Patents Assigned to Infinitus (China) Company Ltd.
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Publication number: 20210106642Abstract: The present invention relates to a composition having an anti-glycation effect and an application thereof. The anti-glycation composition includes the following constituents in parts by mass: 0.1 to 5 parts of Osmanthus fragrans extract, 0.1 to 5 parts of Punica granatum extract and 0.1 to 2 part of Olea europaea extract, wherein in the Osmanthus fragrans extract, a mass content of polyphenol is more than or equal to 10%, and a mass content of verbascoside is more than or equal to 10%; in the Punica granatum extract, a mass content of polyphenol is more than or equal to 30%, and a mass content of punicalagin is more than or equal to 8%; and in the Olea europaea extract, a mass content of polyphenol is more than or equal to 10%, and a mass content of hydroxytyrosol is more than or equal to 3%.Type: ApplicationFiled: December 11, 2019Publication date: April 15, 2021Applicant: INFINITUS (CHINA) COMPANY LTD.Inventors: Xiaoling WANG, Huawei ZHU, Zhen LUO, Jian TANG
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Patent number: 10968495Abstract: Provided is a strain CCFM8631 of Lactobacillus reuteri and use thereof. The strain CCFM8631 of Lactobacillus reuteri can significantly increase neurotransmitter 5-hydroxytryptamine level in peripheral blood, recover the hormone levels, for example testosterone and so on in peripheral blood of rat, normalize abnormal abundances of Blautia genus and Turicibacter genus, Oscillospira genus and Bifidobacterium genus in intestinal flora of rat affected by high-fat high-starch diet, show good tolerance to simulated gastrointestinal fluid and quickly colonize in intestinal, significantly improve pathological damages of tissues such as liver, duodenum and so on, and increase triglyceride and total cholesterol levels in serum and oral glucose tolerance of rat with metabolic syndrome caused by high-fat high-starch diet.Type: GrantFiled: August 23, 2018Date of Patent: April 6, 2021Assignee: INFINITUS (CHINA) COMPANY LTD.Inventors: Fangli Ma, Wei Chen, Gang Wang, Guangsu Zhu, Yuanyuan Wang, Lingyun Xiao, Minghua Hu, Hao Zhang, Jianxin Zhao, Chung Wah Ma
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Patent number: 10967016Abstract: The present disclosure relates to the field of drugs and health foods. Disclosed is a traditional Chinese medicine composition comprising GANODERMA polysaccharide, MORINDAE OFFICINALIS RADIX polysaccharide, POLYGONATI RHIZOMA polysaccharide, ANGELICAE SINENSIS RADIX oil and MYRISTICAE SEMEN oil. Experiments show that the traditional Chinese medicine composition has a scientific formulation, synergistic functions, without toxic and side effects, and not only has nutritional value but also inhibits the growth of tumor. Comparing with individual components, the composition significantly increases the percentages of CD4+ and CD8+ cells in lymphocytes of the tumor stroma, enhances body immune function, restores normal immune surveillance function, decreases VEGF and TGF-?1 positive cells in tumor tissue, assists in treating tumor, increases antitumor effects of chemotherapy drugs, improves immune status of body, has the function of restoring normal immune surveillance, preventing and assisting in treating tumor.Type: GrantFiled: August 8, 2018Date of Patent: April 6, 2021Assignee: INFINITUS (CHINA) COMPANY LTD.Inventors: Yuanyuan Wang, Fangli Ma, Renhuai Cong, Minghua Hu, Chung Wah Ma
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Patent number: 10967017Abstract: The present disclosure relates to the field of drugs and health foods. Disclosed is a traditional Chinese medicine composition comprising GANODERMA polysaccharide, GRIFOLA FRONDOSA polysaccharide, ANGELICAE SINENSIS RADIX oil and CINNAMOMI CORTEX oil. Experiments show that the traditional Chinese medicine composition has a scientific formulation, synergistic functions, without toxic and side effects, and not only has nutritional value but also inhibits the growth of tumor. Comparing with individual components, the composition significantly increases the percentages of CD4+ and CD8+ cells in lymphocytes of the tumor stroma, increases body immune function, recovers normal immune surveillance function, decreases the expression rate of VEGF and TGF-? 1 positive cells in tumor tissue, assists in treating tumor, increases antitumor effects of chemotherapy drugs, improves immune status of body, has the function of restoring normal immune surveillance, preventing and assisting in treating tumor.Type: GrantFiled: August 9, 2018Date of Patent: April 6, 2021Assignee: INFINITUS (CHINA) COMPANY LTD.Inventors: Minghua Hu, Fangli Ma, Yuanyuan Wang, Chung Wah Ma, Renhuai Cong, Lingyun Xiao
