Patents Assigned to Indiana University Research & Technology Corporation
  • Publication number: 20210031102
    Abstract: A physical device interface for a virtual reality system is provided, comprising: a microprocessor board including a microprocessor, a plurality of control outputs, a first communication port and a second communication port; a plurality of receptacles configured to provide power to a corresponding plurality of physical devices; and a power board coupled to the plurality of control outputs and the plurality of receptacles, the power board including a plurality of channels controlled by the plurality of control outputs to provide power to the plurality of receptacles. The first communication port is configured to communicate with a computer for configuration of the interface and the second communication port is configured to communicate with another interface.
    Type: Application
    Filed: February 16, 2017
    Publication date: February 4, 2021
    Applicant: Indiana University Research and Technology Corporation
    Inventor: Chauncey Eugene Frend
  • Publication number: 20210037052
    Abstract: A system comprising a processor in electrical communication with a network and a non-transitory memory having instructions that, in response to an execution by the processor, cause the processor to monitor a routing information base (“RIB”) of the network, identify a change in the RIB, calculate a probability of suspiciousness of the change in the RIB, and classify the change in the RIB based on a continuum of trust are disclosed. Methods of managing routers are also disclosed.
    Type: Application
    Filed: February 17, 2017
    Publication date: February 4, 2021
    Applicant: Indiana University Research and Technology Corporation
    Inventor: L. Jean Camp
  • Patent number: 10899829
    Abstract: EMAPII is a monocyte- and endothelial cell-activating protein with prominent pro-apoptotic activity on endothelial and epithelial cells. Provided herein are compositions and methods for treating or preventing endothelial and epithelial apoptosis induced by EMAPII. More particularly, provided herein are compositions and methods for treating or preventing Influenza A virus (IAV)-induced weight loss, impairment of blood oxygenation, lung edema, and endothelial/epithelial apoptosis associated with IAV infections. In addition, anti-EMAPII therapy provides a novel complementary treatment strategy to existing anti-viral and anti-inflammatory approaches.
    Type: Grant
    Filed: February 23, 2017
    Date of Patent: January 26, 2021
    Assignees: INDIANA UNIVERSITY RESEARCH AND TECHNOLOGY CORPORATION, THE UNITED STATES GOVERNMENT AS REPRESENTED BY THE DEPARTMENT OF VETERANS AFFAIRS
    Inventors: Natalia Bogatcheva, Matthias Alexander Clauss, Keith L. March
  • Publication number: 20210015983
    Abstract: Methods and devices for a self-contained device including a hydraulic motor and a hydraulic pump. Preferably, the motor is incorporated either within the interior of the pump, on the exterior of the pump, or a combination of the two. The pump increases the kinetic energy of the fluid by centrifugal means, and in some embodiments is a viscous impeller pump. Applications include building flow systems, industrial processes, and biological circulatory systems.
    Type: Application
    Filed: March 6, 2019
    Publication date: January 21, 2021
    Applicant: Indiana University Research and Technology Corporation
    Inventor: Mark D. RODEFELD
  • Patent number: 10888348
    Abstract: A scar subcision devices comprising a first elongated element comprising a pivotal connection to a second elongated element, the first elongated element having a blunt distal end, the second elongated element having a proximal-facing cutting edge at a distal end thereof, the device having a first state wherein the cutting edge is retracted to a location within an outer perimeter of the first elongated element, and a second state wherein the cutting edge is exposed outside of the outer perimeter of the first elongated element and the device transitioning between the first state and the second state by the first elongated element and the second elongated element rotating relative to each other about the pivotal connection are disclosed. Methods are also disclosed.
    Type: Grant
    Filed: February 6, 2020
    Date of Patent: January 12, 2021
    Assignee: Indiana University Research and Technology Corporation
    Inventors: Luke G. Gutwein, Rajiv Sood, Barry Davignon
  • Patent number: 10886540
    Abstract: Functionalized graphene comprising graphene, a metal dispersed throughout the graphene, wherein the metal comprises Pt, Rh, Pd, Ag, Au, Ni, Os, Ir, alloys thereof, oxides thereof, or mixtures thereof, and a first functional group covalently bonded to the graphene, wherein the first functional group comprises sulfonate, SO3?, Carboxylate, COO?, a tertiary amine, NR3+, where R is H, alkyl, aryl, or combinations thereof, polybenzimidazole (PBI), poly(ethylene oxide) (PEO), polyphenylene oxide (PPO), polyaniline, or mixtures thereof are disclosed. Methods of manufacture are also disclosed.
    Type: Grant
    Filed: December 13, 2016
    Date of Patent: January 5, 2021
    Assignee: Indiana University Research and Technology Corporation
    Inventors: Jian Xie, Zhe-Fei Li, Le Xin
  • Patent number: 10880330
    Abstract: System and method for detecting an infected website are disclosed. A semantic finder receives top-level domains and identifies keywords of the top-level domains representing a predetermined semantics. The keywords are compared with irrelevant bad terms to find at least one irrelevant term. An inconsistency searcher searches the top-level domains and detects at least one fully-qualified domain name carrying the at least one irrelevant term. A context analyzer evaluates context information associated with the irrelevant term, identifies at least one frequently-used term identified in the context information, and determines whether the at least one frequently-used term is unrelated to a generic content of the at least one fully-qualified domain name An irrelevant bad term collector extracts the at least one frequently-used term unrelated to the generic content and adds the extracted frequently-used term to an irrelevant bad term list for detecting the infected website.
