Patents Assigned to INCUMEDx, Inc.
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Patent number: 11819215Abstract: In various aspects, the invention relates to an embolic device for treating aneurysms or other vascular disorders that exhibits improved filling and/or neck blockage over conventional devices. As one example, the embolic device can include a structure that is wound into a spiral shape. In some cases, the spirally wound embolic device includes alternating narrow portions and link portions. As another example, the embolic device can be formed from a structure wound to form an infinity shape or, in some cases, multiple infinity shapes. In instances with multiple infinity shapes, the infinity shapes can be arranged either parallel or perpendicular to each other. In certain aspects, the embolic device can include two different embolic devices that are attached by an interconnect element, such that the two devices are attached but have independent freedom of motion when placed within a vascular disorder.Type: GrantFiled: April 4, 2019Date of Patent: November 21, 2023Assignee: INCUMEDx Inc.Inventors: Amiel R. Aguilar, Crystal K. Sein-Lwin, Nga Doan, Regina C. Velasco
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Patent number: 11090055Abstract: A device for delivering an implant (e.g., an embolic micro-coil) to a vascular disorder of a patient includes a delivery pusher, a moveable element, and first and second elongate members. The delivery pusher defines a lumen between its proximal and distal ends. The moveable element (e.g., a floating tube or a floating coil) defines a passageway therethrough and is disposed within the lumen of the delivery pusher. The first and second elongate members (e.g., core wires) are also disposed within the lumen of the delivery pusher. A portion of each elongate member passes through the passageway of the moveable element. Movement of the first elongate member in a first direction (e.g., retraction of the first elongate member from a locked to an unlocked configuration) causes a time-delayed or lost motion movement of the second elongate member in the same (i.e., first) direction, which releases the implant from the delivery pusher.Type: GrantFiled: April 6, 2018Date of Patent: August 17, 2021Assignee: INCUMEDx Inc.Inventors: Amiel Richard Aguilar, Crystal Kay Sein-Lwin, Nga Doan, Berchell John Yee
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Patent number: 11071551Abstract: An embolic device for treating aneurysms or other vascular disorders may be more compliant than conventional devices, while still achieving desired porosity. In particular, the device may achieve the desired porosity only at discrete sections along the length of the device where such a porosity is required (e.g., sections that will block the neck of the aneurysm upon deployment). The remaining sections of the device can be configured to increase the device's compliance. For example, the remaining sections can be formed from less material than the sections with the desired porosity. In some instances, the sections with the desired porosity are formed from mesh-screen segments and the remaining sections are formed from coil segments. In some instances, the mesh-screen segments are configured to further enhance the device's compliance. For example, the mesh-screen segment can be formed from a layered structure that achieves greater compliance than conventional braided structures.Type: GrantFiled: August 10, 2018Date of Patent: July 27, 2021Assignee: INCUMEDx, Inc.Inventors: Armando Garza, Be Thi Le, Tae Hee Cho, Regina Coeli Velasco
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Patent number: 10966727Abstract: A device for delivering an implant (e.g., an embolic micro-coil) to a vascular disorder of a patient includes a delivery pusher, a moveable element, and first and second elongate members. The delivery pusher defines a lumen between its proximal and distal ends. The moveable element (e.g., a floating tube or a floating coil) defines a passageway therethrough and is disposed within the lumen of the delivery pusher. The first and second elongate members (e.g., core wires) are also disposed within the lumen of the delivery pusher. A portion of each elongate member passes through the passageway of the moveable element. Movement of the first elongate member in a first direction (e.g., retraction of the first elongate member from a locked to an unlocked configuration) causes a time-delayed or lost motion movement of the second elongate member in the same (i.e., first) direction, which releases the implant from the delivery pusher.Type: GrantFiled: July 18, 2018Date of Patent: April 6, 2021Assignee: INCUMEDx, Inc.Inventors: Amiel Richard Aguilar, Crystal Kay Sein-Lwin, Nga Doan, Berchell John Yee
