Patents Assigned to Ingeneron Incorporated
  • Patent number: 9675673
    Abstract: Methods, apparatus and compositions are provided for treatment of cancer of a selected organ by intraluminal delivery of oncolytic agents through a blood vessel or duct leading to the cancer tissue. During the time the oncolytic agents are being applied to the targeted tissue downstream, the designated vessel or duct can be selectively occluded to increase concentration and pressure of the applied agents at the target site. Oncolytic compositions including oncolytic viruses formulated with delivery visualization markers are provided.
    Type: Grant
    Filed: April 23, 2010
    Date of Patent: June 13, 2017
    Assignee: INGENERON INCORPORATED
    Inventor: Eckhard U. Alt
  • Patent number: 9593309
    Abstract: A culture media, media supplement, or soluble matrix for cryopreservation or enhanced regenerative cell growth in culture and maintenance of multi-lineage differentiation potentiation. The inventive culture media, media supplement, or soluble matrix comprises a GAG composition comprising a sulfated GAG, such as chondroitin sulfate. A soluble matrix, a cell administration package or kit comprising the soluble matrix and a device for cell administration, and a method of use thereof, for administration of regenerative cells for treating a joint disease or other weakened or damaged tissue comprising the specified GAG compositions are further provided.
    Type: Grant
    Filed: May 8, 2015
    Date of Patent: March 14, 2017
    Assignees: ArthroDynamic Holdings, LLC, InGeneron Incorporated
    Inventors: Michael Coleman, Ivone Bruno, Rudy Martinez, Amir Sanchez, Eckhard Alt, Frank D. Marcum, Paul Shealy
  • Patent number: 9453200
    Abstract: A unitary apparatus for isolating cells from adipose tissue including a lipid separation processor with a dispersing head equipped with a plurality of ports and a digestion chamber for dissociation of the constituent cells disposed in adipose tissue. The lipid separating apparatus is useful for the separation of lipids and adipocytes from a mixed cell population. A cell seeding chamber may be attached to the cell isolation apparatus. The components of the apparatus may be packaged in modular kit form.
    Type: Grant
    Filed: August 28, 2014
    Date of Patent: September 27, 2016
    Assignee: INGENERON INCORPORATED
    Inventors: Ron Stubbers, Michael E. Coleman
  • Patent number: 9310300
    Abstract: A structure is configured to retain optical diagnostic assay components in a manner that enables them to be synergistically combined or coupled both mechanically and electrically with a conventional mobile electronic device (such as a smartphone), such that the pairing maintains a mutually advantageous relationship to provide a compact portable optical assay apparatus in which the optical assay portion has access to the image sensor, battery power, microprocessor, and data capture, analysis, storage, display and transmission capabilities of the smartphone, and the smartphone portion provides the overall apparatus with features of transportability, user interface, and information storage, analysis and retrieval, and transmission of assay results to a separate site, such as a site of records related to the provider of the sample being assayed. Methods of providing such structure and of performing an optical assay of sample material utilizing such structure are described.
    Type: Grant
    Filed: April 3, 2013
    Date of Patent: April 12, 2016
    Assignee: INGENERON INCORPORATED
    Inventors: Eckhard Alt, Jody Vykoukal, Michael Coleman
  • Publication number: 20150314041
    Abstract: This document describes methods and an apparatus for recovery of a cell-enriched matrix and cells (e.g., regenerative cells) from a tissue sample. In some embodiments, at least two rounds of acceleration and deceleration are performed.
    Type: Application
    Filed: February 10, 2015
    Publication date: November 5, 2015
    Applicant: InGeneron Incorporated
    Inventors: Eckhard U. Alt, Ron Stubbers, Michael E. Coleman
  • Publication number: 20150307845
    Abstract: This document describes methods and an apparatus for recovery of a cell-enriched matrix and cells (e.g., regenerative cells) from a tissue sample. In some embodiments, at least two rounds of acceleration and deceleration are performed.
    Type: Application
    Filed: February 10, 2015
    Publication date: October 29, 2015
    Applicant: InGeneron Incorporated
    Inventors: Eckhard U. Alt, Ron Stubbers, Michael E. Coleman
  • Publication number: 20150299643
    Abstract: This document describes methods and an apparatus for recovery of a cell-enriched matrix and cells (e.g., regenerative cells) from a tissue sample. In some embodiments, at least two rounds of acceleration and deceleration are performed.
    Type: Application
    Filed: February 10, 2015
    Publication date: October 22, 2015
    Applicant: InGeneron Incorporated
    Inventors: Eckhard U. Alt, Ron Stubbers, Michael E. Coleman
  • Patent number: 8951513
    Abstract: This document describes methods and an apparatus for recovery of a cell-enriched matrix and cells (e.g., regenerative cells) from a tissue sample. In some embodiments, at least two rounds of acceleration and deceleration are performed.
    Type: Grant
    Filed: December 16, 2011
    Date of Patent: February 10, 2015
    Assignee: Ingeneron Incorporated
    Inventors: Eckhard U. Alt, Michael E. Coleman, Ron Stubbers
  • Patent number: 8822202
    Abstract: A unitary apparatus for isolating cells from adipose tissue including a lipid separation processor with a dispersing head equipped with a plurality of ports and a digestion chamber for dissociation of the constituent cells disposed in adipose tissue. The lipid separating apparatus is useful for the separation of lipids and adipocytes from a mixed cell population. A cell seeding chamber may be attached to the cell isolation apparatus. The components of the apparatus may be packaged in modular kit form.
    Type: Grant
    Filed: October 26, 2012
    Date of Patent: September 2, 2014
    Assignee: Ingeneron Incorporated
    Inventors: Ron Stubbers, Michael Coleman