Patents Assigned to Immunotech S.A.
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Patent number: 7678583Abstract: A multifunctional reagent for erythrocytes containing an amount sufficient to produce the lysis of erythrocytes or the sphering of erythrocytes in such a way that they can be detected by a cytometer or an automatic counting device, of a carbamate or of an agent inducing the formation by the erythrocytes, from carbonate and from a nitrogenated heterocycle or ammonium ions, of a carbamate combined with the absorption of CO2 by the erythrocytes, process for lysing or sphering erythrocytes and preparation process for leucocytes.Type: GrantFiled: October 8, 2007Date of Patent: March 16, 2010Assignee: Immunotech, S.A.Inventors: Andre van Agthoven, Jean-Pierre Daziano, John Allen Maples
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Publication number: 20090060937Abstract: Oligonucleotides containing the non-palindromic sequence motif: X1X2X3X4X5X6X7X8, wherein X1 is C, T, G or A (preferably T or C); wherein X2 is C, T, G or A; wherein X7 is C, T, G or A (preferably G); at least three, and preferably all, of X3, X4, X5, X6 and X8 are T; and with the proviso that, in the motif, a C does not precede a G (in other terms, the nucleic acid motif does not consist of a CpG oligonucleotide), that modulate the immune response of animals of the order Primate, including humans, are disclosed. This immune modulation is characterized by stimulation of proliferation, differentiation, cytokine production and antibody production on B-cells and cell differentiation on plasmacytoid dendritic cells.Type: ApplicationFiled: April 28, 2008Publication date: March 5, 2009Applicant: IMMUNOTECH S.A.Inventor: Ricardo Agustin Lopez
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Patent number: 7381807Abstract: Oligonucleotides containing the non-palindromic sequence motif: X1X2X3X4X5X6X7X8, wherein X1 is C,T,G or A (preferably T or C); wherein X2 is C,T,G or A; wherein X7 is C,T,G or A (preferably G); at least three, and preferably all, of X3, X4, X5, X6 and X8 are T; and with the proviso that, in the motif, a C does not precede a G (in other terms, the nucleic acid motif does not consist of a CpG oligonucleotide), that modulate the immune response of animals of the order Primate, including humans, are disclosed. This immune modulation is characterized by stimulation of proliferation, differentiation, cytokine production and antibody production on B-cells and cell differentiation on plasmacytoid dendritic cells.Type: GrantFiled: July 8, 2005Date of Patent: June 3, 2008Assignee: Immunotech S.A.Inventor: Ricardo Agustin Lopez
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Patent number: 7300797Abstract: A multifunctional reagent for erythrocytes containing an amount sufficient to produce the lysis of erythrocytes or the sphering of erythrocytes in such a way that they can be detected by a cytometer or an automatic counting device, of a carbamate or of an agent inducing the formation by the erythrocytes, from carbonate and from a nitrogenated heterocycle or ammonium ions, of a carbamate combined with the absorption of CO2 by said erythrocytes, process for lysing or sphering erythrocytes and preparation process for leucocytes.Type: GrantFiled: September 14, 2001Date of Patent: November 27, 2007Assignee: Immunotech, S.A.Inventors: Andre van Agthoven, Jean-Pierre Daziano, John Allen Maples
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Patent number: 7038029Abstract: Oligonucleotides containing the non-palindromic sequence motif: X1X2X3X4X5X6X7X8, wherein X1 is C,T,G or A (preferably T or C); wherein X2 is C,T,G or A; wherein X7 is C,T,G or A (preferably G); at least three, and preferably all, of X3, X4, X5, X6 and X8 are T; and with the proviso that, in the motif, a C does not precede a G (in other terms, the nucleic acid motif does not consist of a CpG oligonucleotide), that modulate the immune response of animals of the order Primate, including humans, are disclosed. This immune modulation is characterized by stimulation of proliferation, differentiation, cytokine production and antibody production on B-cells and cell differentiation on plasmacytoid dendritic cells.Type: GrantFiled: December 4, 2002Date of Patent: May 2, 2006Assignee: Immunotech S.A.Inventor: Ricardo Agustin Lopez
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Publication number: 20050276789Abstract: Oligonucleotides containing the non-palindromic sequence motif: X1X2X3X4X5X6X7X8, wherein X1 is C,T,G or A (preferably T or C); wherein X2 is C,T,G or A; wherein X7 is C,T,G or A (preferably G); at least three, and preferably all, of X3, X4, X5, X6 and X8 are T; and with the proviso that, in the motif, a C does not precede a G (in other terms, the nucleic acid motif does not consist of a CpG oligonucleotide), that modulate the immune response of animals of the order Primate, including humans, are disclosed. This immune modulation is characterized by stimulation of proliferation, differentiation, cytokine production and antibody production on B-cells and cell differentiation on plasmacytoid dendritic cells.Type: ApplicationFiled: July 8, 2005Publication date: December 15, 2005Applicant: IMMUNOTECH S.A.Inventor: Ricardo Lopez
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Publication number: 20040006032Abstract: Oligonucleotides containing the non-palindromic sequence motif:Type: ApplicationFiled: December 4, 2002Publication date: January 8, 2004Applicant: Immunotech S.A.Inventor: Ricardo Agustin Lopez