUTICS LTD
Inventors:
Andrew T. Hutchinson, Darren R. Jones, Robert L. Raison, Parisa Asvadi, Rosanne D. Dunn
Abstract: The present invention relates to methods for the treatment of multiple myeloma. More particularly, the present invention relates to a method for inducing apoptosis in myeloma cells by administration of a K121-like antibody.
Type:
Grant
Filed:
January 18, 2008
Date of Patent:
November 23, 2010
Assignee:
Immune System Therapeutics Ltd
Inventors:
Robert Lindsay Raison, Rosanne Dorothy Dunn, Boon Hwa Andre Choo
Abstract: The present invention relates to methods for the treatment of multiple myeloma. More particularly, the present invention relates to a method for inducing apoptosis in myeloma cells by administration of a K121-like antibody.
Type:
Grant
Filed:
January 18, 2008
Date of Patent:
July 7, 2009
Assignee:
Immune System Therapeutics Ltd
Inventors:
Robert Lindsay Raison, Rosanne Dorothy Dunn, Boon Hwa Andre Choo
Abstract: The present invention relates to methods for the treatment of multiple myeloma. More particularly, the present invention relates to a method for inducing apoptosis in myeloma cells by administration of a K121-like antibody.
Type:
Grant
Filed:
July 5, 2002
Date of Patent:
March 18, 2008
Assignee:
Immune System Therapeutics Ltd
Inventors:
Robert Lindsay Raison, Rosanne Dorothy Dunn, Boon Hwa Andre Choo