Patents Assigned to Incuron, LLC
  • Carbazole compounds and therapeutic uses of the compounds
    Patent number: 9566265
    Abstract: Compounds of the general structural formula (I) and (II) and use of the compounds and salts and hydrates thereof, as therapeutic agents are disclosed. Treatable diseases and conditions include cancers, inflammatory diseases and conditions, and immunodeficiency diseases. (I), (II).
    Type: Grant
    Filed: June 4, 2015
    Date of Patent: February 14, 2017
    Assignee: INCURON, LLC
    Inventors: John Tucker, Sergey Sviridov, Leonid Brodsky, Catherine Burkhart, Andrei Purmal, Katerina Gurova, Andrei Gudkov
  • METHODS OF MODULATING VARIOUS BIOMARKERS WITH CURAXINS
    Publication number: 20160303078
    Abstract: The present invention relates to improved methods for diagnosing and/or treating cancer with a curaxin, including curaxin 137.
    Type: Application
    Filed: December 10, 2014
    Publication date: October 20, 2016
    Applicant: Incuron, LLC
    Inventor: Ivan Bespalov
  • Curaxins for use in treating carcinogen-induced cancer
    Patent number: 9169207
    Abstract: The present invention relates to the treatment of breast cancer which is estrogen receptor positive (ER+) and/or human epidermal growth factor receptor 2 positive (HER2) and/or progesterone receptor positive (PR) and/or facilitates chromatin transcription positive (FACT+) with a curaxin, including curaxin 137. The present invention also pertains to a method of identifying a subject who has a breast cancer tumor and is likely to respond to treatment with a curaxin.
    Type: Grant
    Filed: March 27, 2013
    Date of Patent: October 27, 2015
    Assignee: Incuron, LLC
    Inventors: Andrei Gudkov, Katerina Gurova
  • Carbazole compounds and therapeutic uses of the compounds
    Patent number: 9108916
    Abstract: Compounds of the general structural formula (I) and (II) and use of the compounds and salts and hydrates thereof, as therapeutic agents are disclosed. Treatable diseases and conditions include cancers, inflammatory diseases and conditions, and immunodeficiency diseases. (I), (II).
    Type: Grant
    Filed: April 1, 2014
    Date of Patent: August 18, 2015
    Assignee: Incuron, LLC
    Inventors: John Tucker, Sergey Sviridov, Leonid Brodsky, Catherine Burkhart, Andrei Purmal, Katerina Gurova, Andrei Gudkov
  • CARBAZOLE COMPOUNDS AND THERAPEUTIC USES OF THE COMPOUNDS
    Publication number: 20140303224
    Abstract: Compounds of the general structural formula (I) and (II) and use of the compounds and salts and hydrates thereof, as therapeutic agents are disclosed. Treatable diseases and conditions include cancers, inflammatory diseases and conditions, and immunodeficiency diseases. (I), (II).
    Type: Application
    Filed: April 1, 2014
    Publication date: October 9, 2014
    Applicant: Incuron, LLC
    Inventors: John Tucker, Sergey Sviridov, Leonid Brodsky, Catherine Burkhart, Andrei Purmal, Katerina Gurova, Andrei Gudkov
  • Carbazole compounds and therapeutic uses of the compounds
    Patent number: 8765738
    Abstract: Compounds of the general structural formula (I) and (II) and use of the compounds and salts and hydrates thereof, as therapeutic agents are disclosed. Treatable diseases and conditions include cancers, inflammatory diseases and conditions, and immunodeficiency diseases.
    Type: Grant
    Filed: October 5, 2009
    Date of Patent: July 1, 2014
    Assignee: Incuron, LLC
    Inventors: John Tucker, Sergey Sviridov, Leonid Brodsky, Catherine Burkhart, Andrei Purmal, Katerina Gurova, Andrei Gudkov
  • Inducing cell death by inhibiting adaptive heat shock response
    Patent number: 8486697
    Abstract: Provided herein is a method for inducing cell death by inducing heat shock response in a cell in combination with inhibiting adaptive heat shock response. Also provided are methods for preventing cancer, treating intracellular parasite infections, and inflammation-associated conditions.
    Type: Grant
    Filed: May 20, 2009
    Date of Patent: July 16, 2013
    Assignees: Incuron, LLC, Health Research, Inc.
    Inventors: Andrei Gudkov, Nickolay Neznanov, Katerina Gurova