    Type: Grant
    Filed: May 18, 2018
    Date of Patent: December 29, 2020
    Assignees: Indiana University Research & Technology Corporation, Georgia Tech Research Corporation
    Inventors: XiaoFeng Wang, Kan Yuan, Xiaojing Liao, Raheem A. Beyah
  • Publication number: 20200404327
    Abstract: In one example, a processing system including at least one processor may obtain at least one frame of a volumetric video, obtain a first viewport of a client device, render a plurality of two-dimensional subframes comprising two-dimensional projections of the at least one frame of the volumetric video, based upon the first viewport of the client device, and transmit the plurality of two-dimensional subframes to the client device. In another example, a processing system including at least one processor may request a volumetric video from a network-based proxy, provide a viewport to the network-based proxy, obtain a plurality of two-dimensional subframes from the network-based proxy in accordance with the viewport, select at least one of the plurality of two-dimensional subframes to present, and display the at least one two-dimensional subframe that is selected.
    Type: Application
    Filed: June 20, 2019
    Publication date: December 24, 2020
    Applicant: Indiana University Research and Technology Corporation
    Inventors: Bo Han, Jackson Jarrell Pair, Vijay Gopalakrishnan, Feng Qian
  • Patent number: 10864244
    Abstract: The present disclosure provides pharmaceutical compositions comprising rationally designed peptide analogs of the p65-TAD binding region of GILZ to selectively sequester activated p65. Structural and functional analyses suggest that select GILZ analog (GA) bind p65-TAD with optimum affinity, exhibit an estimated half minimal lethal dose comparable to known peptide drugs and suppress A?1-42 induced cytotoxicity. Furthermore, the present disclosure provides uses and methods of using the pharmaceutical compositions, and uses and methods of using pharmaceutical formulations comprising the pharmaceutical compositions, for the treatment of neurodegenerative diseases such as Alzheimer's Disease, Parkinson's Disease, multiple sclerosis, and amyotrophic lateral sclerosis (ALS).
    Type: Grant
    Filed: August 22, 2018
    Date of Patent: December 15, 2020
    Assignee: INDIANA UNIVERSITY RESEARCH AND TECHNOLOGY CORPORATION
    Inventors: Mythily Srinivasan, Debomoy Lahiri
  • Patent number: 10857209
    Abstract: Methods of cancer treatment are disclosed. Particularly, disclosed herein are methods of administering LAL and PPAR? ligands for treating various cancer patients to promote anti-cancer immunity (suppress MDSC), use for inhibiting tumor progression, and use for inhibiting tumor metastasis.
    Type: Grant
    Filed: February 10, 2017
    Date of Patent: December 8, 2020
    Assignee: Indiana University Research and Technology Corporation
    Inventors: Cong Yan, Hong Du
  • Patent number: 10858693
    Abstract: Biosensors and methods for localized surface plasmon resonance biosensing are disclosed. The biosensor can include a substrate having a substrate surface to which a plurality of localized surface plasmon resonance (LSPR) antennae are affixed. The LSPR antennae can be affixed via an affixation surface of the LSPR antenna. The LSPR antennae can have a functional surface opposite the affixation surface. Each functional surface can be functionalized by a plurality of single-stranded DNA.
    Type: Grant
    Filed: October 6, 2015
    Date of Patent: December 8, 2020
    Assignee: INDIANA UNIVERSITY RESEARCH & TECHNOLOGY CORPORATION
    Inventors: Rajesh Sardar, Murray Korc, Gayatri K. Joshi
  • Patent number: 10851335
    Abstract: In one embodiment, a flow assembly for cells comprises a first flow path configured to receive a plurality of cells, a second flow path configured to receive a buffer, and a third flow path configured to receive the plurality of cells and the buffer. The plurality of cells are in a single-file orientation and the buffer generally surrounds the single-file orientation of the plurality of cells when in the third flow path.
    Type: Grant
    Filed: March 31, 2016
    Date of Patent: December 1, 2020
    Assignee: Indiana University Research and Technology Corporation
    Inventors: Lisa M. Jones, Aimee Rinas
  • Patent number: 10849490
    Abstract: Methods are disclosed comprising measuring, with a first scanner, a central part of the visual image, measuring, with a second scanner, a peripheral part of the visual image, calculating, by a processor, a pan-retinal measure of image contrast for an extended area of the retina, and optimizing a pan-retinal visual quality. Methods further comprising optimizing a pan-retinal visual quality are also disclosed. Systems are also disclosed comprising either a scanner or a laser, a non-transitory memory having instructions that, in response to an execution by a processor, the processor receives a first measurement of the central part of the visual image, receives a second measurement of the peripheral part of the visual image, and calculates a pan-retinal measure of image contrast for an extended area of the retina. Methods of manufacturing lenses, including contact lenses are disclosed.
