Abstract: The tubing includes an open-loop extracorporal circulation duct that has two parts, whereby one part extracts the blood to be purified and the other returns the purified blood; at least one duct connects at least one of the parts to a substitution solution source; a bubble trap disposed along the loop; a duct for evacuating the rejected product and provided with a segment tubing; and connecting elements for detachable interconnection of the respective extremities of the open-loop extracorporal circulation tubing to form a closed loop. The duct for evacuating the rejected product includes downstream from the segment tubing a blood detector and a connecting duct that extends between the downstream extremity of the segment tubing and the bubble trap.

Abstract: An extra-corporeal blood purification device includes a blood filter, and elements for measuring at least one parameter affected by filter resistance to liquid flow, elements for determining at least a threshold value of the parameter, elements for comparing the parameter with the threshold value, exchange control elements for calculating the distribution between the respective flow rates through connecting ducts, capable of reducing the difference between the value of the measured parameter and the threshold value.