Patents Assigned to IMMVIRA CO., LIMITED
  • Construction of oncolytic herpes simplex viruses (oHSV) obligate vector and constructs for cancer therapy
    Patent number: 11439679
    Abstract: An obligate oHSV vector comprising modified viral DNA genome is provided. A recombinant oHSV-1 construct comprising the obligate oHSV vector and a heterologous nucleic acid sequence encoding an immunostimulatory and/or immunotherapeutic agent is also provided. Compositions comprising the recombinant oHSV-1 construct can be used for treating cancers.
    Type: Grant
    Filed: September 14, 2020
    Date of Patent: September 13, 2022
    Assignee: IMMVIRA CO., LIMITED
    Inventors: Grace Guoying Zhou, Xiaoqing Chen, Xianjie Liu
  • Construction of oncolytic herpes simplex viruses (oHSV) obligate vector and constructs for cancer therapy
    Patent number: 10821140
    Abstract: An obligate oHSV vector comprising modified viral DNA genome is provided. A recombinant oHSV-1 construct comprising the obligate oHSV vector and a heterologous nucleic acid sequence encoding an immunostimulatory and/or immunotherapeutic agent is also provided. Compositions comprising the recombinant oHSV-1 construct can be used for treating cancers.
    Type: Grant
    Filed: April 22, 2016
    Date of Patent: November 3, 2020
    Assignee: IMMVIRA CO., LIMITED
    Inventors: Grace Guoying Zhou, Xiaoqing Chen, Xianjie Liu