Abstract: Disclosed is a novel compound, and a cosmetic composition for whitening and a pharmaceutical composition for preventing and treating a melanin hyperpigmentation disorder by activating autophagy to induce melanosome degradation and also by effectively inhibiting endocytosis of keratinocytes to interfere melanosome transfer into keratinocytes, thereby expressing an excellent effect on improvement, prevention, and treatment of a hyperpigmentation disorder induced from melanin.
Type:
Grant
Filed:
June 18, 2019
Date of Patent:
April 14, 2020
Assignee:
INCOSPHARM CORPORATION
Inventors:
Hwa-Jee Chung, Myung Ho Kor, Heung Jae Kim, Sung Woo Kim, Seok Jeong Yoon, Ju Yeon Jung, Ka Young Shin, Se Kyoo Jeong, Kee Don Park
Abstract: Provided are a novel autophagy activation-inducing compound or salt thereof, and a use thereof, and particularly, a medicinal composition for treatment and prevention of neurodegenerative diseases, type II diabetes, or atopy or psoriasis dermatitis, a cosmetic composition for alleviation of aging or atopy or psoriasis dermatitis, and a food composition, including the compound capable of inducing autophagy activation or a pharmaceutically acceptable salt thereof.
Type:
Grant
Filed:
June 23, 2017
Date of Patent:
April 14, 2020
Assignee:
INCOSPHARM CORPORATION
Inventors:
Chaejin Lim, Heung Jae Kim, Hwa-Jee Chung, Juyeon Jung, Kayoung Shin, Beom Cheol Kim, Seok Jeong Yoon, Myung Ho Kor, Seon Deok Kwon, Keedon Park
Abstract: Provided are a cosmetic composition for anti-aging or alleviating skin redness, and a medicinal composition for treating and preventing skin inflammatory diseases caused by light, containing a compound inducing an increase in expression of adiponectin or a pharmaceutically acceptable salt thereof.
Type:
Grant
Filed:
April 20, 2018
Date of Patent:
November 5, 2019
Assignee:
Incospharm Corporation
Inventors:
Kee Don Park, Hwa-Jee Chung, Heung Jae Kim, Chae Jin Lim, Seok Jeong Yoon, Jong Phill Kang, Seon Deok Kwon, Myung Ho Kor, Ju Yeon Jung, Beom Cheol Kim, Ka Young Shin
Abstract: Provided are a novel autophagy activation-inducing compound or salt thereof, and a use thereof, and particularly, a medicinal composition for treatment and prevention of neurodegenerative diseases, type II diabetes, or atopy or psoriasis dermatitis, a cosmetic composition for alleviation of aging or atopy or psoriasis dermatitis, and a food composition, including the compound capable of inducing autophagy activation or a pharmaceutically acceptable salt thereof.
Type:
Application
Filed:
June 23, 2017
Publication date:
May 30, 2019
Applicant:
INCOSPHARM CORPORATION
Inventors:
Chaejin LIM, Heung Jae KIM, Hwa-Jee CHUNG, Juyeon JUNG, Kayoung SHIN, Beom Cheol KIM, Seok Jeong YOON, Myung Ho KOR, Seon Deok KWON, Keedon PARK
Abstract: Provided are a composition having anti-oxidant, anti-aging, and autophagy activities to thereby be useful for preventing, alleviating, or treating age-related metabolic diseases including neurodegenerative diseases or type 2 diabetes, and uses thereof.
Type:
Grant
Filed:
June 9, 2017
Date of Patent:
March 20, 2018
Assignee:
Incospharm Corporation
Inventors:
Chae Jin Lim, Myung Ho Kor, Seok Jeong Yoon, Jin A Kim, Heung Jae Kim, Kee Don Park
Abstract: Provided is Youngia denticulata extract being effective for prevention and treatment of diseases caused by an environmental pollution substance, and capable of protecting cell damage.
Type:
Application
Filed:
August 7, 2017
Publication date:
February 22, 2018
Applicant:
Incospharm Corporation
Inventors:
Chae Jin LIM, Seok Jeong YOON, Myung Ho KOR, Hwa-Jee CHUNG, Ju Yeon JUNG, Ka Young SHIN, Kee Don PARK
Abstract: The present invention relates to a peptide analog or a pharmaceutically acceptable salt thereof with excellent moisturizing effect, and use thereof for moisturization. More specifically, the present invention relates to a novel peptide analog or a pharmaceutically acceptable salt thereof, a method for preparation thereof, a moisturizing cosmetic composition comprising the same as an active ingredient, and a pharmaceutical composition for prevention and treatment of xeroderma.
Type:
Grant
Filed:
May 22, 2012
Date of Patent:
June 7, 2016
Assignee:
INCOSPHARM CORPORATION
Inventors:
Kee-Don Park, Chae-Jin Lim, Seok-Jeong Yoon, Seon-Deok Kwon
Abstract: The present invention relates to a biotin-conjugated hexapeptide-2 derivative or a pharmaceutically acceptable salt thereof and use thereof. More particularly, the present invention relates to a biotin-conjugated hexapeptide-2 derivative or a pharmaceutically acceptable salt thereof, a preparation method thereof, a composition including the same as an active ingredient, and a method for improving wrinkles and inhibiting skin aging using the same.
Type:
Grant
Filed:
March 27, 2013
Date of Patent:
November 10, 2015
Assignee:
INCOSPHARM CORPORATION
Inventors:
Kee-Don Park, Chae-Jin Lim, Seok-Jeong Yoon, Seon-Deok Kwon
Abstract: The present invention relates to a peptide analogue or a pharmaceutically acceptable salt thereof with excellent moisturizing effect, and use thereof for moisturization. More specifically, the present invention relates to a novel peptide analogue or a pharmaceutically acceptable salt thereof, a method for preparation thereof, a moisturizing cosmetic composition comprising the same as an active ingredient, and a pharmaceutical composition for prevention and treatment of xeroderma.
Type:
Application
Filed:
May 22, 2012
Publication date:
April 24, 2014
Applicant:
INCOSPHARM CORPORATION
Inventors:
Kee-Don Park, Chae-Jin Lim, Seok-Jeong Yoon, Seon-Deok Kwon