Patents Assigned to Imvax, Inc.
  • Publication number: 20200054761
    Abstract: The present disclosure provides methods and compositions for enhancing the treatment of a cancer, particularly in a human subject, by administering antibody drug conjugates (ADCs) to inhibit or kill specific myeloid/monocyte/macrophage-lineage cells. The myeloid/monocyte/macrophage-lineage cells are identified, for example, by expression of one or more of the scavenger receptors CD204 and CD163, and/or mannose receptor-1 (CD206).
    Type: Application
    Filed: February 22, 2018
    Publication date: February 20, 2020
    Applicants: Thomas Jefferson University, Imvax, Inc.
    Inventors: David W. Andrews, Douglas C. Hooper, Arthur Howe