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Powder formulation having hypoglycemic and hypolipidemic functions and method for preparing the same
Patent number: 10960044Abstract: The present disclosure relates to the field of health care products, disclosing a powder made from inulin, FOLIUM CYCLOCARYA PALIURUS, RHIZOMA DIOSCOREA OPPOSITE, RADIX ASTRAGALUS MEMBRANACEUS, CAULIS DENDROBIUM and RADIX ET RHIZOMA SALVIA MILTIORRHIZA. The raw materials of the powder are all from natural Chinese herbal medicine without addition of excipient. In addition, dosage required for the powder is small; it can be directly dissolved in water for taking; it is soluble in cold water and can be absorbed quickly. The method for preparing the powder in the present disclosure is simple and suitable for large-scale production. Also, it is easy to be carried. The powder obtained has a good stability and long storage time. Experiments show that the powder of the present disclosure has greatly hypoglycemic and hypolipidemic effects, therefore can be used to prepare the health care foods having hypoglycemic and hypolipidemic effect.Type: GrantFiled: July 9, 2018Date of Patent: March 30, 2021Assignee: INFINITUS (CHINA) COMPANY LTD.Inventors: Fang Lv, Hongwei Zhao, Qingtao Tang -
Patent number: 10960039Abstract: The present disclosure relates to the technical field of health care products and foodstuffs, in particular to a composition, a preparation method, and the use thereof in preparation of products for relieving thyroid nodules. The composition provided by the invention uses AtractylodisMacrocephalaeRhizoma and ChuanxiongRhizoma as raw materials, which show synergistic effect through rational combination. Experiments show that the composition provided by the invention can improve thyroid epithelial cell proliferation and reduce the thyroid index of thyroid nodules, and has the advantages of relieving thyroid nodules and protecting thyroid function. The invention has the advantages of simple combination, high safety, simple and easy handling and definite cure effect.Type: GrantFiled: January 12, 2018Date of Patent: March 30, 2021Assignee: INFINITUS (CHINA) COMPANY LTD.Inventors: Lingyun Xiao, Renhuai Cong, Yuanyuan Wang, Fangli Ma, Chung Wah Ma
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Patent number: 10869901Abstract: The present disclosure relates to pharmaceutical field, providing a hydrolyzed chicken sternal cartilage extract, method for producing the same and use thereof. The hydrolyzed chicken sternal cartilage extract has a type II collagen content of ?50% and a chondroitin sulfate content of ?20%. In China, a huge amount of livestock and poultry are consumed, and the total consumption almost reaches ΒΌ of the worldwide livestock and poultry consumption. Chicken sternal cartilage is one of the main by-products in broiler chicken processing. In the present disclosure, a hydrolyzed chicken sternal cartilage extract rich in type II collagen and chondroitin sulfate is obtained by using biological enzymatic hydrolysis technique. Experiments results show that the hydrolyzed chicken sternal cartilage extract produced by the present disclosure has a good anti-inflammatory effect and can be used to prepare medications for treating osteoarthritis.Type: GrantFiled: March 18, 2019Date of Patent: December 22, 2020Assignee: INFINITUS (CHINA) COMPANY LTD.Inventors: Liugang Ding, Yong Zhou, Zhongbao Yue, Danlin He
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Patent number: 10869948Abstract: Disclosed is a composition of a collagen peptide and an elastin peptide, method of producing the same and use thereof. The composition of the present disclosure consists of a collagen peptide and an elastin peptide; the collagen peptide is prepared by enzymatic hydrolysis of a collagen material with pepsin or trypsin, and the elastin peptide is prepared by enzymatic hydrolysis of an elastin material with papain and/or protease Protamex. In the present disclosure, an elastin peptide and a collagen peptide with molecular weight in a specific range are prepared by specific processes, and the composition composed of the two at a suitable ratio can simultaneously and significantly increase the amount of the elastin and collagen in a damaged skin in a small usage amount, and significantly increase the content of hyaluronic acid and hydroxyproline while decrease the content of MMP3, meanwhile, inhibit skin inflammatory factors.Type: GrantFiled: May 16, 2019Date of Patent: December 22, 2020Assignee: INFINITUS (CHINA) COMPANY LTD.Inventors: Huawei Zhu, Xiaoling Wang, Liugang Ding, Xiaolei Guo, Yazhong Ge
