Abstract: The invention relates to pyridine-3,5-bis-thiocyanates which are new active substances for the treatment and prevention of retroviral infections and secondary diseases thereof, in particular HIV infections and AIDS, from the group of deubiquitinase inhibitors. Administration of the compounds of the invention increases the immunogenicity of viral proteins and thus the antiviral response.
Type:
Grant
Filed:
July 10, 2015
Date of Patent:
March 17, 2020
Assignee:
IMMUNOLOGIK GMBH
Inventors:
Ulrich Schubert, Christian Setz, Wolfgang Brysch, Jörg Von Wegerer
Abstract: The invention relates to pyridine-3,5-bis-thiocyanates which are new active substances for the treatment and prevention of retroviral infections and secondary diseases thereof, in particular HIV infections and AIDS, from the group of deubiquitinase inhibitors. Administration of the compounds of the invention increases the immunogenicity of viral proteins and thus the antiviral response.
Type:
Application
Filed:
July 10, 2015
Publication date:
July 20, 2017
Applicant:
IMMUNOLOGIK GMBH
Inventors:
Ulrich Schubert, Christian Setz, Wolfgang Brysch, Jörg Von Wegerer