Abstract: Tripeptides capable of regulating the function of cells of the mammalian immune and/or central nervous system, pharmaceutical compositions containing the peptides and methods of use thereof are provided.
Type:
Grant
Filed:
August 26, 1993
Date of Patent:
June 17, 1997
Assignee:
Immunobiology Research Institute, Inc.
Inventors:
Gideon Goldstein, Ponniah Shenbagamurthi, James I. Koenig
Abstract: The present invention provides novel nucleotide and amino acid sequences for human thymopoietin .alpha., .beta., and .gamma., methods of recombinantly expressing same, and diagnostic and therapeutic uses thereof.
Type:
Grant
Filed:
December 21, 1993
Date of Patent:
December 5, 1995
Assignee:
Immunobiology Research Institute, Inc.
Inventors:
Crafford A. Harris, Gideon Goldstein, John J. Siekierka, Mary A. Talle, Ponniah Shenbagamurthi, Michael D. Culler, Diane R. Setcavage
Abstract: Tetrapeptides and pentapeptides are disclosed which are capable of regulating the function of cells of the mammalian immune system. Also provided are pharmaceutical compositions containing the peptides and methods of use thereof.
Type:
Grant
Filed:
January 9, 1990
Date of Patent:
March 29, 1994
Assignee:
Immunobiology Research Institute, Inc.
Inventors:
George Heavner, Gideon Goldstein, Tapan Audhya
Abstract: Pentapeptides are disclosed which are capable of regulating the function of cells of the mammalian immune and/or nervous system. Also provided are pharmaceutical compositions containing the peptides and methods of use thereof.
Type:
Grant
Filed:
June 3, 1991
Date of Patent:
June 1, 1993
Assignee:
Immunobiology Research Institute, Inc.
Inventors:
Gideon Goldstein, Tapan Audhya, George Heavner, Mohmed K. Anwer
Abstract: A composition for use in the topical treatment of skin disorders such as dermatitis or poison ivy, which comprises an effective amount of thymopentin and a suitable carrier is provided. A method for treating skin disorders and a method for making a topical composition are disclosed.
Abstract: A multi-functional mammalian peptide probursin isolated in purified form, produced synthetically or recombinantly can be used therapeutically for treatment of immune disorders and tumor inhibition.
Type:
Grant
Filed:
December 20, 1988
Date of Patent:
February 19, 1991
Assignee:
Immunobiology Research Institute, Inc.
Inventors:
Tapan Audhya, Gideon Goldstein, George Heavner