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Publication number: 20200370078Abstract: Provided is a method of producing an oil containing polyunsaturated fatty acids by using Schizochytrium sp. The method comprises: performing fermentation using Schizochytrium sp.; resuspending the resultant cells after fermentation in water, adding cellulase and neutral protease for enzymolysis; mixing the enzymatic hydrolyzate with n-hexane, shaking, extracting, centrifuging, and collecting the n-hexane phase; concentrating the n-hexane phase under reduced pressure to remove the n-hexane, and drying to obtain an oil; performing a first crystallization and a second crystallization, and then performing cold filtration to obtain a liquid oil after the second crystallization; and subjecting the liquid oil to deacidification and decolorization. By regulating fermentation conditions and conducting concentration processing on polyunsaturated fatty acids, the content of eicosapentaenoic acid in the Schizochytrium sp.Type: ApplicationFiled: May 20, 2020Publication date: November 26, 2020Applicant: INFINITUS (CHINA) COMPANY LTD.Inventors: Zehua CHEN, Yong ZHOU, Jian TANG, Yonghua WANG, Zheng XIAO, Chenfeng JING, Dong LIANG
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Patent number: 10821149Abstract: The present invention relates to the pharmaceutical field, particularly to a composition and the use thereof. The composition serves to lower uric acid through the combination of several traditional Chinese medicines of Smilacis glabra rhizoma, Cichorii herba, Plantaginis herba and Coicis semen. On the basis of the combination of the traditional Chinese medicines described above, the addition of Alismatis rhizoma is able to improve the effect of lowering uric acid more significantly. Further, on the basis of the combination of the traditional Chinese medicines described above, the addition of tuna was able to improve the effect of lowering uric acid more significantly. A comprehensive analysis of the experimental results described above indicates that the compositions provided in the present invention have a significant effect of lowering uric acid.Type: GrantFiled: June 7, 2016Date of Patent: November 3, 2020Assignee: INFINITUS (CHINA) COMPANY LTD.Inventors: Bin Shi, Xiaolei Guo, Chung Wah Ma, Chuixin Qin, Zhen Luo, Wei Zhang
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Patent number: 10820615Abstract: The present disclosure belongs to the field of health care products, disclosing a powder formulation having a function of enhancing immunity, method for preparing the same and use thereof. The powder formulation is made from inulin, LYCII FRUCTUS, PORIA, LENTINUS EDODES (BERK.) SING, MORI FRUCTUS, CHRYSANTHEMI FLOS, CODONOPSIS RADIX, FLAMMULINA VELUTIPES, FRUIT BODY HERICIUM ERINACEUS and TREMELLA FUCIFORMIS. The starting materials of the powder formulation are all from natural Chinese herbal medicine without addition of excipient. The method for preparing the powder formulation in the present disclosure is simple and suitable for large-scale production. The powder formulation obtained has a good stability, long storage time, good taste. Experiments show that the powder formulation of the present disclosure can significantly enhance immunity, therefore can be used to prepare the health care foods having a function of improving immunity.Type: GrantFiled: July 10, 2018Date of Patent: November 3, 2020Assignee: INFINITUS (CHINA) COMPANY LTD.Inventors: Ruiqi He, Hongwei Zhao, Qingtao Tang
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Patent number: 10821146Abstract: The present disclosure belongs to the field of health care products, disclosing a powder formulation made from inulin, Auricularia, PORIA, LYCII FRUCTUS, MORI FRUCTUS, LONGAN ARILLUS, soy peptide powder, COICIS SEMEN, NELUMBINIS SEMEN and JUJUBAE FRUCTUS. The starting materials of the powder formulation are all from natural Chinese herbal medicine without addition of excipient. In addition, dose required for the powder formulation is small; it is easy to be taken and can be dissolved in water; it is soluble in cold water and can be absorbed quickly. The method for preparing the powder formulation in the present disclosure is simple and suitable for large-scale production. The powder formulation obtained has a good stability, long storage time, good taste. Experiments show that the powder formulation of the present disclosure can significantly enhance immunity, therefore can be used to prepare the health care foods having function on improving immunity.Type: GrantFiled: July 1, 2018Date of Patent: November 3, 2020Assignee: INFINITUS (CHINA) COMPANY LTD.Inventors: Lei Wang, Ruiqi He, Hongwei Zhao, Qingtao Tang
