Patents Assigned to Incyte Pharmaceuticals
  • ATP-dependent RNA helicase protein
    Patent number: 6139837
    Abstract: The invention provides a human ATP-dependent RNA helicase (ADRH-1) and polynucleotides which identify and encode ADRH-1. The invention also provides expression vectors, host cells, agonists, antibodies and antagonists. The invention also provides methods for treating disorders associated with expression of ADRH-1.
    Type: Grant
    Filed: September 9, 1998
    Date of Patent: October 31, 2000
    Assignee: Incyte Pharmaceuticals, Inc.
    Inventors: Olga Bandman, Karl J. Guegler, Neil C. Corley, Purvi Shah
  • Human immune system associated molecules
    Patent number: 6135941
    Abstract: The invention provides human immune system associated proteins (HISAP) and polynucleotides which identify and encode HISAP. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for treating or preventing disorders associated with expression of HISAP.
    Type: Grant
    Filed: March 27, 1998
    Date of Patent: October 24, 2000
    Assignee: Incyte Pharmaceuticals, Inc.
    Inventors: Jennifer L. Hillman, Preeti Lal, Y. Tom Tang, Henry Yue, Janice Au-Young, Neil C. Corley, Karl J. Guegler, Mariah R. Baughn
  • Histone fusion protein
    Patent number: 6136314
    Abstract: The present invention provides a human histone fusion protein (HFP) and polynucleotides which identify and encode HFP. The invention also provides expression vectors, host cells, agonists, antibodies and antagonists. In addition, the invention also provides methods for producing HFP and for treating or preventing disorders associated with expression of HFP.
    Type: Grant
    Filed: July 14, 1999
    Date of Patent: October 24, 2000
    Assignee: Incyte Pharmaceuticals, Inc.
    Inventors: Jennifer L. Hillman, Surya K. Goli
  • Human SMT3-like protein
    Patent number: 6136955
    Abstract: The present invention provides a human SMT3-like protein (HSMTH) and polynucleotides which identify and encode HSMTH. The invention also provides expression vectors, host cells, agonists, antibodies and antagonists. In addition, the invention provides methods for producing HSMTH and for treating or preventing disorders associated with expression of HSMTH.
    Type: Grant
    Filed: October 14, 1998
    Date of Patent: October 24, 2000
    Assignee: Incyte Pharmaceuticals, Inc.
    Inventors: Jennifer L. Hillman, Purvi Shah
  • Human regulatory molecules
    Patent number: 6132973
    Abstract: The invention provides human regulatory molecules and polynucleotides (collectively designated HRM) which identify and encode them. The invention also provides expression vectors, host cells, agonists, antibodies and antagonists. The invention further provides methods for diagnosing, preventing, and treating disorders associated with expression of human regulatory molecules.
    Type: Grant
    Filed: January 20, 1999
    Date of Patent: October 17, 2000
    Assignee: Incyte Pharmaceuticals, Inc.
    Inventors: Preeti Lal, Jennifer L. Hillman, Olga Bandman, Purvi Shah, Janice Au-Young, Henry Yue, Karl J. Guegler, Neil C. Corley
  • Human growth-associated methyltransferases
    Patent number: 6132714
    Abstract: The invention provides a human growth-associated methyltransferase (GAMT) and polynucleotides which identify and encode GAMT. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for treating or preventing disorders associated with expression of GAMT.
    Type: Grant
    Filed: August 24, 1999
    Date of Patent: October 17, 2000
    Assignee: Incyte Pharmaceuticals, Inc.
    Inventors: Y. Tom Tang, Henry Yue, Karl J. Guegler, Purvi Shah
  • Hydrolase enzymes
    Patent number: 6132964
    Abstract: The invention provides human hydrolase-like molecules (HHLM) and polynucleotides which identify and encode HHLM. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for treating or preventing disorders associated with expression of HHLM.
    Type: Grant
    Filed: February 6, 1998
    Date of Patent: October 17, 2000
    Assignee: Incyte Pharmaceuticals, Inc.
    Inventors: Olga Bandman, Preeti Lal, Jennifer L. Hillman, Neil C. Corley, Karl J. Guegler, Purvi Shah
  • Human SMN-like protein
    Patent number: 6130064
    Abstract: The invention provides a human SMN-like protein (HSLP) and polynucleotides which identify and encode HSLP. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for treating or preventing disorders associated with expression of HSLP.
    Type: Grant
    Filed: February 24, 1998
    Date of Patent: October 10, 2000
    Assignee: Incyte Pharmaceuticals, Inc.
