Abstract: The invention provides a controlled release oral solid formulation comprising (a) a controlled release component comprising core comprising levodopa and/or an ester of levodopa or salts thereof, wherein the core is coated with a layer of a muco-adhesive polymer and externally coated with a layer of an enteric coated polymer; and (b) a decarboxylase inhibitor component.
Type:
Grant
Filed:
October 7, 2014
Date of Patent:
October 16, 2018
Assignee:
IMPAX LABORATORIES, LLC
Inventors:
Ann Hsu, Liang C. Dong, Amy Ding, Suneel Gupta