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Patent number: 10149676Abstract: A device for delivering an implant to a vascular disorder of a patient includes a delivery pusher. A stationary blade may be coupled to the delivery pusher. The stationary blade may include a sharp and stationary cutting component for cutting through a suture coupling the implant to the delivery pusher and for thereby releasing the implant when placed in proximity to the vascular disorder. In some cases, the strength of a junction connecting the suture to the implant is equal to or greater than the tensile strength of the suture itself. Additionally, or alternatively, a detachment handle may be fixedly and permanently attached to the delivery pusher such that a user of the device need not couple the detachment handle to the delivery pusher. The detachment handle may include a user manipulable component for initiating a mechanical release of the implant when placed in proximity to the vascular disorder.Type: GrantFiled: March 4, 2014Date of Patent: December 11, 2018Assignee: INCUMEDx, Inc.Inventors: Gregory Edwin Mirigian, Be Thi Le, Brendon James Bolos, Berchell John Yee, Amiel Richard Aguilar, Regina Coeli Velasco, Crystal Kay Sein Lwin, Liem Ho
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Patent number: 10098645Abstract: An embolic microcoil can be formed into a complex shape for use in treating aneurysms and other vascular disorders. The microcoil features a distal portion including several loops that together comprise a substantially spherical shape, and an elongated proximal portion that is deployable within the distal portion. The distal portion can create a stable frame with adequate loop coverage across a neck of the aneurysm. The proximal portion can include a series of substantially omega-shaped loops, which can apply a force against the interior of the substantially spherical shaped distal portion, expanding it into apposition with additional portions of the aneurysm wall. Methods of treating vascular disorders and methods of manufacturing certain microcoils are also disclosed.Type: GrantFiled: February 27, 2015Date of Patent: October 16, 2018Assignee: INCUMEDx, Inc.Inventors: Be T. Le, Armando Garza, Regina C. Velasco, Amiel R. Aguilar, Berchell J. Yee, Gregory E. Mirigian
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Patent number: 10052108Abstract: A device for delivering an implant (e.g., an embolic micro-coil) to a vascular disorder of a patient includes a delivery pusher, a moveable element, and first and second elongate members. The delivery pusher defines a lumen between its proximal and distal ends. The moveable element (e.g., a floating tube or a floating coil) defines a passageway therethrough and is disposed within the lumen of the delivery pusher. The first and second elongate members (e.g., core wires) are also disposed within the lumen of the delivery pusher. A portion of each elongate member passes through the passageway of the moveable element. Movement of the first elongate member in a first direction (e.g., retraction of the first elongate member from a locked to an unlocked configuration) causes a time-delayed or lost motion movement of the second elongate member in the same (i.e., first) direction, which releases the implant from the delivery pusher.Type: GrantFiled: October 30, 2015Date of Patent: August 21, 2018Assignee: INCUMEDx, Inc.Inventors: Amiel Richard Aguilar, Crystal Kay Sein-Lwin, Nga Doan, Berchell John Yee
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Patent number: 9987015Abstract: An embolic implant for treating aneurysms or other vascular disorders may include a cover component of unitary construction that is disposed about the exterior of a microcoil such that it does not extend into a lumen formed by the coil. The cover can enhance packing volume and density per unit length of coil, and can prevent blood flow and cause blood clotting while not risking rupture of the vascular disorder. The cover may also provide a platform for the application of multiple treatments and/or therapies including, for example, functionalized and/or bioactive coatings, drug coatings, gene therapy, thrombogenicity control coatings, and surface modifications, while preserving key coil performance attributes.Type: GrantFiled: July 24, 2015Date of Patent: June 5, 2018Assignee: INCUMEDx, Inc.Inventor: Armando Garza