    Inventors: Y. Tom Tang, Neil C. Corley, Karl J. Guegler
  • Polynucleotide encoding human lysyl hydroxylase-like protein
    Patent number: 6130039
    Abstract: The invention provides a human lysyl hydroxylase-like protein (HLHLP) and polynucleotides which identify and encode HLHLP. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for treating or preventing disorders associated with expression of HLHLP.
    Type: Grant
    Filed: December 12, 1997
    Date of Patent: October 10, 2000
    Assignee: Incyte Pharmaceuticals, Inc.
    Inventors: Olga Bandman, Purvi Shah, Preeti Lal, Neil C. Corley
  • Human cytochrome P450
    Patent number: 6130077
    Abstract: The invention provides a human cytochrome P450 (HUCYP) and polynucleotides which identify and encode HUCYP. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating, or preventing disorders associated with expression of HUCYP.
    Type: Grant
    Filed: October 1, 1998
    Date of Patent: October 10, 2000
    Assignee: Incyte Pharmaceuticals, Inc.
    Inventors: Henry Yue, Karl J. Guegler, Neil C. Corley, Janice Au-Young
  • Human P24 vesicle proteins
    Patent number: 6130325
    Abstract: The present invention provides two human p24 vesicle trafficking proteins (designated individually as Hp24-1 and Hp24-2 and collectively as Hp24) and polynucleotides which identify and encode Hp24. The invention also provides genetically engineered expression vectors and host cells comprising the nucleic acid sequences encoding Hp24 and a method for producing Hp24. The invention also provides for agonists, antibodies, or antagonists specifically binding Hp24, and their use, in the prevention and treatment of diseases associated with expression of Hp24. Additionally, the invention provides for the use of antisense molecules to polynucleotides encoding Hp24 for the treatment of diseases associated with the expression of Hp24. The invention also provides diagnostic assays which utilize the polynucleotide, or fragments or the complement thereof, and antibodies specifically binding Hp24.
    Type: Grant
    Filed: February 14, 1997
    Date of Patent: October 10, 2000
    Assignee: Incyte Pharmaceuticals, Inc.
    Inventors: Surya K. Goli, Olga Bandman
  • Human fibrous protein
    Patent number: 6127146
    Abstract: The invention provides a human fibrous protein (FIBR) and polynucleotides which identify and encode FIBR. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for treating or preventing disorders associated with expression of FIBR.
    Type: Grant
    Filed: March 3, 1998
    Date of Patent: October 3, 2000
    Assignee: Incyte Pharmaceuticals, Inc.
    Inventors: Preeti Lal, Karl J. Guegler, Neil C. Corley
  • UBCH7-like ubiquitin-conjugating enzyme
    Patent number: 6124123
    Abstract: The present invention provides a human ubiquitin-conjugating enzyme (UBCPB) and polynucleotides which identify and encode UBCPB. The invention also provides genetically engineered expression vectors and host cells comprising the nucleic acid sequences encoding UBCPB and a method for producing UBCPB. The invention also provides for agonists, antibodies, or antagonists specifically binding UBCPB, and their use, in the prevention and treatment of diseases associated with expression of UBCPB. Additionally, the invention provides for the use of antisense molecules to polynucleotides encoding UBCPB for the treatment of diseases associated with the expression of UBCPB. The invention also provides diagnostic assays which utilize the polynucleotide, or fragments or the complement thereof, and antibodies specifically binding UBCPB.
    Type: Grant
    Filed: August 12, 1998
    Date of Patent: September 26, 2000
    Assignee: Incyte Pharmaceuticals, Inc.
    Inventors: Olga Bandman, Surya K. Goli
  • Human nucleotide pyrophosphohydrolase-2
    Patent number: 6124095
    Abstract: The invention provides a human nucleotide pyrophosphohydrolase-2 (NTPPH-2) and polynucleotides which identify and encode NTPPH-2. The invention also provides expression vectors, host cells, agonists, antibodies and antagonists. The invention also provides methods for treating disorders associated with expression of NTPPH-2.
    Type: Grant
    Filed: December 22, 1997
    Date of Patent: September 26, 2000
    Assignee: Incyte Pharmaceuticals, Inc.
