Patents Assigned to Indiana University, Advanced Research and Technology Institute
  • Patent number: 6537797
    Abstract: The invention includes an isolated bacterium and a consortium of microorganisms including an isolated bacterium of the invention, which is capable of utilizing as a sole carbon source a polychlorinated biphenyl. The invention also includes a recombinant microorganism, such as a bacterium, a yeast or a bacteriophage, transfected with nucleic acid from an isolated bacterium of the invention, which is capable of utilizing as a sole carbon source a polychlorinated biphenyl. The invention also includes an isolated bacterium, which is capable of utilizing as a sole carbon source a chlorobenzoate. In addition, the invention includes an isolated nucleic acid and recombinant enzymes useful in the degradation of a polychlorinated biphenyl. The invention also includes methods for the bioremediation or enhancement of the bioremediation of a PCB-contaminated environment using the bacteria or microorganisms of the invention.
    Type: Grant
    Filed: March 31, 2000
    Date of Patent: March 25, 2003
    Assignee: Indiana University, Advanced Research and Technology Institute
    Inventors: Flynn W. Picardal, Sanggoo Kim
  • Publication number: 20030027152
    Abstract: The present invention relates to mammalian Lhx3 nucleic acids and proteins encoded thereby. More specifically, the invention discloses novel porcine and human Lhx3 genes and isoforms thereof. The invention further relates to genomic mapping of the human Lhx3 coding region to the subtelomeric region of Chromosome 9. The invention also relates to methods and kits relating to the nucleic and amino acids encoding Lhx3 and uses therefor.
    Type: Application
    Filed: August 17, 2001
    Publication date: February 6, 2003
    Applicant: Indiana University Advanced Research and Technology Institute
    Inventors: Simon J. Rhodes, Jeanne L. Bridwell, Bradley C. Meier, Gretchen E. Parker, Jeffrey R. Price, Aaron D. Showalter, Kyle W. Sloop
  • Patent number: 6040573
    Abstract: A technique to produce a device for generating an electric field is disclosed. This electric field may be customized to direct movement of charged particles in a predetermined manner. Moreover, this device is readily installed and removed from a charged particle analyzer to facilitate interchange with other devices capable of generating electric fields with different characteristics. The device may be provided by etching an electrically conductive layer clad to a flexible dielectric substrate to define a predetermined conductive pattern. This pattern is then oriented relative to a charged particle pathway and an electric potential applied to generate the desired electric field.
    Type: Grant
    Filed: September 25, 1997
    Date of Patent: March 21, 2000
    Assignee: Indiana University Advanced Research & Technology Institute Inc.
    Inventors: C. Ray Sporleder, David E. Clemmer
  • Patent number: 5693501
    Abstract: The present invention combines detection and identification of H. capsulatum in one step, eliminating the need to use DNA probes to react with PCR products in order to distinguish different types of fungi. The purpose of the invention is to provide compounds and methods to directly and specifically identify H. capsulatum in clinical specimens. Specifically, we provide a unique nucleotide sequence from the rRNA gene internal transcribed spacer region I (ITSI) of H. capsulatum and a PCR method which amplifies the unique sequence of H. capsulatum.
    Type: Grant
    Filed: March 8, 1995
    Date of Patent: December 2, 1997
    Assignee: Indiana University Advanced Research & Technology Institute
    Inventors: Chao-Hung Lee, Bingdong Jiang