Patents Assigned to Ingeneron Incorporated
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Patent number: 9675673Abstract: Methods, apparatus and compositions are provided for treatment of cancer of a selected organ by intraluminal delivery of oncolytic agents through a blood vessel or duct leading to the cancer tissue. During the time the oncolytic agents are being applied to the targeted tissue downstream, the designated vessel or duct can be selectively occluded to increase concentration and pressure of the applied agents at the target site. Oncolytic compositions including oncolytic viruses formulated with delivery visualization markers are provided.Type: GrantFiled: April 23, 2010Date of Patent: June 13, 2017Assignee: INGENERON INCORPORATEDInventor: Eckhard U. Alt
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Patent number: 9593309Abstract: A culture media, media supplement, or soluble matrix for cryopreservation or enhanced regenerative cell growth in culture and maintenance of multi-lineage differentiation potentiation. The inventive culture media, media supplement, or soluble matrix comprises a GAG composition comprising a sulfated GAG, such as chondroitin sulfate. A soluble matrix, a cell administration package or kit comprising the soluble matrix and a device for cell administration, and a method of use thereof, for administration of regenerative cells for treating a joint disease or other weakened or damaged tissue comprising the specified GAG compositions are further provided.Type: GrantFiled: May 8, 2015Date of Patent: March 14, 2017Assignees: ArthroDynamic Holdings, LLC, InGeneron IncorporatedInventors: Michael Coleman, Ivone Bruno, Rudy Martinez, Amir Sanchez, Eckhard Alt, Frank D. Marcum, Paul Shealy
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Patent number: 9453200Abstract: A unitary apparatus for isolating cells from adipose tissue including a lipid separation processor with a dispersing head equipped with a plurality of ports and a digestion chamber for dissociation of the constituent cells disposed in adipose tissue. The lipid separating apparatus is useful for the separation of lipids and adipocytes from a mixed cell population. A cell seeding chamber may be attached to the cell isolation apparatus. The components of the apparatus may be packaged in modular kit form.Type: GrantFiled: August 28, 2014Date of Patent: September 27, 2016Assignee: INGENERON INCORPORATEDInventors: Ron Stubbers, Michael E. Coleman
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Patent number: 9310300Abstract: A structure is configured to retain optical diagnostic assay components in a manner that enables them to be synergistically combined or coupled both mechanically and electrically with a conventional mobile electronic device (such as a smartphone), such that the pairing maintains a mutually advantageous relationship to provide a compact portable optical assay apparatus in which the optical assay portion has access to the image sensor, battery power, microprocessor, and data capture, analysis, storage, display and transmission capabilities of the smartphone, and the smartphone portion provides the overall apparatus with features of transportability, user interface, and information storage, analysis and retrieval, and transmission of assay results to a separate site, such as a site of records related to the provider of the sample being assayed. Methods of providing such structure and of performing an optical assay of sample material utilizing such structure are described.Type: GrantFiled: April 3, 2013Date of Patent: April 12, 2016Assignee: INGENERON INCORPORATEDInventors: Eckhard Alt, Jody Vykoukal, Michael Coleman
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Publication number: 20150314041Abstract: This document describes methods and an apparatus for recovery of a cell-enriched matrix and cells (e.g., regenerative cells) from a tissue sample. In some embodiments, at least two rounds of acceleration and deceleration are performed.Type: ApplicationFiled: February 10, 2015Publication date: November 5, 2015Applicant: InGeneron IncorporatedInventors: Eckhard U. Alt, Ron Stubbers, Michael E. Coleman
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Publication number: 20150307845Abstract: This document describes methods and an apparatus for recovery of a cell-enriched matrix and cells (e.g., regenerative cells) from a tissue sample. In some embodiments, at least two rounds of acceleration and deceleration are performed.Type: ApplicationFiled: February 10, 2015Publication date: October 29, 2015Applicant: InGeneron IncorporatedInventors: Eckhard U. Alt, Ron Stubbers, Michael E. Coleman
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Publication number: 20150299643Abstract: This document describes methods and an apparatus for recovery of a cell-enriched matrix and cells (e.g., regenerative cells) from a tissue sample. In some embodiments, at least two rounds of acceleration and deceleration are performed.Type: ApplicationFiled: February 10, 2015Publication date: October 22, 2015Applicant: InGeneron IncorporatedInventors: Eckhard U. Alt, Ron Stubbers, Michael E. Coleman
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Methods and apparatus for enhanced recovery of cells and of cell-enriched matrix from tissue samples
Patent number: 8951513Abstract: This document describes methods and an apparatus for recovery of a cell-enriched matrix and cells (e.g., regenerative cells) from a tissue sample. In some embodiments, at least two rounds of acceleration and deceleration are performed.Type: GrantFiled: December 16, 2011Date of Patent: February 10, 2015Assignee: Ingeneron IncorporatedInventors: Eckhard U. Alt, Michael E. Coleman, Ron Stubbers -
Patent number: 8822202Abstract: A unitary apparatus for isolating cells from adipose tissue including a lipid separation processor with a dispersing head equipped with a plurality of ports and a digestion chamber for dissociation of the constituent cells disposed in adipose tissue. The lipid separating apparatus is useful for the separation of lipids and adipocytes from a mixed cell population. A cell seeding chamber may be attached to the cell isolation apparatus. The components of the apparatus may be packaged in modular kit form.Type: GrantFiled: October 26, 2012Date of Patent: September 2, 2014Assignee: Ingeneron IncorporatedInventors: Ron Stubbers, Michael Coleman