Abstract: Compounds and compositions including stereoisomers of 6-phenylhexanamide derivative small molecule mitofusin activators are described. In particular, mitofusin activators comprising derivatives of (trans-4-hydroxycyclohexyl)-6-phenylhexanamide, which are useful for treating diseases or disorders associated with a mitochondria-associated disease, disorder, or condition such as diseases or disorders associated with mitofusin-1 (MFN1) and/or mitofusin-2 (MFN2), or mitochondrial dysfunction, are described. Methods of treatment and pharmaceutical formulations are also described.

Abstract: A method for generating hydrogen from a mixture of nitrogen containing borane compound and active metal borohydride reactants uses a catalyst-free water vapor driven hydrothermolysis process. The method involves mechanically mixing a selected ratio of nitrogen containing borane compound such as ammonia borane and an active metal borohydride such as sodium borohydride to produce a mixture, combining the mixture with a water vapor source, and heating the mixture and water vapor source to a temperature within a near ambient temperature range of 30° C. to 104° C., until a product gas comprising hydrogen is released. The heating can be at a constant temperature or at increasing temperatures. Water vapor and impurities are removed from the product gas to produce purified hydrogen gas.

Abstract: The hydrogen storage product comprises one or more reduced-graphene oxide layers functionalized with a boron species and decorated with an alkali or alkaline earth metal. Each layer of the structure further comprises boron-oxygen functional groups comprising oxygen atoms bonded to boron atoms. The hydrogen storage product has a composition suitable for physisorption of hydrogen molecule, and operates to reversibly store hydrogen under operating conditions of low pressure and ambient temperature.

Abstract: A fruit snack with probiotics that is stable at room temperature is manufactured by combining various ingredients including fruit juices/purees to produce a slurry and cooking the slurry to produce a center that contains a high moisture content. The fruit snack center is covered with a barrier layer which in turn is covered by an outer layer that contains heat sensitive ingredients, such as probiotic cultures. The barrier layer substantially prevents migration of moisture from the center to the outer layer, and the fruit snack is cooled prior to applying the outer layer to minimize damage/harm to the heat sensitive ingredients. In addition to including probiotic cultures and being stable at room temperature, the fruit snack has other desirable characteristics including a chewy soft texture and fruit-flavorings, and may be manufactured using traditional processes.

Abstract: A method for generating hydrogen from a mixture of nitrogen containing borane compound and active metal borohydride reactants uses a catalyst-free water vapor driven hydrothermolysis process. The method involves mechanically mixing a selected ratio of nitrogen containing borane compound such as ammonia borane and an active metal borohydride such as sodium borohydride to produce a mixture, combining the mixture with a water vapor source, and heating the mixture and water vapor source to a temperature within a near ambient temperature range of 30° C. to 104° C., until a product gas comprising hydrogen is released. The heating can be at a constant temperature or at increasing temperatures. Water vapor and impurities are removed from the product gas to produce purified hydrogen gas.

Abstract: The preferred embodiments of the present invention are directed to methods and systems for dynamic route estimation and prediction using discrete sampled location updates from various mobile devices for the purpose of providing a graphical representation of a mobile device's route along a known network path of map data. The embodiments also provide supplemental route metrics, such as traveled distance, elapsed time, etc., and the capability to assign destination points for the purpose of providing the ability to modify location update points in an application, such as a route planner, and/or to store the dynamically generated route based on various preferences for later retrieval.

Abstract: The present invention is directed to a system and method for collecting and maintaining an up-to-date database of points of interests, whereby agents of the points of interests, such as owners or operators of hotels or restaurants, can register their point of interest onto the database by uploading their contact information and physical address. Subsequently, on a periodic basis, the agents of the points of interests may log into the system and update their information, such as operating hours. The collected data is then made accessible to the general public and can be searched through using a variety of search criteria.

Abstract: The present invention is directed to a system and method for collecting and maintaining an up-to-date database of points of interests, whereby agents of the points of interests, such as owners or operators of hotels or restaurants, can register their point of interest onto the database by uploading their contact information and physical address. Subsequently, on a periodic basis, the agents of the points of interests may log into the system and update their information, such as operating hours. The collected data is then made accessible to the general public and can be searched through using a variety of search criteria.

Abstract: A user interface is presented through which a training plan is established. The training plan includes a plurality of workouts each describing a human physical activity. The training plan is stored within data storage for selection by any of a plurality of users. In response to a user among said plurality of users selecting said training plan, data describing at least one workout in said training plan is electronically transmitted to a client device associated with the user.

Abstract: The present invention is directed to a system and method for providing real-time position information of one party to another party by utilizing a conventional telecommunication network system such as the convention telephone network, a mobile telecommunications network, a computer network, or the Internet. More specifically, the preferred embodiments of the present invention allow a caller and a receiver of a telephone call to provide to and receive from each other position information related to the caller and/or receiver's physical location, including address information, GPS coordinates, nearby fixed locations such as a parking structure, etc. Additionally, the preferred embodiments of the present invention allow a caller and receiver to retrieve routing instructions or maps for traveling to or from each other.

