Patents Assigned to Imutran Limited
  • Down-regulation resistant C3 convertase
    Patent number: 7002001
    Abstract: Native complement pathway proteins modified such that the protein is capable of forming a down-regulation resistant C3 convertase. Preferably the modified protein is a modified human C3 protein. DNA sequences encoding such proteins are also provided, together with DNA constructs. Conjugates comprising such proteins and a specific binding moiety, for example an antibody, are also described, as are uses of such proteins and/or conjugates in therapy.
    Type: Grant
    Filed: June 6, 2001
    Date of Patent: February 21, 2006
    Assignee: Imutran Limited
    Inventors: Timothy Charles Farries, Richard Alexander Harrison
  • Down-regulation resistant C3 convertase
    Patent number: 6268485
    Abstract: Native complement pathway proteins modified such that the protein is capable of forming a down-regulation resistant C3 convertase. Preferably the modified protein is a modified human C3 protein. DNA sequences encoding such proteins are also provided, together with DNA constructs. Conjugates comprising such proteins and a specific binding moiety, for example an antibody, are also described, as are uses of such proteins and/or conjugates in therapy.
    Type: Grant
    Filed: April 15, 1999
    Date of Patent: July 31, 2001
    Assignee: Imutran Limited
    Inventors: Timothy Charles Farries, Richard Alexander Harrison
  • Modified human C3 DNA sequences and vectors
    Patent number: 6221657
    Abstract: This invention is directed to DNA sequences encoding narrative complement pathway proteins modified such that the protein is capable of forming a stable C3 convertase. The modified C3 proteins are useful in therapy.
    Type: Grant
    Filed: August 11, 1998
    Date of Patent: April 24, 2001
    Assignee: Imutran Limited
    Inventors: Richard Alexander Harrison, Timothy Charles Farries
  • Modified human C3 proteins
    Patent number: 5849297
    Abstract: Narrative complement pathway proteins modified such that the protein is capable of forming a stable C3 convertase. Preferably the modified protein is a modified human C3 protein. DNA sequences encoding such proteins are also provided, together with DNA constructs. Conjugates comprising such proteins and a specific binding moiety, for example an antibody, are also described, as are uses of such proteins and/or conjugates in therapy.
    Type: Grant
    Filed: February 7, 1997
    Date of Patent: December 15, 1998
    Assignee: Imutran Limited
    Inventors: Richard Alexander Harrison, Timothy Charles Farries