Patents Assigned to INCELLA GMBH
  • Amino lipids, their synthesis and uses thereof
    Patent number: 9511024
    Abstract: The present invention provides new amino lipids and a convenient method for synthesizing these compounds. These (cationic) amino lipids have good properties as transfection agents. The method is an economic versatile two step synthesis allowing the preparation of various amino lipids thus leading to the assembly of a combinatorial library of transfection agents. Moreover, the present invention provides lipid particles (liposomes) containing said amino lipids and their use for delivering bioactive agents into cells. The invention encompasses also the use of lipid particles containing the cationic amino lipids as medicament.
    Type: Grant
    Filed: May 15, 2012
    Date of Patent: December 6, 2016
    Assignee: INCELLA GMBH
    Inventors: Gary Davidson, Pavel Levkin, Linxian Li, Yi Su, David Zahner
  • AMINO LIPIDS, THEIR SYNTHESIS AND USES THEREOF
    Publication number: 20140187614
    Abstract: The present invention provides new amino lipids and a convenient method for synthesising these compounds. These (cationic) amino lipids have good properties as transfection agents. The method is an economic versatile two step synthesis allowing the preparation of various amino lipids thus leading to the assembly of a combinatorial library of transfection agents. Moreover, the present invention provides lipid particles (liposomes) containing said amino lipids and their use for delivering bioactive agents into cells. The invention encompasses also the use of lipid particles containing the cationic amino lipids as medicament.
    Type: Application
    Filed: May 15, 2012
    Publication date: July 3, 2014
    Applicant: INCELLA GMBH
    Inventors: Gary Davidson, Pavel Levkin, Linxian Li, Yi Su, David Zahner