    Inventors: Holly Magna, Paul Schaffer, Michael Lawton, Sue Yocum, Peter Mitchell, Nancy Hutchinson, Lynn E. Murry
  • Rab proteins
    Patent number: 6124116
    Abstract: The present invention provides four human Rab and Rab-associated proteins (designated collectively as HRAB) and polynucleotides which identify and encode HRAB. The invention also provides genetically engineered expression vectors and host cells comprising the nucleic acid sequences encoding HRAB and a method for producing HRAB. The invention also provides for use of HRAB and agonists, antibodies, or antagonists specifically binding HRAB, in the prevention and treatment of diseases associated with expression of HRAB. Additionally, the invention provides for the use of antisense molecules to polynucleotides encoding HRAB for the treatment of diseases associated with the expression of HRAB. The invention also provides diagnostic assays which utilize the polynucleotide, or fragments or the complement thereof, and antibodies specifically binding HRAB.
    Type: Grant
    Filed: October 29, 1996
    Date of Patent: September 26, 2000
    Assignee: Incyte Pharmaceuticals, Inc.
    Inventors: Olga Bandman, Janice Au-Young
  • Human Vps35/Mem3-related protein
    Patent number: 6124446
    Abstract: The invention provides a human Vps35/Mem3-related protein (hvmrp) and polynucleotides which identify and encode hvmrp. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for treating or preventing disorders associated with expression of hvmrp.
    Type: Grant
    Filed: January 8, 1998
    Date of Patent: September 26, 2000
    Assignee: Incyte Pharmaceuticals, Inc.
    Inventors: Jennifer L. Hillman, Neil C. Corley, Purvi Shah
  • Cell division regulators
    Patent number: 6121019
    Abstract: The invention provides three human cell division regulators (HCDR) and polynucleotides which identify and encode HCDR. The invention also provides expression vectors, host cells, agonists, antibodies and antagonists. The invention also provides methods for preventing and treating disorders associated with expression of HCDR.
    Type: Grant
    Filed: March 23, 1999
    Date of Patent: September 19, 2000
    Assignee: Incyte Pharmaceuticals, Inc.
    Inventors: Jennifer L. Hillman, Olga Bandman, Preeti Lal, Purvi Shah, Neil C. Corley
  • Human calcium-binding proteins
    Patent number: 6117989
    Abstract: The invention provides human calcium-binding proteins (CaBPs) and polynucleotides which identify and encode CaBP. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for treating or preventing disorders associated with expression of CaBP.
    Type: Grant
    Filed: March 26, 1998
    Date of Patent: September 12, 2000
    Assignee: Incyte Pharmaceuticals, Inc.
    Inventors: Olga Bandman, Jennifer L. Hillman, Neil C. Corley, Karl J. Guegler, Preeti Lal, Chandra Patterson
  • Human glycoprotein
    Patent number: 6113904
    Abstract: The present invention provides polynucleotides which identify and encode a novel human glycoprotein (SC2H). The invention provides for genetically engineered expression vectors and host cells comprising the nucleic acid sequence encoding SC2H. The invention also provides for the use of substantially purified SC2H and its agonists in the commercial production of recombinant proteins for the treatment of diseases associated with the expression of SC2H. Additionally, the invention provides for the use of antisense molecules to SC2H in the treatment of diseases associated with the expression of SC2H. The invention also describes diagnostic assays which utilize diagnostic compositions comprising the polynucleotides which hybridize with naturally occurring sequences encoding SC2H and antibodies which specifically bind to the protein.
    Type: Grant
    Filed: April 20, 1998
    Date of Patent: September 5, 2000
    Assignee: Incyte Pharmaceuticals, Inc.
    Inventors: Olga Bandman, Janice Au-Young, Phillip R. Hawkins, Jennifer L. Hillman
  • Comparative gene transcript analysis
    Patent number: 6114114
    Abstract: A method and system for quantifying the relative abundance of gene transcripts in a biological sample. One embodiment of the method generates high-throughput sequence-specific analysis of multiple RNAs or their corresponding cDNAs (gene transcript imaging analysis). Another embodiment of the method produces a gene transcript imaging analysis by the use of high-throughput CDNA sequence analysis. In addition, the gene transcript imaging can be used to detect or diagnose a particular biological state, disease, or condition which is correlated to the relative abundance of gene transcripts in a given cell or population of cells. The invention provides a method for comparing the gene transcript image analysis from two or more different biological samples in order to distinguish between the two samples and identify one or more genes which are differentially expressed between the two samples.
    Type: Grant
    Filed: July 29, 1994
    Date of Patent: September 5, 2000
    Assignee: Incyte Pharmaceuticals, Inc.
    Inventors: Jeffrey J. Seilhamer, Randal W. Scott