Abstract: The invention relates to a colorimetric method for detecting bacterial or fungal pathogens by detecting peptidoglycan or (1-3)-?-D-glucan in a sample.
Type:
Grant
Filed:
January 26, 2018
Date of Patent:
February 25, 2020
Assignee:
Immunetics, Inc.
Inventors:
Neil X. Krueger, Andrew Han, Andrew E. Levin, Victor Kovalenko
Abstract: The invention relates to a colorimetric method for detecting bacterial or fungal pathogens by detecting peptidoglycan or (1-3)-?-D-glucan in a sample.
Type:
Application
Filed:
December 4, 2013
Publication date:
November 6, 2014
Applicant:
Immunetics, Inc.
Inventors:
Andrew Bodkin, Mark Villafuerte, Hendrick Melo, Neil X. Krueger, Andrew Han, Andrew E. Levin
Abstract: The invention relates to a colorimetric method for detecting bacterial or fungal pathogens by detecting peptidoglycan or (1-3)-?-D-glucan in a sample.
Type:
Grant
Filed:
May 21, 2013
Date of Patent:
September 23, 2014
Assignee:
Immunetics, Inc.
Inventors:
Andrew Han, Andrew E. Levin, Neil X. Krueger, Victor Kovalenko
Abstract: The invention relates to a colorimetric method for detecting bacterial or fungal pathogens by detecting peptidoglycan or (1-3)-?-D-glucan in a sample.
Type:
Application
Filed:
May 21, 2013
Publication date:
January 9, 2014
Applicant:
Immunetics, Inc.
Inventors:
Andrew Han, Andrew E. Levin, Neil X. Krueger, Victor Kovalenko
Abstract: The invention relates to a colorimetric method for detecting bacterial or fungal pathogens by detecting peptidoglycan or (1-3)-?-D-glucan in a sample.
Abstract: The invention relates to a colorimetric method for detecting bacterial or fungal pathogens by detecting peptidoglycan or (1-3)-?-D-glucan in a sample.
Abstract: The invention relates to a colorimetric method for detecting bacterial or fungal pathogens by detecting peptidoglycan or (1-3)-?-D-glucan in a sample.
Type:
Grant
Filed:
April 28, 2006
Date of Patent:
October 6, 2009
Assignee:
Immunetics, Inc.
Inventors:
Victor Kovalenko, Andrew E. Levin, Lee Anne Beausang
Abstract: The invention provides a heterogeneous immunoassay for detection of antibodies and antigens based on specific antigen-antibody immune complex formation with multiple antigen-bearing conjugate components. The invention further provides means for optimizing the assay format for the detection of both low and high-affinity antibodies, and provides means for quantitative detection of both antibody and the corresponding antigen present in a sample. In preferred embodiments, the invention can be practiced to detect presence in biological fluid samples of antibodies to Bacillus anthracis related antigens.
Abstract: The invention provides a heterogeneous immunoassay for detection of antibodies and antigens based on specific antigen-antibody immune complex formation with multiple antigen-bearing conjugate components. The invention further provides means for optimizing the assay format for the detection of both low and high-affinity antibodies, and provides means for quantitative detection of both antibody and the corresponding antigen present in a sample. In preferred embodiments, the invention can be practiced to detect presence in biological fluid samples of antibodies to Bacillus anthracis related antigens.
Abstract: The invention provides a heterogeneous immunoassay for detection of antibodies and antigens based on specific antigen-antibody immune complex formation with multiple antigen-bearing conjugate components. The invention further provides means for optimizing the assay format for the detection of both low and high-affinity antibodies, and provides means for quantitative detection of both antibody and the corresponding antigen present in a sample.
Abstract: The invention relates to a colorimetric method for detecting bacterial or fungal pathogens by detecting peptidoglycan or (1-3)-?-D-glucan in a sample.
Type:
Application
Filed:
April 28, 2006
Publication date:
November 30, 2006
Applicant:
Immunetics, Inc.
Inventors:
Victor Kovalenko, Andrew Levin, Lee Anne Beausang
Abstract: The invention provides a heterogeneous immunoassay for detection of antibodies and antigens based on specific antigen-antibody immune complex formation with multiple antigen-bearing conjugate components. The invention further provides means for optimizing the assay format for the detection of both low and high-affinity antibodies, and provides means for quantitative detection of both antibody and the corresponding antigen present in a sample.
Abstract: The invention provides a heterogeneous immunoassay for detection of antibodies and antigens based on specific antigen-antibody immune complex formation with multiple antigen-bearing conjugate components. The invention further provides means for optimizing the assay format for the detection of both low and high-affinity antibodies, and provides means for quantitative detection of both antibody and the corresponding antigen present in a sample.
Abstract: Systems and methods for processing membrane flow-through assays to provide more rapid testing. The systems include a plate for receiving a cartridge having a membrane which, for example, can be a membrane with antigens or antibodies fixed thereon. The agents can be pipetted onto the membrane and the systems can be activated to agitate the cartridge to evenly distribute the agents over the membrane, and a vacuum source can apply negative pressure to one side of the membrane to draw the agent therethrough.