Abstract: The invention is a composition and method for non-specific enhancement of immune responses in human and animal recipients. A colostrum-derived feed additive (CDFA) for human or veterinary use comprises a sprayed-dried preparation of pasteurized and homogenized first milking colostrum that enhances immune responses in a recipient receiving an oral administration. Generally, CDFA is administered in a conditioning dose once per day during a conditioning period of time from about 7 to 14 days, and then in a maintenance dose administered once per day during a period that follows the conditioning period. The maintenance dose is about one-half the concentration of the conditioning dose. Administration of CFDA enhances immune response in a recipient in a dose-dependent manner.

Abstract: A product and method of treating failure of passive immunity transfer and for stimulating growth and milk production in cows by administration of proteins purified from bovine colostrum is disclosed. Injecting, either subcutaneously or intravenously, prepared bovine colostrum containing immunoglobulins and nonspecific proteins increases immunoglobulins in the blood stream to effect passive transfer after gut closure. Also administration in spray dried form as a diet supplement to growing calves or adult cows improves growth and milk production due to the presence of previously unappreciated nonspecific proteins.