    Type: Grant
    Filed: August 25, 2016
    Date of Patent: December 1, 2020
    Assignee: Indiana University Research and Technology Corporation
    Inventors: Larry N. Thibos, Tao Liu
  • Publication number: 20200368259
    Abstract: Various aspects and embodiments disclosed herein relate generally to the modelling, treatment, reducing resistance to the treatment, prevention, and diagnosis of diseases/symptoms induced by multiple myeloma. Embodiments include methods of treating a bone related disease, comprising the steps of: administering to a subject at least one therapeutically effective dose of a compound disclosed herein.
    Type: Application
    Filed: August 2, 2018
    Publication date: November 26, 2020
    Applicants: Indiana University Research and Technology Corporation, University of Rochester, The United States of America As Represented by the Department of Veterans Affairs Office of General
    Inventors: Teresita M. Bellido, G. David Roodman, Jesus Delgado-Calle, Robert K. Boeckman, Frank H. Ebetino
  • Patent number: 10847126
    Abstract: A motor control system is provided for controlling a speed of a motor system used in a musical instrument. The motor control system includes at least one sensing device attached to the musical instrument, and configured for detecting movement of an object and providing a sensor signal based on the movement of the object. Also included in the motor control system is a control unit having a processor connected to the motor system and the at least one sensing device. The control unit is configured for selectively modulating the speed of the motor system based on the sensor signal.
    Type: Grant
    Filed: March 21, 2018
    Date of Patent: November 24, 2020
    Assignee: Indiana University Research and Technology Corporation
    Inventors: W. Scott Deal, Kevin David Galler, Maher Rizkalla, Paul Salama
  • Patent number: 10845337
    Abstract: A method for a structural characterization of polysaccharides, comprising steps of characterizing a polysaccharide by physical measurements comprising a determination of a mass of the polysaccharide by means of mass spectrometry, a further determination of a rotationally averaged cross section of the polysaccharide by means of ion mobility spectrometry, and an infrared spectrum of the polysaccharide by means of cryogenic, messenger-tagging IR spectroscopy.
    Type: Grant
    Filed: August 29, 2017
    Date of Patent: November 24, 2020
    Assignees: ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE (EPFL), INDIANA UNIVERSITY RESEARCH AND TECHNOLOGY CORPORATION
    Inventors: Thomas Rizzo, Chiara Masellis, Michael Zachary Kamrath, David Clemmer, Neelam Khanal
  • Patent number: 10828337
    Abstract: Materials and methods are disclosed for controlling vasculogenesis using building blocks of a collagen matrix and endothelial colony forming cells (ECFC). The building blocks may be isolated by fractionating an acid soluble Type I collagen. The building blocks comprising monomers and/or oligomers may be recombined in desired ratios to alter the matrix microenvironment and to influence ECFC behavior.
    Type: Grant
    Filed: February 7, 2018
    Date of Patent: November 10, 2020
    Assignee: Indiana University Research and Technology Corporation
    Inventors: Mervin C. Yoder, Paul Critser, Sherry Voytik-Harbin
  • Patent number: 10822318
    Abstract: The invention provides a compound of formula I: or a salt thereof, wherein R1, R2, R3, R4, L1, L2 and Y have any of the values described in the specification, as well as compositions comprising a compound of formula I. The compounds are useful for labeling penicillin-binding proteins (PBPs).
    Type: Grant
    Filed: May 24, 2018
    Date of Patent: November 3, 2020
    Assignees: Regents of the University of Minnesota, Indiana University Research and Technology Corporation
    Inventors: Erin Elizabeth Carlson, Shabnam Sharifzadeh, Alireza Shokri, Ozden Kocaoglu, Clayton L. Brown, Jr.
  • Patent number: 10823666
    Abstract: A method for determining a transmittance of light on oral tissue is provided, comprising: providing an LED; directing light from the LED onto a sample of oral tissue; measuring a first power of the light at a first surface of the sample; measuring a second power of the light at a second surface of the sample; computing surface loss of the light; and determining the transmittance of the light using the first power, the second power, and the surface loss.
    Type: Grant
    Filed: December 15, 2017
    Date of Patent: November 3, 2020
    Assignee: Indiana University Research and Technology Corporation
    Inventors: Jie Chen, Feifei Jiang
  • Patent number: 10820839
    Abstract: A system for recording visually guided motor activity within a bore of an MRI machine, comprising a tablet configured for mounting within the bore of the MRI machine, the tablet comprising a shielded housing, a touchscreen display mounted within the housing, and a receiver board, an interface box coupled to a controller configured to control operation of the touchscreen display, the interface box being located remotely from the bore and comprising a transmitter board for processing signals from the controller and transmitting processed signals to the receiver board of the tablet, and a cable connected between the tablet and the interface box, the cable comprising a plurality of conductors to carry signals between the receiver board and the transmitter board.
    Type: Grant
    Filed: February 4, 2019
    Date of Patent: November 3, 2020
    Assignee: Indiana University of Research and Technology Corporation
    Inventors: Jeffrey Sturgeon, Alexander Shroyer, Sophia Angela Vinci-Booher, Karin James