Abstract: Described here is a method for reducing or preventing Pseudomonas aeruginosa biofilm formation in a human subject in need thereof, comprising administering to the human subject a first composition comprising (a) an antigen-binding polypeptide that binds Pf-family bacteriophage, or (b) a vaccine against Pf-family bacteriophage. Also described is an antigen-binding polypeptide that binds specifically to a CoaB protein of Pf-family bacteriophage or fragment thereof.
Type:
Grant
Filed:
January 29, 2024
Date of Patent:
June 23, 2026
Assignee:
Inimmune Corp.
Inventors:
Paul L. Bollyky, William Parks, Patrick Secor