Patents Assigned to INDIAN INSTITUTE OF TECHNOLOGY INDORE
  • Third generation tubulysin analogues and process of preparation thereof
    Patent number: 11518786
    Abstract: The present disclosure relates to a third generation tubulysin analogues and process of preparation thereof. The present disclosure also relates to a method of using these third generation tubulysin analogues for treatment of various diseases including cancer.
    Type: Grant
    Filed: March 11, 2021
    Date of Patent: December 6, 2022
    Assignee: INDIAN INSTITUTE OF TECHNOLOGY INDORE
    Inventors: Venkatesh Chelvam, Amit Pandit, Ramesh Reddy Baddipally, Kratika Yadav, Biswarup Pathak, Diptendu Roy
  • Metal-free solvent-free synthesis of fused-pyrido heterocycles and biomedical applications
    Patent number: 11427596
    Abstract: Embodiments herein provide fused-pyrido heterocycles such as azaindoles, carboline derivatives, furo[b]pyridines or furo[b]pyridine-isatin hybrids of Formula I. Embodiments also relate to a process for a synthesis of variety of complex pyrido-heterocycles The pyrido-heterocycles can be used for treating cancer (cervix, kidney, lung, breast and epidermal skin) and multi-drug resistant tuberculosis. These heterocycles can also be used as anti-biofilm agents against pathogenic strains, which will minimize the risk of secondary infections.
    Type: Grant
    Filed: July 17, 2020
    Date of Patent: August 30, 2022
    Assignee: INDIAN INSTITUTE OF TECHNOLOGY INDORE
    Inventors: Venkatesh Chelvam, Premansh Dudhe, Mena Asha Krishnan, Avinash Sonawane