Patents Assigned to Immunex
  • Method for producing T.sub.H -independent cytotoxic T lymphocytes
    Patent number: 5470730
    Abstract: The present invention relates to cytotoxic T lymphocytes (CTLs) which have been converted to a helper T cell independent phenotype by introducing a recombinant expression vector encoding IL-1 receptor into the CTL. The resulting CTLs have the ability to grow or function independent of T cell help.
    Type: Grant
    Filed: August 8, 1994
    Date of Patent: November 28, 1995
    Assignees: Immunex, Fred Hutchinson Cancer Research Center
    Inventors: Phillip D. Greenberg, Robert W. Overell