Abstract: The present invention is directed to a system and method for providing real-time position information of one party to another party by utilizing a conventional telecommunication network system such as the convention telephone network, a mobile telecommunications network, a computer network, or the Internet. More specifically, the preferred embodiments of the present invention allow a caller and a receiver of a telephone call to provide to and receive from each other position information related to the caller and/or receiver's physical location, including address information, GPS coordinates, nearby fixed locations such as a parking structure, etc. Additionally, the preferred embodiments of the present invention allow a caller and receiver to retrieve routing instructions or maps for traveling to or from each other.

Abstract: A communication system (410) wherewith sources (414) and targets (416) employ a key server (420) to exchange transactions (424). A first request to the key server includes a source assertion (422) from an authentication authority (418), and optionally a key (430). The key server provides a transaction ID (428), and the key if not already provided, in reply to this request. The key server stores the transaction ID and source assertion. The source encrypts the transaction and sends it with the transaction ID to the targets. A second request to the key server includes a target assertion and the transaction ID. The key server provides the key in reply to this request. The key server also stores the target assertion in association with the transaction ID. The respective assertions then establish the source and targets of the transaction in a manner that cannot plausibly be repudiated.

Abstract: The present invention is directed to a system and method for searching and retrieving location information associated with one or more points of interests, whereby the search criteria can be dependent upon the location of a point of interest with respect to the real-time position of the user, and any preferences or search restrictions selected by the user, such as rating information about the point of interest. Upon selecting a point of interest from the search result, the user is then given further information regarding the selected point of interest, including but not limited to directions for traveling to the point of interest. Additionally, the present invention can provide to the user a proximity notification once the user is within a certain distance from the point interest.

Abstract: The present invention is directed to a method and apparatus for storing, referencing, retrieving, and graphically displaying spatial and non-spatial related information of a mobile computing device, such as a laptop computer or a cellular telephone. The spatial-related information may be obtained by using positioning tracking systems such as a global positioning system, whereas the non-spatial related information may include communication activities associated with the mobile computing device, such as phone calls, e-mails, text messages, pages, etc. The present invention also provides methods and apparatus of sharing event information between mobile communication devices as well as related navigational information for traveling to an event from a real-time position of a mobile communication device.

Abstract: The present invention is directed to a system and method for providing real-time position information of one party to another party by utilizing a conventional telecommunication network system such as the convention telephone network, a mobile telecommunications network, a computer network, or the Internet. More specifically, the preferred embodiments of the present invention allow a caller and a receiver of a telephone call to provide to and receive from each other position information related to the caller and/or receiver's physical location, including address information, GPS coordinates, nearby fixed locations such as a parking structure, etc. Additionally, the preferred embodiments of the present invention allow a caller and receiver to retrieve routing instructions or maps for traveling to or from each other.

Abstract: The present invention is directed to a method and apparatus for sending and retrieving location relevant information to a user by selecting and designating a point of interest that is displayed on a graphical user interface and sending the location information associated with that point of interest to a receiver that is also selected using the graphical user interface. The location relevant information may also include mapped routes, waypoints, geo-fenced areas, moving vehicles etc. Updated location relevant information may also be continuously sent to the user while generating updated mapping information on the graphical user interface. The present invention may be practiced by using communication devices such as a personal computer, a personal digital assistance, in-vehicle navigation systems, or a mobile telephone.

Abstract: A security server system and method permitting participants acting as the source or destinations for a message or a conversation with multiple messages to securely communicate the messages. The messages have a message header and a message content. A message router connects the participants via a network and delivers the message between the participants based on the message header. A key server creates, stores, and releases conversation keys that the participants use to protect the message content of the message.

Abstract: The present invention is directed to a system and method for searching and retrieving location information associated with one or more points of interests, whereby the search criteria can be dependent upon the location of a point of interest with respect to the real-time position of the user, and any preferences or search restrictions selected by the user, such as rating information about the point of interest. Upon selecting a point of interest from the search result, the user is then given further information regarding the selected point of interest, including but not limited to directions for traveling to the point of interest. Additionally, the present invention can provide to the user a proximity notification once the user is within a certain distance from the point interest.

Abstract: It is an object of the present invention to provide a method and system for enabling a simple and efficient method of directional arrows for the purpose of easily maneuvering throughout a contextual menu system (i.e., menus, text entry boxes, buttons, and the like) on a mobile device using limited input keys. In one embodiment, this allows a user to only require a rocker key with “directional arrows” and a select key, which is sometimes referred to as an “OK” or “Enter” key, to fully maneuver a menu and text entry system on a mobile device. This includes going forwards and backwards in the menu system tree, in addition to moving upwards and downwards in any menu list, all without needing to use any other keys. In another embodiment, this solution enables and illustrates a plurality of a-priori defined graphical pathways for the user to navigate.

Abstract: A portable fitness device includes a global positioning system (GPS) receiver that receives GPS signals, a wireless wide-area network transmitter supporting communication over-the-air to a wireless communication network, and a processing unit coupled to the GPS receiver and the wireless wide-area network transmitter. The processing unit receives the time-stamped waypoints from the GPS receiver and determines athletic performance information and route information from the time-stamped waypoints. The processing unit further outputs at least one of the athletic performance information and the route information to the wireless communication network during a human fitness activity via the wireless wide-area network transmitter.