Patents Assigned to Industry-Acadmic Cooperation Foundation, Yonsei Univ.
  • Publication number: 20140142492
    Abstract: Provided is an electro-microneedle integrated body in which a dissolving microneedle and an electrode for electroporation are integrated into one, which enables a focused and efficient intracutaneous gene release for percutaneous gene delivery and intracellular gene delivery occurring in one in-situ treatment site The electro-microneedle integrated body according to the present invention includes an electrode for electroporation which is contacted with skin of a human body to apply an electric field pulse, including a base part and a plurality of electrode parts protruding from the base part, and a microneedle adhered to each electrode part and inserted into the skin of a human body, including a biocompatible and biodegradable viscous material and a genetic material, wherein the microneedle degrades within the skin, and the electric field pulse is applied through the electrode for electroporation in a site in which the microneedle is inserted.
    Type: Application
    Filed: January 24, 2014
    Publication date: May 22, 2014
    Applicants: Industry-Acadmic Cooperation Foundation, Yonsei Univ., Raphas Co., Ltd.
    Inventors: Hyungil Jung, Kwang Lee, Do Hyeon Jeong, Jung Dong Kim