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Patent number: 10813961Abstract: The present disclosure relates to the field of health care products, disclosing a powder formulation made from inulin, GANODERMA, COICIS SEMEN, PORIA, ATRACTYLODIS MACROCEPHALAE RHIZOMA, CUSCUTAE SEMEN, POLYGONATI RHIZOMA, OPHIOPOGONIS RADIX, GLYCYRRHIZAE RADIX ET RHIZOMA, LYCII FRUCTUS, SCHISANDRAE CHINENSIS FRUCTUS and stevioside. The raw materials of the powder formulation are all from natural Chinese herbal medicine without addition of excipient. In addition, dose required for the powder formulation is small; it is easy to be taken and can be dissolved in water; it is soluble in cold water and can be absorbed quickly. The method for preparing the powder formulation is simple and suitable for large-scale production. The powder formulation obtained has a good stability, long storage time, good taste. Experiments show that the powder formulation of the present disclosure can significantly enhance immunity, therefore can be used to prepare the health care foods having function on improving immunity.Type: GrantFiled: June 30, 2018Date of Patent: October 27, 2020Assignee: INFINITUS (CHINA) COMPANY LTD.Inventors: Ruiqi He, Hongwei Zhao, Qingtao Tang
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Patent number: 10799549Abstract: Disclosed is a method of preparing a hepatoprotective traditional Chinese medicine composition. The composition is prepared from Fructus Ligustri Lucidi, Herba Ecliptae, Radix Paeoniae Alba, Rhizoma Curcumae Longae and clam as main raw materials.Type: GrantFiled: May 15, 2019Date of Patent: October 13, 2020Assignee: INFINITUS (CHINA) COMPANY LTD.Inventors: Yong Zhou, Hailong Li, Xiaolei Guo, Chung Wah Ma
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Publication number: 20200261515Abstract: The present disclosure relates to the field of microbial technology, and discloses a probiotic composition and use thereof. The probiotic composition in the present disclosure is consisted of Bifidobacterium adolescentis CCFM8630, Lactobacillus reuteri CCFM8631 and Lactobacillus rhamnosus CCFM1044, whose effect of alleviating metabolic syndrome is significantly better than that of CCFM8630 or CCFM8631 alone or combination of the two, especially in aspects of lowering epididymal fat content, lowering fasting blood glucose level, lowering the area under sugar tolerance curve and lowering contents of serum low density lipoprotein and total cholesterol, improving liver antioxidant capacity and lowering serum IL-1? content, etc. The extent of decrease or increase is increased by 9.62% to 769.62% compared with formulations of a single probiotic or a combination of two probiotics. The combination of three probiotics achieves a significant synergistic effect.Type: ApplicationFiled: July 24, 2019Publication date: August 20, 2020Applicant: INFINITUS (CHINA) COMPANY LTD.Inventors: Yuanyuan WANG, Wei CHEN, Gang WANG, Xiaofeng ZHU, Fangli MA, Junyong XIAO, Hao ZHANG, Jianxin ZHAO
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Publication number: 20200261519Abstract: The present disclosure relates to the field of microbial technology, and discloses a composite probiotics and the use thereof. The composite probiotics in the present disclosure is consisted of Bifidobacterium adolescentis CCFM8630, Lactobacillus reuteri CCFM8631, Lactobacillus rhamnosus CCFM1044 and Lactobacillus casei CCFM711, whose effect of alleviating metabolic syndrome is significantly better than that of CCFM8630 or CCFM8631 alone or combination of the two, especially in aspects of lowering contents of serum low density lipoprotein, total cholesterol, and liver triglyceride and contents of serum alanine aminotransferase, aspartate aminotransferase, alkaline phosphatase and IFN-?, and increasing contents of liver glutathione and superoxide dismutase, etc. The extent of decrease or increase is increased by 7.91% to 837.31% compared with the formulations of CCFM8630 or CCFM8631 alone or combination of the two probiotics. The combination of the four probiotics can achieve a significant synergistic effect.Type: ApplicationFiled: July 24, 2019Publication date: August 20, 2020Applicant: INFINITUS (CHINA) COMPANY LTD.Inventors: Fangli MA, Wei CHEN, Gang WANG, Xiaofeng ZHU, Yuanyuan WANG, Junyong XIAO, Hao ZHANG, Jianxin ZHAO