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Patent number: 9980734Abstract: An embolic microcoil can be formed into a complex shape for use in treating aneurysms and other vascular disorders. The microcoil features a distal portion including several loops that together comprise a substantially spherical shape, and an elongated proximal portion that is deployable within the distal portion. The distal portion can create a stable frame with adequate loop coverage across a neck of the aneurysm. The proximal portion can include a series of substantially omega-shaped loops, which can apply a force against the interior of the substantially spherical shaped distal portion, expanding it into apposition with additional portions of the aneurysm wall. Methods of treating vascular disorders and methods of manufacturing certain microcoils are also disclosed.Type: GrantFiled: February 27, 2015Date of Patent: May 29, 2018Assignee: INCUMEDx, Inc.Inventors: Be T. Le, Armando Garza, Regina C. Velasco, Amiel R. Aguilar, Berchell J. Yee
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Patent number: 9936957Abstract: Disclosed is a micro-coil assembly including a micro-coil unit which is inserted into an aneurysm or other vascular malformation of a patient and prevents inflow of blood by inducing thrombus, a coil pusher unit which is arranged adjacent to the micro-coil unit and delivers the micro-coil unit to the aneurysm or other vascular malformation of the patient, a tensile wire which is relatively movably arranged in the coil pusher unit, a tie which connects the micro-coil unit and the tensile wire, and a tie cutting unit which is arranged adjacent to the coil pusher unit such that at least a part of the tie cutting unit is movable between a setting position for maintaining the tie in a tied state and a cutting position for cutting the tie, and cuts the tie when moved to the cutting position.Type: GrantFiled: May 30, 2014Date of Patent: April 10, 2018Assignee: INCUMEDx, Inc.Inventor: Ho Chang Kang
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Patent number: 9636118Abstract: An embolic microcoil can be formed into a complex shape for use in treating aneurysms and other vascular disorders. The microcoil features a distal portion including several loops that together comprise a substantially spherical shape, and an elongated proximal portion that is deployable within the distal portion. The distal portion can create a stable frame with adequate loop coverage across a neck of the aneurysm. The proximal portion can include a series of substantially omega-shaped loops, which can apply a force against the interior of the substantially spherical shaped distal portion, expanding it into apposition with additional portions of the aneurysm wall. Methods of treating vascular disorders and methods of manufacturing certain microcoils are also disclosed.Type: GrantFiled: February 27, 2015Date of Patent: May 2, 2017Assignee: INCUMEDx, Inc.Inventors: Armando Garza, Be T. Le, Regina C. Velasco, Amiel R. Aguilar, Berchell J. Yee
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Patent number: 9282971Abstract: A device for delivering an implant to a vascular disorder of a patient includes a delivery pusher. A stationary blade may be coupled to the delivery pusher. The stationary blade may include a sharp and stationary cutting component for cutting through a suture coupling the implant to the delivery pusher and for thereby releasing the implant when placed in proximity to the vascular disorder. In some cases, the strength of a junction connecting the suture to the implant is equal to or greater than the tensile strength of the suture itself. Additionally, or alternatively, a detachment handle may be fixedly and permanently attached to the delivery pusher such that a user of the device need not couple the detachment handle to the delivery pusher. The detachment handle may include a user manipulable component for initiating a mechanical release of the implant when placed in proximity to the vascular disorder.Type: GrantFiled: March 4, 2014Date of Patent: March 15, 2016Assignee: INCUMEDx, Inc.Inventors: Gregory Edwin Mirigian, Be Thi Le, Regina Coeli Velasco
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Publication number: 20160022275Abstract: An embolic implant for treating aneurysms or other vascular disorders may include a cover component of unitary construction that is disposed about the exterior of a microcoil such that it does not extend into a lumen formed by the coil. The cover can enhance packing volume and density per unit length of coil, and can prevent blood flow and cause blood clotting while not risking rupture of the vascular disorder. The cover may also provide a platform for the application of multiple treatments and/or therapies including, for example, functionalized and/or bioactive coatings, drug coatings, gene therapy, thrombogenicity control coatings, and surface modifications, while preserving key coil performance attributes.Type: ApplicationFiled: July 24, 2015Publication date: January 28, 2016Applicant: INCUMEDx, Inc.Inventor: Armando Garza