Patents Assigned to INDUSTRY-UNIVERSITY COOPERATION FOUNDATION YONSEI
  • GENETIC POLYMORPHISMS IN THE CYTOCHROME P450 GENE WITH CLOPIDOGREL RESISTANCE
    Publication number: 20110159479
    Abstract: The present invention relates to a method for predicting the resistance of a human subject to clopidogrel, which comprises detecting the presence or absence of a A allele at position 636 of exon 4 in the CYP2C19 gene, wherein the presence of the A allele is indicative of a clopidogrel resistance. The present method may be very useful in predicting the resistance of a human subject to clopidogrel and contribute to more effective chemotherapy for patients having coronary artery disease and drug-eluting stent.
    Type: Application
    Filed: December 28, 2009
    Publication date: June 30, 2011
    Applicant: Industry-University Cooperation Foundation Yonsei University
    Inventors: Yang Soo Jang, Dongjik Shin, Sungha Park, Jungmyung Lee, Chiyoung Shim
  • Decorin Gene Delivery System And Cancer Treatment
    Publication number: 20080132449
    Abstract: A novel gene delivery system and recombinant adenovirus includes a decorin-encoding sequence to enhance transduction efficiency of transgenes. A pharmaceutical anti-tumor composition includes the recombinant adenovirus, as well as a pharmaceutical composition having improved tissue penetration potency and a pharmaceutical composition for treating a disease or disorder associated with accumulation of excess extracellular matrix.
    Type: Application
    Filed: February 24, 2006
    Publication date: June 5, 2008
    Applicant: Industry-University Cooperation Foundation Yonsei University
    Inventors: Chae-Ok Yun, Joo-Hang Kim
  • Gene Delivery System Containing Relaxin Gene And Pharmaceutical Composition Using Relaxin
    Publication number: 20070202080
    Abstract: The present invention relates to a novel gene delivery system and recombinant adenovirus comprising the relaxin-encoding sequence to enhance transduction efficiency of transgenes, a pharmaceutical anti-tumor composition comprising the recombinant adenovirus, a pharmaceutical composition having improved tissue penetration potency and a pharmaceutical composition for treating a disease or disorder associated with accumulation of excess extracellular matrix.
    Type: Application
    Filed: March 30, 2005
    Publication date: August 30, 2007
    Applicant: INDUSTRY-UNIVERSITY COOPERATION FOUNDATION YONSEI
    Inventors: Chae-Ok Yun, Joo-Hang Kim