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Patent number: 10744173Abstract: The present invention relates to the technical field of health-care product, and in particular relates to a traditional Chinese medicine composition having a function of regulating emotions, a process for preparing the same, and a product thereof. It was found that the composition of the present invention had effects of nourishing liver and kidney, regulating Yin and Yang, tonifying Qi and nourishing blood, regulating emotions, and protecting the function of autonomic nerve, and could improve pressure-induced anxiety and depression, inattention, poor spirit, dispirited, learning and memory capacity decline, etc. The invention has the advantages of specificity and remarkable effect, and it uses all natural medicinal and edible plants as raw materials, the combination of which is simple, safe and stable, and is suitable for long-term use.Type: GrantFiled: January 29, 2018Date of Patent: August 18, 2020Assignee: INFINITUS (CHINA) COMPANY LTD.Inventors: Lingyun Xiao, Renhuai Cong, Minghua Hu, Yuanyuan Wang, Fangli Ma, Chung Wah Ma
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Patent number: 10729736Abstract: The present invention discloses a blood lipid-reducing composition, the active components of the composition are composed of fish oil, linseed oil, phytosterol ester or phytosterol. The composition mainly comprises components such as ?-linolenic acid, EPA, DHA and phytosterol or phytosterol ester, can reduce serum total cholesterol (TC), triglyceride (TG) and low-density lipoprotein cholesterol (LDL-C), has an efficacy of reducing blood lipid. The present invention also discloses the use of the blood lipid-reducing composition in the manufacture of health food having a function of reducing blood lipid.Type: GrantFiled: February 6, 2015Date of Patent: August 4, 2020Assignee: INFINITUS (CHINA) COMPANY LTD.Inventors: Jialing Ning, Yiting Yang, Zehua Chen
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Publication number: 20200222585Abstract: Disclosed is a composition of a collagen peptide and an elastin peptide, method of producing the same and use thereof. The composition of the present disclosure consists of a collagen peptide and an elastin peptide; the collagen peptide is prepared by enzymatic hydrolysis of a collagen material with pepsin or trypsin, and the elastin peptide is prepared by enzymatic hydrolysis of an elastin material with papain and/or protease Protamex. In the present disclosure, an elastin peptide and a collagen peptide with molecular weight in a specific range are prepared by specific processes, and the composition composed of the two at a suitable ratio can simultaneously and significantly increase the amount of the elastin and collagen in a damaged skin in a small usage amount, and significantly increase the content of hyaluronic acid and hydroxyproline while decrease the content of MMP3, meanwhile, inhibit skin inflammatory factors.Type: ApplicationFiled: May 16, 2019Publication date: July 16, 2020Applicant: INFINITUS (CHINA) COMPANY LTD.Inventors: Huawei ZHU, Xiaoling WANG, Liugang DING, Xiaolei GUO, Yazhong GE
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Publication number: 20200206296Abstract: The present invention relates to the field of health care food technology, specifically to a traditional Chinese medicine composition with a function of protecting joints, a use thereof, a method for producing the same and a health care food thereof. The Chinese medicine composition comprises CURCUMAE LONGAE RHIZOMA extract, cartilage extract, COICIS SEMEN extract and PUERARIAE LOBATAE RADIX extract. The composition of the present disclosure has a reasonable formulation, and the ingredients cooperate with each other to achieve functions of reducing arthrocele degree, decreasing arthritis index, ameliorating biochemical index of arthritis and reducing articular cavity area through various paths and at various levels.Type: ApplicationFiled: May 17, 2019Publication date: July 2, 2020Applicant: INFINITUS (CHINA) COMPANY LTD.Inventors: Liugang DING, Zhongbao YUE, Danlin HE, Yong ZHOU, Jian TANG