Abstract: The present invention relates to the use of esculoside alone or in combination with adenylate cyclase stimulators, such as forskolin or Salvia miltiorrhiza diterpenes and/or with phosphodiesterase inhibitors, such as apigenine-skeleton dimeric flavones, in topical formulations for the treatment of peripheral vasculopathies related to an impaired peripheral microcirculation, cellulitis or unesthetisms connected with a deposit of superfluous fat. For the reduction of the deposits of superfluous fat of any origin, the above mentioned products are advantageously also combined with caffeine, theophylline and derivatives thereof.
Type:
Grant
Filed:
July 6, 1995
Date of Patent:
October 21, 1997
Assignee:
Indena S.A.
Inventors:
Ezio Bombardelli, Aldo Cristoni, Paolo Morazzoni
Abstract: The present invention relates to novel formulations useful in the preventive and curative treatment of hair loss and of seborrhea, containing coumarins such as khellin, visnadin, esculoside or alkaloids such as raubasine, vincamine and derivatives thereof, combined with unsaturated and saturated fatty acids.
Type:
Grant
Filed:
July 6, 1995
Date of Patent:
September 9, 1997
Assignee:
Indena S.A.
Inventors:
Ezio Bombardelli, Aldo Cristoni, Paolo Morazzoni