Patents Assigned to Immunopharmaceutic Institute of Hefei Ruida Co., Ltd.
  • Antibody or antibody fragment capable of binding to lung-specific X protein and use thereof
    Patent number: 10919978
    Abstract: The present application provides an antibody or antibody fragment capable of binding to a lung-specific X protein and being used to treat a tumor, and a use thereof. The antibody or antibody fragment includes heavy chain CDRs having amino acid sequences of SEQ ID NO: 1, SEQ ID NO: 2, and SEQ ID NO: 3 and light chain CDRs having amino acid sequences of SEQ ID NO: 4, SEQ ID NO: 5, and SEQ ID NO: 6. Alternatively, the antibody or antibody fragment includes heavy chain CDRs having amino acid sequences of SEQ ID NO: 1, SEQ ID NO: 7, and SEQ ID NO: 3 and light chain CDRs having amino acid sequences of SEQ ID NO: 8, SEQ ID NO: 5, and SEQ ID NO: 6. The antibody is a chimeric antibody.
    Type: Grant
    Filed: May 25, 2017
    Date of Patent: February 16, 2021
    Assignee: IMMUNOPHARMACEUTIC INSTITUTE OF HEFEI RUIDA CO., LTD.
    Inventors: Zhigang Tian, Haiming Wei, Xiaohu Zheng, Rui Sun, Weihua Xiao, Dan Liu, Baoru Wang
  • ANTIBODY OR ANTIBODY FRAGMENT CAPABLE OF BINDING TO LUNG-SPECIFIC X PROTEIN AND USE THEREOF
    Publication number: 20190322758
    Abstract: The present application provides an antibody or antibody fragment capable of binding to a lung-specific X protein and being used to treat a tumor, and a use thereof. The antibody or antibody fragment includes heavy chain CDRs having amino acid sequences of SEQ ID NO: 1, SEQ ID NO: 2, and SEQ ID NO: 3 and light chain CDRs having amino acid sequences of SEQ ID NO: 4, SEQ ID NO: 5, and SEQ ID NO: 6. Alternatively, the antibody or antibody fragment includes heavy chain CDRs having amino acid sequences of SEQ ID NO: 1, SEQ ID NO: 7, and SEQ ID NO: 3 and light chain CDRs having amino acid sequences of SEQ ID NO: 8, SEQ ID NO: 5, and SEQ ID NO: 6. The antibody is a chimeric antibody.
    Type: Application
    Filed: May 25, 2017
    Publication date: October 24, 2019
    Applicant: Immunopharmaceutic Institute of Hefei Ruida Co., Ltd.
    Inventors: Zhigang Tian, Haiming Wei, Xiaohu Zheng, Rui Sun, Weihua Xiao, Dan Liu, Baoru Wang