Abstract: Cytotoxic anti-LAG-3 monoclonal antibodies or fragments thereof causing depletion of LAG-3+ activated T cells are described, as are related pharmaceuticals and methods of treating. Also described are related nucleic acid and protein sequences.
Type:
Application
Filed:
June 25, 2010
Publication date:
March 24, 2011
Applicants:
IMMUTEP PARC CLUB ORSAY, INSERM - INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE
Inventors:
FREDERIC TRIEBEL, BERNARD VANHOVE, THOMAS HAUDEBOURG